Does Izzie return?

That same year, Rhimes said there were no plans for Izzie to return, but a lot has changed since then. Izzie briefly appeared in season 16 in the sequence that explained why Alex Karev left Grey's Anatomy, though it was another actress taking the spot of Izzie.
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Does Izzie return in Season 12?

Katherine heigl on 'Grey's Anatomy' Return as Izzie in Season 12 | TVLine.
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Does Izzy come back in season 16?

Grey's Anatomy Season 16 saw the return of Izzie Stevens (Katherine Heigl) in the most unconventional way. The character rekindled her flame with Alex Karev (Justin Chambers).
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Does Izzie come back after leaving?

Izzie's time with cancer was rough, and it took a toll on her relationship with Alex. After she was fired from SGMW, she left Alex. Eventually, she did come back, wanting to reunite with Alex when she found out her cancer was gone.
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Does Burke come back?

While mentioned in passing throughout later seasons, Burke officially returns in the tenth season in order to conclude Cristina Yang's departure from the series.
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Alex and Izzie´s twins - Grey´s Anatomy 16x16 (Part 2)



Does Izzie meet her daughter?

10 Never Meeting Her Daughter

Later on, Izzie's daughter, now named Hannah, arrived at Seattle Grace as a leukemia patient in need of a bone marrow transplant. She is happy to help, and hopes to formally meet her child. Hannah objects to this, and Izzie never interacts with her in the timeline of the show.
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Does Izzie return in season 17?

Now, some viewers are hoping she will return after Patrick Dempsey (Derek Shepherd) and T.R. Knight (George O'Malley) reprised their roles in season 17. But, will Heigl come back to Grey's Anatomy in the future? Recently, the actor revealed the decision isn't up to her.
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Does Izzie and Alex come back?

Alex's and Izzy's returns in season 18 are even less likely than Cristina's. Both characters abruptly left the series in seasons 16 and 6 (respectively). Katherine Heigl's exit was a much-publicized account of offscreen disputes between her and Rhimes.
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Did Alex and Izzie have a baby?

In the March 5, 2020 episode, Grey's stunned viewers when it was revealed Alex had left Seattle to reunite with his former flame, Izzie, and they were happily raising their two young twins on a horse farm in Kansas.
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Why was Denny Duquette so rich?

Duquette, Denny's father. But Mr. Duquette wasn't just there to meet the woman his son so quickly fell in love with, he was there to deliver a gift. As it turns out, one of Denny's final actions was to ensure his fiancé received an $8.7 million check upon his death.
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What season does Izzie come back Greys?

Nevertheless, Izzie came back in the 12th episode of season 6, where she revealed that she was cancer-free and asked Alex to come back in her life.
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Who does Christina end up with?

Cristina Yang & Owen Hunt – After the shooting, Cristina and Owen decided to get married.
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Do Izzie and Alex get back together after season 6?

She was so angry that she just wrote him a letter and left (the irony of this form of breakup is not lost on us, Grey's fans). That was essentially the end of their relationship. Though Izzie did return later in Season 6 to try and rekindle things with Alex, he realized he deserved better than to be jerked around.
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Why did Karev leave Jo for Izzie?

Alex explained that Izzie used their frozen embryos and gave birth to their twins. He also realized he was still in love with his ex. So Alex chose to leave Jo for a life with Izzie and their children in Kansas.
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Does Alex leave Jo for Izzie?

The news that Alex had left Jo (Camilla Luddington) for Izzie was a shock to fans everywhere. When it was announced that Justin Chambers would be leaving the series, not many fans seemed to have considered the ending the writers planned for Alex would be an ending that most would not like.
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Is Callie coming back to GREY's season 18?

After the plethora of fan-favorites who returned in Grey's Anatomy Season 17, it's no surprise that season 18 is shaping up to be the same, and it looks like Calzona could be next on the list. Sara Ramirez told news outlets in December 2021 that they would “absolutely” return to the series.
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Is Alex coming back to GREY's Anatomy season 19?

The Grey's Anatomy Season 19 Plot

Since Astin likely won't return, there's also the possibility of a Jo and Link romance, especially now that the former admitted to being in love with her longtime friend.
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Is season 18 of Grey's Anatomy the last season?

Depending on the events of the Season 18 finale, the entire main cast are expected to return for Grey's Anatomy Season 19.
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Who comes back in season 18 of Grey's anatomy?

Jesse Williams and Sarah Drew are both returning to the world of Grey's Anatomy for the season 18 finale, which will air May 26, EW has confirmed.
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Who was the father of Izzy's baby GREY's anatomy?

The news that the beloved pediatric surgeon had run off to be with Izzie was first disclosed in a letter read by Meredith Grey (Ellen Pompeo). In another shocking plot twist, it was revealed that Izzie gave birth to twins and Alex is the father!
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Did Izzie give a baby up for adoption?

Izzie revealed to a patient that she got pregnant at 16, but gave her daughter up for adoption. Typically you would have to be 31 or 32 when beginning an internship after med school etc, which would make her daughter 16. However, Izzie tells her patient that her daughter is 11, which would make Izzie only 26 or 27.
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What does Izzie do with the 8 million dollars?

Izzie is the sole beneficiary of Denny's will, inheriting $8.7 million. She uses the money to open a free clinic at the hospital: the Denny Duquette Memorial Clinic.
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What episode does Dr Burke come back?

On Grey's Anatomy season 10, episode 22, “We Are Never Getting Back Together,” Preston Burke will make his return to the show during a critical time in Cristina's career. At a point in her life where she's unsure of where she's at – he'll arrive with an opportunity.
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Does Meredith get Alzheimer's?

Ellis suffered from Alzheimer's and passed away as a result, and in Grey's Anatomy season 9, Meredith tested positive for several genetic markers for Alzheimer's – and as this disease develops slowly and early in life, so when it's diagnosed it's too late to treat it, a theory (via EW) suggests Grey's Anatomy will end ...
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