Does stress cause granuloma annulare?

Some reports associate chronic stress with granuloma annulare as a trigger of the disease. Granuloma annulare also has some predilection for the sun-exposed areas and photodamaged skin.
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What causes granuloma annulare to flare up?

The exact cause of granuloma annulare is unknown (idiopathic). Numerous theories exist linking the cause to trauma, sun exposure, thyroid disease, tuberculosis, and various viral infections. However, no definitive proof has been shown for any of these theories.
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How do you calm granuloma annulare?

Treatment options include:
  1. Corticosteroid creams or ointments. Prescription-strength products may help improve the appearance of the bumps and help them disappear faster. ...
  2. Corticosteroid injections. ...
  3. Freezing. ...
  4. Light therapy. ...
  5. Oral medications.
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What kind of trauma causes granuloma annulare?

Doctors also think granuloma annulare is related to triggers, such as: Skin injuries such as insect bites or trauma. Certain medications, like allopurinol (Aloprim®, Zyloprim®) Some diseases, like human immunodeficiency virus (HIV) and hepatitis C.
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Is granuloma annulare an auto immune disease?

This association certainly supports the theory that granuloma annulare is within the spectrum of autoimmune diseases. It turns out that both disorders share the histocompatibility HLA-Bw35 antigen in some patients.
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What medications trigger granuloma annulare?

Various drugs which have been implicated in etiology of granuloma annulare include amlodipine, gold, allopurinol, diclofenac, quinidine and intranasal calcitonin.
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Can diet help granuloma annulare?

A diagnosis of generalized erythematous granuloma annulare was established based on the clinical and histopathological findings, especially with the distribution on more than one anatomic site. A lipid-lowering diet for three months resulted in major improvement of hyperlipidemia and remission of the skin lesions.
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Can thyroid problems cause granuloma annulare?

The cause of granuloma annulare is unknown and it is found in patients of all ages. The condition tends to be seen in otherwise healthy people. Sometimes it is associated with diabetes or thyroid disease.
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Is the sun good for granuloma annulare?

Light therapy: Exposing the skin with granuloma annulare to ultraviolet (UV) light in a controlled way can be helpful. Some people receive a type of light therapy called PUVA.
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Does Vitamin E help granuloma annulare?

In our opinion, topically applied vitamin E for granuloma annulare allows fast and uncomplicated administration of drug to the lesion, it has a good therapeutic ratio without any adverse effects and can be used in children without precautions and thus, lastly, is cost-efficient.
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Why do granulomas form?

Granulomas form when immune cells clump together and create tiny nodules at the site of the infection or inflammation. A granuloma is the body's way: to contain an area of bacterial, viral or fungal infection so it can try to keep it from spreading; or. to isolate irritants or foreign objects.
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Can granuloma annulare be cancerous?

Generalized granuloma annulare can be associated with breast cancer. Atypical granuloma annulare especially in older patients should alert physicians to the possibility of an occult malignancy.
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Is granuloma annulare related to diabetes?

Granuloma annulare (GA) is usually a self-limited, benign granulomatous disease of the dermis and subcutaneous tissue. It's generalized or disseminated form is associated with underlying diabetes mellitus and at times it precedes the sign and symptoms of diabetes mellitus.
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What are the side effects of granuloma?

Granulomas themselves don't usually have noticeable symptoms. But the conditions that cause them, such as sarcoidosis, tuberculosis, histoplasmosis, and others, may create symptoms.
...
Some of these include:
  • Shortness of breath.
  • Wheezing.
  • Chest pain.
  • Fever.
  • Dry cough that won't go away.
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Does prednisone help granuloma annulare?

Clinical examination and biopsy were consistent with GA. Topical steroids were initially effective, but with each recurrence, the disease became more resistant to therapy. Oral prednisone (60mg) was effective, but the disease recurred quickly after the drug was discontinued.
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Is granuloma annulare a ringworm?

Granuloma annulare is often mistaken for ringworm. Ringworm, however, is usually scaly and itchy. Granuloma annulare is not. This rash can also be mistaken for bug bites or a rash caused by a tick with Lyme disease.
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Can granuloma annulare be misdiagnosed?

Granuloma annulare can be mistaken for other common annular skin conditions such as tinea corporis, pityriasis rosea, nummular eczema, psoriasis, or erythema migrans of Lyme disease. The lack of any surface changes to the skin is the key feature that distinguishes granuloma annulare from these other skin conditions.
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What is granuloma?

A granuloma is a small area of inflammation. Granulomas are often found incidentally on an X-ray or other imaging test done for a different reason. Typically, granulomas are noncancerous (benign). Granulomas frequently occur in the lungs, but can occur in other parts of the body and head as well.
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What doctor treats granuloma annulare?

A dermatologist usually diagnoses granuloma annulare by examining the patient's skin.
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What percentage of people have granuloma annulare?

The prevalence of granuloma annulare is estimated to be 0.1% to 0.4%, and the estimated incidence is 0.1% to 0.4%. Women are affected more commonly than men, and the disease can affect persons of any age. More than two-thirds of patients are 30 years of age or younger.
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Is type 2 diabetes an autoimmune disease?

Type 2 Diabetes: Is It an Autoimmune Disease? For decades, doctors and researchers believed that type 2 diabetes was a metabolic disorder. This type of disorder occurs when your body's natural chemical processes don't work properly. Recent research suggests that type 2 diabetes may actually be an autoimmune disease.
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What are the causes of sugar diabetes?

It's clear that certain factors increase the risk, however, including:
  • Weight. The more fatty tissue you have, the more resistant your cells become to insulin.
  • Inactivity. ...
  • Family history. ...
  • Race or ethnicity. ...
  • Age. ...
  • Gestational diabetes. ...
  • Polycystic ovary syndrome. ...
  • High blood pressure.
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What cancers are associated with granuloma annulare?

Which malignancies have been associated with granuloma annulare?
  • Non-Hodgkin lymphoma.
  • Hodgkin lymphoma.
  • Acute myelogenous leukemia.
  • Chronic lymphocytic leukemia.
  • Myelomonocytic leukemia.
  • Large granular lymphocytic leukemia.
  • Myelodysplastic syndrome.
  • T-cell lymphoma.
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Does lymphoma cause granuloma annulare?

Conclusion: Granuloma annulare with atypical clinical presentations may be associated with an underlying hematopoietic malignancy and may be part of a generalized granulomatous reaction to malignant lymphoma.
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Can granuloma annulare be itchy?

Granuloma annulare is a rash that often looks like a ring of small pink, purple or skin-coloured bumps. It usually appears on the back of the hands, feet, elbows or ankles. The rash is not usually painful, but it can be slightly itchy. It's not contagious and usually gets better on its own within a few months.
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