Does pernicious anemia shorten your life?

With proper treatment, people who have pernicious anemia can recover, feel well, and live normal lives. If you have complications of pernicious anemia, such as nerve damage, early treatment may help reverse the damage.
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Can pernicious anemia cause death?

Failure to diagnose and treat in time, however, may result in permanent neurological damage, excessive fatigue, depression, memory loss, and other complications. In severe cases, the neurological complications of pernicious anemia can lead to death – hence the name, "pernicious", meaning deadly.
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How serious is pernicious anemia?

Pernicious anemia, one of the causes of vitamin B12 deficiency, is an autoimmune condition that prevents your body from absorbing vitamin B12. Left untreated, pernicious anemia can cause serious medical issues, including irreversible damage to your nervous system.
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Why is pernicious anemia fatal?

If your body doesn't absorb enough from the food you eat, your red blood cells will be too big to travel well through your body. Because of this, your body will make less of them. And the cells that are made will die off sooner than they should.
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Is B12 deficiency life threatening?

B12 deficiency. Delay in diagnosis and treatment resulted in a near fatal presentation of a common disease. The primary care physician should be aware that there is a window of opportunity for diagnosis and treatment; several complications of Vit. B12 deficiency are irreversible if early treatment is not provided.
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Does pernicious anemia shorten your life?



Is pernicious anemia a disability?

If you suffer from pernicious anemia or subacute combined degeneration of the spinal cord, and it affects your ability to function at work, you may be eligible for Social Security disability benefits.
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Do I need B12 injections for life?

If your vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, you'll usually need to have an injection of hydroxocobalamin every 2 to 3 months for the rest of your life.
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Can pernicious anemia turn into leukemia?

Individuals with pernicious anemia were also at significantly increased risk of developing myeloma (OR: 1.55), acute myeloid leukemia (OR: 1.68) and myelodysplastic syndromes (OR: 2.87).
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Does pernicious anemia affect the heart?

Autoimmune pernicious anaemia as a cause of collapse, heart failure and marked panyctopaenia in a young patient.
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What triggers pernicious anemia?

Common causes of pernicious anemia include: Weakened stomach lining (atrophic gastritis) An autoimmune condition in which the body's immune system attacks the actual intrinsic factor protein or the cells in the lining of your stomach that make it.
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Can you drink alcohol if you have pernicious anemia?

Eat a varied diet. Include foods with a lot of vitamin B12, such as eggs, milk, and meat. Do not drink alcohol while you are being treated. Alcohol can prevent the body from absorbing vitamin B12.
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Does pernicious anemia run in families?

Pernicious anemia is mainly thought to be an autoimmune disorder that hurts the parietal cells in the stomach and inhibits the proper functioning of intrinsic factor. However, pernicious anemia may also have a genetic component to it as well. It may potentially run in families.
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How often should you have B12 injections for pernicious anemia?

For Pernicious Anemia

B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month. Thereafter, 100 mcg should be injected once a month for life.
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Is pernicious anemia a chronic condition?

Pernicious anemia is a chronic disease that progresses slowly and steadily. In the past, before much was known about the disease and there was no treatment, it would eventually cause death after many years of suffering.
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What age does pernicious anemia occur?

In adults, symptoms of pernicious anemia are usually not seen until after age 30. The average age of diagnosis is age 60. You are more likely to develop this disease if you: Are Scandinavian or Northern European.
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What happens if B12 is left untreated?

If your anemia goes untreated for a long time, it can lead to heart failure. That's because your heart has to work harder. B12-related anemia may also raise the chances you'll have a heart attack, stroke, or other cardiovascular problem.
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Does pernicious anemia cause back pain?

Generally, once pernicious anemia is diagnosed, intramuscular B12 injections are continued indefinitely--typically monthly. As to what specific questions to ask your doctor, you might begin with what is causing your symptoms of lower back and leg pain.
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Does pernicious anemia cause joint pain?

The drop in Vitamin B12 was a major cause for her health-related issues, suggested doctors. Speaking to Sakal Times, Dr Neeraj Adkar, an orthopedist with the Saishree Hospital, said that vitamin B12 deficiency leads to pernicious anaemia, with knee pain.
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Can anemia lead to death?

Death. Some inherited anemias, such as sickle cell anemia, can lead to life-threatening complications. Losing a lot of blood quickly results in acute, severe anemia and can be fatal. Among older people, anemia is associated with an increased risk of death.
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Is pernicious anemia an auto immune disease?

Pernicious anemia is thought to be an autoimmune disease. Autoimmune disorders are caused when the body's natural defenses (e.g., antibodies) against “foreign” or invading organisms begin to attack healthy tissue for unknown reasons.
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What cancers cause low B12?

Which malignancies are associated with pernicious anemia?
  • Tonsillar cancer (OR, 2.00)
  • Hypopharyngeal cancer (OR, 1.92)
  • Esophageal squamous cell carcinoma (OR, 2.12)
  • Small intestinal cancer (OR, 1.63)
  • Liver cancer (OR, 1.49)
  • Myeloma (OR, 1.55)
  • Acute myeloid leukemia (OR, 1.68)
  • Myelodysplastic syndrome (OR, 2.87)
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Who is most at risk for pernicious anemia?

Pernicious anemia is more common in people of Northern European and African descent than in other ethnic groups. Older people also are at higher risk for the condition. This is mainly due to a lack of stomach acid and intrinsic factor, which prevents the small intestine from absorbing vitamin B12.
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Why am I not better after B12 injections?

Though this vitamin is naturally produced in your body, the injection of additional B12 may cause some internal side effects you should know about. It is common to experience headaches, dizziness, and weakness immediately after the injection. These should fade fairly quickly.
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Is the NHS stopping B12 injections?

Nationally, all NHS organisations will be stopping B12 injections. Some will offer oral on a script, other areas have stopped and asked patients to purchase it.
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How long does a B12 injection last?

Generally, the results of vitamin B12 injections can last about one week, but it is vital to have this administered by a healthcare provider. Also, the healthcare provider will determine the appropriate B12 dosage, depending on the current medical condition and diet.
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