How can I prevent my baby from having a cleft lip?

What can you do to help prevent cleft lip and cleft palate in your baby?
  1. Take folic acid. ...
  2. Don't smoke or drink alcohol. ...
  3. Get a preconception checkup. ...
  4. Get to a healthy weight before pregnancy and talk to your provider about gaining a healthy amount of weight during pregnancy.
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What foods can cause a cleft lip?

The Western dietary pattern, eg, high in meat, pizza, legumes, and potatoes, and low in fruits, was associated with a higher risk of a cleft lip or cleft palate (odds ratio 1.9; 95% confidence interval 1.2-3.1).
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What causes a baby to have a cleft lip?

A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This results in an opening in the upper lip. The opening in the lip can be a small slit or it can be a large opening that goes through the lip into the nose.
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Who is most at risk for cleft lip?

Cleft lip, with or without cleft palate, affects one in 700 babies annually, and is the fourth most common birth defect in the U.S. Clefts occur more often in children of Asian, Latino, or Native American descent. Compared with girls, twice as many boys have a cleft lip, both with and without a cleft palate.
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Can Prenatals prevent cleft lip?

A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby's chances of being born with a facial cleft.
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Preventing Cleft Lip



Can lack of folic acid cause cleft palate?

Lack of folic acid early in pregnancy is known to cause neural tube defects such as spina bifida, but this is the first study ever to show a strong association between maternal folic acid intake and the risk of a baby developing cleft lip and cleft palate.
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What week of pregnancy does cleft lip happen?

Overall, about 1 in 800 births are affected by cleft lip and/or cleft palate. The face and upper lip develop during the 5th to 9th weeks of pregnancy. Most cleft problems can either be picked up at the routine 20-week scan or soon after birth.
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Can a cleft lip be seen on ultrasound?

Cleft lip may be detected with ultrasound beginning around the 13th week of pregnancy. As the fetus continues developing, it may be easier to accurately diagnose a cleft lip. Cleft palate that occurs alone is more difficult to see using ultrasound.
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What increases risk of cleft lip?

Parents with a family history of cleft lip or cleft palate face a higher risk of having a baby with a cleft. Exposure to certain substances during pregnancy. Cleft lip and cleft palate may be more likely to occur in pregnant women who smoke cigarettes, drink alcohol or take certain medications. Having diabetes.
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Is a cleft lip genetic?

The causes of cleft lip and cleft palate (or both) are unknown, although hereditary (genetic) factors sometimes play a small role. A cleft lip or cleft palate (or both) is not caused by anything the parents did or did not do during the pregnancy.
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What deficiencies cause cleft palate?

Deficiency of B vitamins and folic acid in maternal diet is another commonly associated cause of cleft lip and palate in the new born.
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Can cleft palate be passed down?

There may be a grandparent, parent, cousin, brother or sister, or another relative who has had a cleft palate. This may be passed on from generation to generation. However, only 1 out of every 5 clefts are inherited. There are many children born with cleft palates who have no family history of clefting.
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Can cleft lip Be Fixed?

The cleft lip usually is corrected early in a child's life, between 3 to 6 months of age, but sometimes later. Cleft lip surgery will correct the cleft and usually will leave minimal scarring. Virtually every child born with a cleft lip is able to lead a healthy, happy life once the cleft has been repaired.
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Can caffeine cause cleft lip?

Data from animal studies suggest that large single doses of caffeine may cause palatal clefts as well as other birth defects (9), although studies of coffee consumption in humans have provided little evidence of teratogenic effects (10).
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Which country has the highest rate of cleft palate?

Data was captured from 55 countries. According to most recent data, the highest total rates of CLP were reported in Venezuela (38 cases/10,000 births), Iran (36 cases/10,000 births) and Japan (30 cases/10,000 births).
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What foods have folic acid?

Food Sources
  • Dark green leafy vegetables (turnip greens, spinach, romaine lettuce, asparagus, Brussels sprouts, broccoli)
  • Beans.
  • Peanuts.
  • Sunflower seeds.
  • Fresh fruits, fruit juices.
  • Whole grains.
  • Liver.
  • Seafood.
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What gene causes cleft lip?

Mutations in the HYAL2 gene responsible for CLP

Hyaluronan is a carbohydrate polymer usually found in connective tissue and the hard palate. Researchers performed enzyme assays, which revealed that the mutations reduced the levels of the HYAL2 protein.
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What medication increases the risk for having a fetus with a cleft lip?

According to the American Dental Association (ADA), pregnant women who take the drug Topiramate increase the risks of oral cleft in babies. This conclusion stems from data the North American Antiepileptic Drug Pregnancy Registry collected, which the Food and Drug Administration (FDA) released in a safety alert.
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Why is cleft lip more common in males?

Compared to females, clefts in males more commonly occur in both the early and late embryonic periods are therefore more often combined clefts of the primary and secondary palate, and are more frequently the result of differentiation defects and combined fusion and differentiation defects.
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How can you tell if a baby has a cleft lip?

Newborns have an oral exam soon after they're born. Doctors usually find a cleft palate when they examine the inside of a baby's mouth during this exam.
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What can you see at 36 week ultrasound?

The scan reveals the position of your baby in the womb which usually stabilises from around 36 weeks into your pregnancy. Your sonographer will be able to see whether your baby is in the normal position (head down), breech position (feet first) or lying sideways (transverse position).
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Is cleft lip diagnosed before birth?

Cleft palate and cleft lip can be detected in-utero (before birth). If an ultrasound reveals your baby has these conditions, a treatment plan can be developed even before the child is born. Pregnant women should not smoke or expose themselves to second-hand smoke.
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Do they check for cleft lip at 20 week ultrasound?

The initial diagnosis of a cleft lip or palate usually happens when the expectant mother has a scan at approximately 20 weeks of pregnancy. The ultrasound scan is generally conducted by a trained sonographer who can identify the appearance of a cleft lip.
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Can a 12 week ultrasound detect cleft palate?

We suggest that screening for anomalies is possible in the late first trimester. This case demonstrates and emphasizes that early and accurate diagnosis of cleft lip and palate in the first trimester, as early as 12 weeks' gestation, is a real possibility.
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How does folic acid affect a fetus?

When the baby is developing early during pregnancy, folic acid helps form the neural tube. Folic acid is very important because it can help prevent some major birth defects of the baby's brain (anencephaly) and spine (spina bifida).
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