Does lymphoma cause thigh pain?

Primary skeletal muscle lymphoma is exceptionally rare form of DLBCL
DLBCL
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphomas, constituting up to 40% of cases globally (1). Global epidemiological data on DLBCL are limited, but the estimated incidence is 7 per 100,000 in the USA (2).
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC5796369
, particularly in the thigh and calf areas. The main symptoms of the disease typically include presence of a mass, pain and swelling (5).
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Can you have lymphoma in your thigh?

About 1/3 of these lymphomas are confined to one part of the body when they are localized. In the case of a 78-year-old man, an extensive tumour was located on the right thigh.
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Can lymphoma cause pain in legs?

Possible symptoms include swelling, feelings of tightness, heaviness, aching or soreness. It usually affects an arm or a leg, although it can affect other areas of your body, depending on where the lymphoma is. Other conditions can also cause lymphoedema.
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Does lymphoma affect the legs?

Primary cutaneous diffuse large B-cell lymphoma, leg type: This is a fast-growing lymphoma that begins as large nodules, mainly on the lower legs. It occurs most often in older people, and is more common in women than men.
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Where do you feel lymphoma pain?

Lymphomas that start or grow in the abdomen (belly) can cause swelling or pain in the abdomen. This could be from lymph nodes or organs such as the spleen or liver enlarging, but it can also be caused by the build-up of large amounts of fluid.
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Signs and symptoms of lymphoma - Mayo Clinic



What are the warning signs of lymphoma?

Signs and symptoms of lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Shortness of breath.
  • Unexplained weight loss.
  • Itchy skin.
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What were your first signs of lymphoma?

Here are 11 early signs of lymphoma:
  • Swollen lymph nodes: ...
  • Fever and/or chills: ...
  • Night sweats: ...
  • Swelling of the abdomen: ...
  • Loss of appetite: ...
  • Persistent, overwhelming fatigue: ...
  • Easy bruising or bleeding: ...
  • Coughing, chest pressure, or shortness of breath:
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What is lymphoma leg?

Primary cutaneous diffuse large B-cell lymphoma, leg-type, is a very rare, fast-growing (high-grade) type of lymphoma. It typically develops in people over 70 and is twice as common in women as men. It usually develops as one or more large, bluish-red nodules that grow rapidly over a few weeks or months.
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Can swollen lymph nodes cause leg pain?

Lymphedema is swelling that's caused by a collection of too much lymph fluid. It usually happens in your arms and legs, but it can happen in other parts of your body, as well. This swelling may cause pain and limit how well the affected area moves.
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What is leg lymphedema?

Lymphedema refers to tissue swelling caused by an accumulation of protein-rich fluid that's usually drained through the body's lymphatic system. It most commonly affects the arms or legs, but can also occur in the chest wall, abdomen, neck and genitals.
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Do your muscles hurt with lymphoma?

The common clinical symptoms of primary skeletal muscle lymphoma are usually associated with muscle swelling, limb pain and edema, without any sign of heat and redness (5); in addition, this disease may occur as isolated lesions (11).
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Is there bone pain with lymphoma?

Bone pain is typically the first indication that lymphoma has metastasized to the bone. This pain may be intermittent — worsening and improving at different times. People with cancer-related bone pain often find that this symptom improves with physical activity or movement and worsens during the nighttime.
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Are there lymph nodes in back of thigh?

Lymph nodes are round, bean-shaped glands, and you have them throughout your body. There are clusters of them in places like your neck, under your arm, and in the crease between your thigh and your torso (where your leg begins). You can sometimes feel these clusters as little bumps, especially if they're swollen.
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What can be mistaken for lymphoma?

Conditions that non-Hodgkin Lymphoma is commonly misdiagnosed as include:
  • Influenza.
  • Hodgkin's lymphoma.
  • Cat scratch fever.
  • HIV.
  • Infections.
  • Mononucleosis.
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Does lymphoma show up in blood work?

Most types of lymphoma can't be diagnosed by a blood test. However, blood tests can help your medical team find out how lymphoma and its treatment are affecting your body. They can also be used to find out more about your general health.
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Does lymphoma cause hip pain?

Some differential diagnoses to consider in patients with hip pain include but are not limited to: labral tears, femoroacetabular impingement, iliopsoas tendinitis, adductor strain, greater trochanteric bursitis, arthritis, fracture, or malignancy. One such malignancy to consider is lymphoma.
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Can lymph nodes cause muscle pain?

Infected Lymph Node.

At all ages, it can be from a swollen lymph node. That can irritate and cause spasm of the neck muscle it lies against.
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Where does lymphoma usually start?

Lymphoma is cancer that begins in infection-fighting cells of the immune system, called lymphocytes. These cells are in the lymph nodes, spleen, thymus, bone marrow, and other parts of the body.
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How is lymphoma of the leg treated?

The treatment of choice is rituximab (Rituxan) along with systemic chemotherapy. Often the regimen called R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) is given, but other chemo combinations can also be used.
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Do lymphoma symptoms come and go?

When dealing with lymphoma, these symptoms may come and go and are sometimes referred to as 'B symptoms. ' These symptoms can include a persistent, chronic fever; unintended weight loss, and excessive sweating, especially at night (night sweats).
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How long can you live with untreated lymphoma?

] evaluated 52 and 80 biopsy-proven cases, respectively, of untreated Hodgkin lymphoma from 1910–1962. The median overall survival from Craft's series was 16.6 months, with a 3 year survival of 15.4%, and greater than 5 year survival of less than 6%.
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What is the most common and distinguishing early symptom of lymphoma?

The best way to find lymphoma early is to pay attention to possible signs and symptoms. One of the most common symptoms is enlargement of one or more lymph nodes, causing a lump or bump under the skin which is usually not painful. This is most often on the side of the neck, in the armpit, or in the groin.
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How long can you have lymphoma without knowing?

These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
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What blood test results indicate lymphoma?

Complete blood count (CBC).

This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
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Does lymphoma cause weakness in legs?

Lymphomas involving the brain or spinal cord may cause neurological symptoms such as confusion, numbness or weakness in the arms or legs. Lymphomas in the chest can cause cough, shortness of breath, or chest pain.
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