Does vitamin D deficiency cause Paget's disease?

Prevalence of vitamin D deficiency is higher in patients with Paget's disease of bone compared with age-matched controls. Arq Bras Endocrinol Metabol.

Does vitamin D Help with Paget's disease?

Abstract. Adequate vitamin D status is essential for skeletal health. Paget's disease of bone (PDB) is a common metabolic skeletal disorder, but data regarding the vitamin D status in PDB patients are lacking.

What are the causes of Pagets disease?

The cause of Paget's disease of bone is unknown. Scientists suspect a combination of environmental and genetic factors contribute to the disease. Several genes appear to be linked to getting the disease.

What disorders are caused by vitamin D deficiency?

In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend. African American infants and children are at higher risk of getting rickets. In adults, severe vitamin D deficiency leads to osteomalacia. Osteomalacia causes weak bones, bone pain, and muscle weakness.

Is Paget's disease related to osteoporosis?

Related Disorders

Although Paget's disease and osteoporosis can occur in the same person, they are completely different disorders with different causes. Despite their marked differences, many treatments for Paget's disease are also used to treat osteoporosis.

Warning signs, risks of Vitamin D deficiency

Is Paget's disease of the bone an autoimmune disease?

Paget's disease of bone is a chronic autoimmune inflammatory disease that leads to an increase in bone reabsorption. While depression is extensively described in Paget's disease, affecting up to 50% of patients, the prevalence of manic episodes is unknown.

What foods are good for Paget's disease?

What are the symptoms of severe vitamin D deficiency?

The most common cause is lack of exposure to sunlight, usually when the diet is deficient in vitamin D, but certain disorders can also cause the deficiency. Without enough vitamin D, muscle and bone weakness and pain occur.

What are the long term effects of low vitamin D?

Patients with a prolonged and severe vitamin D deficiency can experience symptoms associated with secondary hyperparathyroidism including bone pain, arthralgias, myalgias, fatigue, muscle twitching (fasciculations), and weakness. Fragility fractures may result from chronic vitamin D deficiency leading to osteoporosis.

What happens when your vitamin D is low?

Vitamin D deficiency occurs when the body doesn't get enough vitamin D from sunlight or diet. Vitamin D deficiency can cause loss of bone density, osteoporosis, and broken bones. Vitamin D is sometimes called the sunshine vitamin because your body makes it from cholesterol when your skin is exposed to sunlight ( 1 ).

Can Paget's disease symptoms come and go?

In most cases, Paget's disease affects one breast, and the symptoms may come and go. This means symptoms may cycle through, appearing to improve and then worsen again. The symptoms may look similar to eczema or other such skin conditions.

Can you prevent Paget's disease?

While there are no known ways to prevent Paget's disease from occurring, eating a healthy diet with sufficient calcium and vitamin D, and getting regular exercise, are important components in maintaining skeletal health and joint mobility.

How do you tell if you have Paget's disease?

How do you get rid of Paget's disease?

Paget disease can be treated by removing the entire breast (mastectomy) or breast-conserving surgery (BCS) followed by whole-breast radiation therapy. If BCS is done, the entire nipple and areola area also needs to be removed. If invasive cancer is found, the lymph nodes under the arm will be checked for cancer.

Where does Paget's disease start?

Symptoms of Paget's disease of the nipple

Paget's disease of the nipple always starts in the nipple and may extend to the areola. It appears as a red, scaly rash on the skin of the nipple and areola. The affected skin is often sore and inflamed, and it can be itchy or cause a burning sensation.

Is there a blood test for Paget's disease?

Paget's disease of bone can be diagnosed with a blood test and an X-ray or scan.

Can low vitamin D cause itching?

Skin rashes

You may experience red, dry and itchy skin due to vitamin D deficiency. Intake of vitamin D can help you treat such skin problems. It can also reduce skin rashes.

How long does it take to recover from vitamin D deficiency?

“If you put people on 2,000-4,000 [milligrams] of vitamin D based on what their deficient value was, you can usually get them corrected in four to six weeks, which is when you are really going to need the vitamin D.

Who is most at risk for vitamin D deficiency?

Can low vitamin D cause neurological symptoms?

Vitamin D is an important vitamin that plays a role in many different functions in the body. Vitamin D deficiency can cause a number of neurological problems, including fatigue, memory loss, and difficulty concentrating.

What stops the absorption of vitamin D?

Therefore, conditions that affect the gut and digestion, like celiac disease, chronic pancreatitis, Crohn's disease, and cystic fibrosis, can reduce vitamin D absorption.

Does exercise help Paget's disease?

Physical therapy (PT) can play an important role in the treatment process and rehabilitation of patients with Paget disease by helping to maintain or improve muscle strength, maintain joint range of motion (ROM) and flexibility, increase endurance, and avoid deconditioning.

What is the life expectancy of someone with Paget's disease?

In that study, the British General Practice Research Database identified 2465 patients diagnosed with Paget's disease of bone from 1988 to 1999; retrospective review indicated that 5-yr survival was 67% in patients with Paget's disease compared with 72% in control patients.

What are the long term effects of Paget's disease?

If Paget's disease of bone affects the skull, there's a significant risk that it could lead to permanent hearing loss and possibly total deafness. This can occur as a result of damage to the bones or nerves that connect the ears to the brain.

Is Paget's disease a form of arthritis?

Sometimes, this bone pain, which is the most common symptom of the disease, is mistaken for arthritis or other disorders. Generally, symptoms develop slowly, and the disease does not spread to normal bones. Paget's disease can affect any bone, but usually occurs in: Spine.