How do mRNA vaccines work?

mRNA vaccines work by introducing a piece of mRNA that corresponds to a viral protein, usually a small piece of a protein found on the virus's outer membrane. (Individuals who get an mRNA vaccine are not exposed to the virus, nor can they become infected by the vaccine.)

How long has the mRNA vaccine been around?

mRNA vaccines have been studied before for flu, Zika, rabies, and cytomegalovirus (CMV). As soon as the necessary information about the virus that causes COVID-19 was available, scientists began designing the mRNA instructions for cells to build the unique spike protein into an mRNA vaccine.

Is there a live virus in the mRNA COVID-19 vaccines?

The mRNA vaccines do not contain any live virus. Instead, they work by teaching our cells to make a harmless piece of a “spike protein,” which is found on the surface of the virus that causes COVID-19. After making the protein piece, cells display it on their surface.

How does the COVID-19 vaccine work?

COVID-19 vaccines help our bodies develop immunity to the virus that causes COVID-19 without us having to get the illness.

Will a COVID-19 vaccine alter my DNA?

No. COVID-19 mRNA vaccines do not change or interact with your DNA in any way.

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Are long term side effects possible with the COVID-19 vaccine?

Benefits of Vaccination Outweigh the Risks Serious side effects that could cause a long-term health problem are extremely unusual following any vaccination, including COVID-19 vaccination.

What are some common side effects of the COVID-19 vaccine?

According to the CDC, common responses to the vaccine include arm soreness, tiredness, headache, muscle pain, chills and/or fever.

How does the COVID-19 vaccine help stop the spread of new strains?

As we vaccinate as many people as possible, as quickly as possible, we can stop the spread of the coronavirus. A reduction in transmission of the virus means fewer opportunities for it to mutate, which can help prevent the emergence of any other strains.

How long do COVID-19 vaccines last?

It is normal for virus-fighting antibodies—such as those that are stimulated by a COVID-19 vaccine—to wane over time. Monitoring antibody levels in the blood is one way to measure vaccine efficacy and research has found that protection remains high for six months after the second shot of a Pfizer or Moderna vaccine.

What does the COVID-19 vaccine prevent?

Scientists are monitoring how long COVID-19 vaccine protection lasts. COVID-19 vaccines work well to prevent severe illness, hospitalization, and death. However, public health experts are seeing decreases in the protection COVID-19 vaccines provide over time, especially for certain groups of people.

Does the COVID-19 vaccine have a live virus?

None of the vaccines authorized for use in the U.S. contain a live virus. mRNA and viral vector vaccines are the two types of currently authorized COVID-19 vaccines available.

What are the severe allergic reactions to COVID-19 mRNA vaccines?

“Overall, severe allergic reactions to COVID-19 mRNA vaccines, including life-threatening anaphylaxis reactions such as low blood pressure and difficulty breathing, are rare, on the order of five cases per million vaccine doses administered,” noted Dr. Guerrerio.

Can you get the COVID-19 vaccine if you have an allergic reaction?

If you have had an immediate allergic reaction (a reaction that started within 4 hours) to any vaccine other than a COVID-19 vaccine or any injectable therapy, you may still be able to get a COVID-19 vaccine. However, your doctor may refer you to an allergy and immunology specialist for additional care or advice.

Do mRNA COVID-19 vaccines cause heart inflammation?

These cases typically occur in male adolescents and young adults after the second dose, and within a week of vaccination. It is important to seek medical care if symptomatic (chest pain, shortness of breath, having a fast beating, fluttering, or pounding heart).

Are there any safety concerns concerning mRNA technology of the Pfizer-BioNTech COVID-19 Vaccine?

FDA does not have specific safety concerns with a vaccine that utilizes this technology.

How long does COVID-19 rebound last?

So far there have been no reports of severe illness in those who have experienced covid rebound, and most people seem to recover and stop testing positive around three days later without needing additional covid-19 treatment.

How long does the protection from Pfizer and Moderna's COVID-19 booster vaccine last?

The most recent research from the CDC suggests that protection from the Pfizer and Moderna COVID-19 vaccines starts to fade around 4 months after a booster dose.

How long does it take for immunity to wane after receiving the COVID-19 vaccine?

A study published by the U.S. Centers for Disease Control and Prevention found that immunity against severe COVID-19 begins to wane four months after receiving a so-called "booster" third dose of the Pfizer or Moderna vaccines.

What's the efficacy of the Pfizer COVID-19 vaccine after 90 days?

Among adults who received 2 doses of the Pfizer-BioNTech (BNT162b2) mRNA COVID-19 vaccine, the risk for SARS-CoV-2 infection increased gradually after 90 days, according to results of a study published in BMJ.

Are the existing COVID-19 vaccines effective against new variants?

With each new variant, the COVID vaccines and their boosters remain our most powerful tool to fight all the strains of COVID-19 because the vaccines continue to significantly reduce the severity of the illness.

Could the COVID-19 vaccine protect me from spreading COVID-19?

Staying up to date with COVID-19 vaccination also means you are less likely to spread the disease to others and increases your protection against new variants of SARS-CoV-2, the virus that causes COVID-19.

Does the COVID-19 vaccine reduce the transmission of the Delta variant?

This study confirms that COVID-19 vaccination reduces the risk of delta variant infection and also accelerates viral clearance in the context of the delta variant. However, this study unfortunately also highlights that the vaccine effect on reducing transmission is minimal in the context of delta variant circulation.

What are the possible side effects of the Moderna and Pfizer COVID-19 vaccines?

Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. If these side effects occur, they should go away in a few days. A few side effects are serious, but rare.

What are the common side effects of the Pfizer-BioNTech COVID-19 vaccine?

Commonly reported side effects in the clinical trial included injection site pain (sore arm), redness and swelling, fatigue, headache, muscle and/or joint pain, chills, fever, swollen lymph nodes, nausea and decreased appetite.

Is it normal that I feel worse after second COVID-19 shot?

This is normal and expected, but it doesn't happen to everyone. Even if you feel worse after the second shot, the side effects should still resolve within a few days.