Can you take prednisone for 20 years?

Official answer. There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term.
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What happens if you take prednisone for years?

Long-term use of prednisone may lead to bone loss and osteoporosis. It can cause changes in the distribution of body fat which together with fluid retention and weight gain may give your face a moon-like appearance. Stretch marks, skin thinning, and excessive facial hair growth are also not uncommon.
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Can prednisolone be taken long term?

How long to take it for. This depends on your health problem or condition. You may only need a short course of prednisolone for up to 1 week. You may need to take it for longer, even for many years or the rest of your life.
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Can you stay on steroids for years?

Some people are prescribed steroid medicines on an ongoing basis for the treatment of long-term conditions. Taking steroids long term is helpful to treat conditions associated with inflammation, but ongoing steroid use can cause side effects. Prednisone is the most commonly prescribed steroid.
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Can you be on prednisone for life?

Official answer. There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term.
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The Bad of Corticosteroids | Johns Hopkins



How long is considered long term prednisone use?

Treatment extending longer than three months is considered long term and results in the majority of severe side effects. When steroids are used for short durations of a few days or weeks, they are relatively safe.
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How long can I take prednisone for arthritis?

Continue to take prednisone tablets regularly until your doctor tells you otherwise. You may need to take them for several months, or even longer. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually if this is necessary.
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What is the downside of taking prednisone?

Common side effects of daily low dose prednisone include elevated blood pressure, swelling, changes in blood sugar, increased appetite, weight gain, insomnia, osteoporosis (thinning of bones), irregular menstrual periods, and mood changes.
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How often is it safe to take prednisone?

How should this medicine be used? Prednisone comes as a tablet, delayed-release tablet, as a solution (liquid), and as a concentrated solution to take by mouth. Prednisone is usually taken with food one to four times a day or once every other day.
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Is it OK to take 5mg of prednisone daily?

The data document that prednisone at doses <5 mg/day over long periods appears acceptable and effective for many patients with RA at this time. Further clinical trials and long-term observational studies are needed to develop optimal treatment strategies for patients with RA with low-dose prednisone.
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Is 20 mg of prednisone a lot?

Official answer. The starting dose of prednisone may be between 5 mg to 60 mg per day. A dose above 40 mg per day may be considered a high dose.
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What are the side effects of taking 5mg of prednisone daily?

Nausea, vomiting, loss of appetite, heartburn, trouble sleeping, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
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Is there an alternative for prednisone?

They include methotrexate, Arava, and the anti-TNF drugs such as Enbrel, Humira, and Remicade. These are very strong drugs as well and must be used with caution, but sometimes they can have good effects when taken in small amounts or as a short-term alternative to prednisone.
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Can prednisone cause long term effects?

Occurrence is often associated with dose and duration of therapy; long-term effects include HPA suppression, Cushingoid appearance, cataracts and increased intraocular pressure/glaucoma, osteoporosis and vertebral compression fractures.
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What are the most serious side effects of prednisone?

High blood pressure. Problems with mood swings, memory, behavior, and other psychological effects, such as confusion or delirium. Upset stomach. Weight gain, with fat deposits in your abdomen, your face and the back of your neck.
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What vitamins should not be taken with prednisone?

Reduce Side Effects
  • Calcium and Vitamin D. Oral corticosteroids reduce absorption of calcium and interfere with the activation and metabolism of the vitamin, increasing the risk of bone loss. ...
  • Fiber. Propoxyphene may cause gastrointestinal (GI) upset. ...
  • Chromium.
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Does prednisone lose effectiveness over time?

You could expect a dose of prednisone to stay in your system for 16.5 to 22 hours. The elimination half life of prednisone is around 3 to 4 hours. This is the time it takes for your body to reduce the plasma levels by half. It usually takes around 5.5 half lives for a drug to be completely eliminated from your system.
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What are the worst side effects of prednisone 20mg?

Serious side effects of prednisone may include:
  • Allergic reactions.
  • Cardiovascular problems.
  • Decrease in bone density.
  • Eye damage.
  • Fetal toxicity.
  • High blood sugar.
  • Increased risk of GI perforation.
  • Increased risk of infection.
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Why does prednisone make me feel so good?

Prednisone affects areas of the brain that manage the regulation of different neurotransmitters, including serotonin and dopamine — the “feel-good” hormones. Feeling happy is a great side effect some people feel with prednisone. Other responses are more menacing, especially if you don't know what to expect.
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Is 2.5 mg of prednisone a lot?

Dosage reductions should not exceed 5-7.5mg daily during chronic treatment. Allergic and skin disorders Initial doses of 5-15mg daily are commonly adequate. Collagenosis Initial doses of 20-30mg daily are frequently effective. Those with more severe symptoms may require higher doses.
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Is prednisone good for osteoarthritis?

Treatment with 10 mg prednisolone for 6 weeks is efficacious and safe for the treatment of patients with painful hand osteoarthritis and signs of inflammation. The results of our study provide clinicians with a new short-term treatment option for patients with hand osteoarthritis who report a flare-up of their disease.
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Is 40mg of prednisone a lot?

Prednisone is the oral tablet form of steroid most often used. Less than 7.5 mg per day is generally considered a low dose; up to 40 mg daily is a moderate dose; and more than 40-mg daily is a high dose. Occasionally, very large doses of steroids may be given for a short period of time.
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Does turmeric work like prednisone?

After 12, 24 and 48 hours, curcumin does not have the same anti-inflammatory effects when compared to prednisone. After 48 hours, prednisone is more effective than curcumin in reducing the inflammatory infiltrate regardless of the dose of prednisone used.
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Are there any over the counter steroids like prednisone?

Some of the more commonly prescribed corticosteroids are cortisone, hydrocortisone, prednisone, prednisolone, and methylprednisolone. Most corticosteroids are available by prescription only (with the exception of over-the-counter nasal sprays or topical steroids like hydrocortisone 1%).
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What is a natural substitute for steroids?

Creatine. Currently, creatine is the only natural steroid that the Food and Drug Administration (FDA) approve for short-term use in healthy adults aged over 18 years to improve athletic performance. Several studies have found that using creatine for 5–7 days can significantly increase: strength.
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