Can you take Robitussin with antidepressants?

Antidepressants and dextromethorphan or pseudoephedrine
It's generally considered safe to take antidepressants while taking cold medicine. “However, cold/flu medications that contain dextromethorphan may increase the risk of a rare side effect called serotonin syndrome when taken with SSRIs and SNRIs,” Dr. Carter says.
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Does Robitussin interact with antidepressants?

When people combine dextromethorphan (the "DM" in Robitussin DM and similar products) with Prozac-like drugs, the result can be "serotonin syndrome." Symptoms can include anxiety, confusion, fever, sweating, agitation, muscle twitching, tremor and heart palpitations.
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Can you take Robitussin and SSRI?

How the interaction occurs: Your antidepressant may cause your body to process dextromethorphan more slowly. In addition, both medicines can increase the level of serotonin in your body.
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What medications interact with Robitussin?

There may be an interaction between dextromethorphan and any of the following:
  • abiraterone acetate.
  • amiodarone.
  • amphetamines (e.g., dextroamphetamine, lisdexamphetamine)
  • antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone)
  • asunaprevir.
  • bromocriptine.
  • bupropion.
  • buspirone.
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Can you take Robitussin with anxiety medication?

Interactions between your drugs

Using ALPRAZolam together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
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How do antidepressants work? - Neil R. Jeyasingam



Can you take cold medicine with antidepressants?

Can You Combine Antidepressants & Cold Medicine? The short answer is: you can, but it's not recommended because of the risks. The combination of antidepressants and cold medicine may increase serotonin levels, which could cause Serotonin Syndrome.
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Can I take Robitussin while on Zoloft?

Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or ...
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What should you not mix with Robitussin?

Avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication.
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When should you not take Robitussin?

You should not use Robitussin Cold and Cough if you are allergic to dextromethorphan, guaifenesin, or pseudoephedrine. Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur.
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Is Robitussin good for dry cough?

Get relief from your dry cough, chest congestion, and stuffy nose, while soothing your throat. This syrup includes both a cough suppressant to quiet coughs, and an expectorant to loosen mucus and phlegm, plus a decongestant to relieve nasal congestion.
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Can Robitussin DM cause anxiety?

Dextromethorphan: If you've got a brand-name medicine that's followed by “DM”, you've probably got dextromethorphan . It works as a cough suppressant and can cause dizziness, lightheadedness, nervousness, and restlessness.
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What decongestant can I take with antidepressant?

Official answer. A nasal decongestant and acetaminophen combination tablet or a nasal decongestant spray may be of benefit, and are safe.
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Can I take Robitussin while on Prozac?

Using diphenhydrAMINE together with FLUoxetine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
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Can antidepressants cause a cough?

Diarrhea. Drowsiness. Increased sweating or urination. Cold symptoms such as sneezing, sore throat, and cough.
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Why does dextromethorphan cause serotonin syndrome?

Tricyclic antidepressants and opioids have reported cases of serotonin syndrome. Both dextromethorphan and the SSRI escitalopram are metabolised by CYP2D6, potentiating the serotonin reuptake effect. Our patient was found with altered mental status but was awake and agitated in the ED prior to receiving lorazepam.
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What are the symptoms of serotonin syndrome?

Signs and symptoms include:
  • Agitation or restlessness.
  • Insomnia.
  • Confusion.
  • Rapid heart rate and high blood pressure.
  • Dilated pupils.
  • Loss of muscle coordination or twitching muscles.
  • High blood pressure.
  • Muscle rigidity.
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What are Robitussin side effects?

Dizziness, headache, nausea, nervousness, or trouble sleeping may occur. If any of these effects last or get worse, contact your doctor or pharmacist promptly. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects.
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What will help a dry cough?

How can I treat a dry cough and tight chest?
  1. Drink plenty of liquids to stay hydrated. Try hot tea or water with honey and lemon to soothe irritated airways.
  2. Suck on cough drops or hard candies. Sucking on a hard lozenge promotes saliva production that soothes the throat. ...
  3. Take a spoonful of honey. ...
  4. Use a humidifier.
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What's the difference between Robitussin and Robitussin DM?

Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products. Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
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Does Robitussin DM make your heart race?

Do not take more than the recommended amount of dextromethorphan. If you experience muscle twitching, tremors, shivering or stiffness, fever, heavy sweating, heart palpitations, restlessness, confusion, agitation, trouble with coordination, or severe diarrhea contact your doctor right away.
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How long does it take for Robitussin to start working?

Dextromethorphan's medicinal effects typically begin after 15 and 30 minutes, reach their maximum around 2 to 3 hours, and end at or before 6 hours. Like any medication, there are potential side effects, including constipation, drowsiness, nausea, vomiting, dizziness, sedation, nervousness, and confusion.
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What drugs interact with dextromethorphan?

What Other Drugs Interact with Dextromethorphan?
  • isocarboxazid.
  • phenelzine.
  • procarbazine.
  • rasagiline.
  • safinamide.
  • selegiline.
  • tranylcypromine.
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Can I take Prozac and cough medicine?

Answer: Many antidepressants, including fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft), can interact with cold medicines containing the cough suppressant dextromethorphan (DM) or the antihistamine chlorpheniramine (British Journal of Clinical Pharmacology, December 2010).
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How common is serotonin syndrome?

Cases of serotonin syndrome resulting in hospitalization or death are rare. Most cases do not require medication intervention, but can be managed by stopping the drug or decreasing the dose. Mild toxicity appears to be rare but is likely under-reported, unrecognized, or confused with other syndromes.
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What cough medicine does not contain dextromethorphan?

An example of a medication available that doesn't include DXM is plain Mucinex (be sure to grab the box that says Mucinex, and not Mucinex DM, which does contain DXM), an expectorant that contains the ingredient guaifenesin.
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