Does Chagas disease cause weight loss?

GI symptoms, such as dysphagia, odynophagia, weight loss, prolonged constipation.

What is the initial symptom of Chagas disease?

Symptoms may include swelling at the infection site, fever, fatigue, body aches, rash and nausea.

How does Chagas disease affect the body?

Symptoms of Chagas disease in the acute phase (the first few weeks or months) are: Mild, flu-like symptoms, such as fever, fatigue, body aches, and headaches. Rash. Loss of appetite.

Can you have Chagas and not know it?

Many people may remain asymptomatic for life and never develop Chagas-related symptoms. However, an estimated 20–30% of infected people will develop severe and sometimes life-threatening medical problems over the course of their lives. A dilated esophagus or colon, leading to difficulties with eating or passing stool.

What are the symptoms of Chagas cardiomyopathy?

(See "Chagas disease: Chronic Trypanosoma cruzi infection".) Patients with CCC may be asymptomatic or present with symptoms such as dyspnea on exertion, fatigue, palpitations, dizziness, syncope, chest pain (atypical or angina), and edema.

KILLER DISEASES | How Chagas Disease Affects the Body

What are 4 signs of cardiomyopathy?

What organ does Chagas disease target?

Clinical course

Chronic infections are asymptomatic in two thirds of the human population. Chronic Chagas disease affects mostly the heart and the digestive tract.

Can blood test detect Chagas?

The diagnosis of Chagas disease can be made by observation of the parasite in a blood smear by microscopic examination. A thick and thin blood smear are made and stained for visualization of parasites.

How do you get tested for Chagas?

Anyone who suspects that they may have Chagas disease should ask their doctor to order this test. Patients who test positive for the infection should have a cardiac check-up. This is done using radiography, an electrocardiogram and occasionally an echocardiogram.

How do they test for Chagas disease in humans?

Commonly used techniques include enzyme-linked immunosorbent assay (ELISA) and immunofluorescent antibody test (IFA).

What are the neurological symptoms of Chagas disease?

In the chronic phase, it presents as neuritis that results in altered tendon reflexes and sensory impairment, and is reported in up to 10% of the patients. Isolated cases of central nervous system involvement can also include dementia, confusion, chronic encephalopathy and sensitive and motor deficits.

Can you recover from Chagas disease?

Treatment. To kill the parasite, Chagas disease can be treated with benznidazole or nifurtimox. Both medicines are nearly 100% effective in curing the disease if given soon after infection at the onset of the acute phase, including the cases of congenital transmission.

What is the major concern for chronic Chagas disease patients?

Nearly 30% of chronically-infected patients become symptomatic, often with a latency of 10-30 years, developing life-threatening complications. Of those, nearly 90% develop Chagas heart disease, while the others manifest gastrointestinal disease and neuronal disorders.

How rare is Chagas disease?

Chagas disease is common in parts of Mexico, Central America, and South America where an estimated 8 million people are infected.

Does Chagas affect the brain?

The involvement of the central nervous system (CNS) during human acute and chronic Chagas disease (CD) has been largely reported. Meningoencephalitis is a frequent finding during the acute infection, while during chronic phase the CNS involvement is often accompanied by behavioral and cognitive impairments.

What is the drug of choice for Chagas disease?

* Benznidazole is FDA-approved for the treatment of Chagas disease (American trypanosomiasis) caused by Trypanosoma cruzi in pediatric patients 2–12 years of age.

How much is a Chagas test?

Results: The cost of Chagas' disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively.

When should you get tested for Chagas?

Indications for Testing

Laboratory testing for Chagas disease is indicated in individuals who are at risk when clinical findings point to acute- or chronic-phase infection.

Can you cure chronic Chagas?

Once Chagas disease reaches the chronic phase, medications won't cure the disease. But, the drugs may be offered to people younger than age 50 because they may help slow the progression of the disease and its most serious complications.

What does Chagas do to the heart?

Chagas cardiomyopathy represents the most frequent and serious complication of chronic Chagas disease, affecting about 20-30% of patients, potentially leading to heart failure, arrhythmias, thromboembolism, stroke and sudden death.

Who is the most common victim of Chagas?

People who have Chagas disease can be found anywhere in the world. However, transmission of the disease by kissing bugs (vectorborne transmission), only occurs in the Americas. Most people with Chagas disease became infected in rural areas of Mexico, Central America, and South America.

How common is Chagas in us?

More than 5 million people worldwide have Chagas disease. In the United States, there are estimated to be at least 300,000 cases of chronic Chagas disease among people originally from countries of Latin America where Chagas disease is endemic.

Is Chagas disease autoimmune?

In fact, the first evidence of autoimmunity in CD was presented by Cossio and collaborators in 1974 (61), who reported antibodies in sera of chagasic patients that reacted with endocardium, interstitium, and heart blood vessels but were absent in healthy individuals and in patients with non-chagasic cardiomyopathy.

What are the first signs of a weak heart?

What does heart failure fatigue feel like?

Tiredness, fatigue

...a tired feeling all the time and difficulty with everyday activities, such as shopping, climbing stairs, carrying groceries or walking. The heart can't pump enough blood to meet the needs of body tissues.