Can you still have a stroke when taking clopidogrel?

If you stop taking clopidogrel, your blood will start clotting at the same rate as before you started taking it, usually within 5 days of stopping the medicine. This means you may be at increased risk of serious problems like heart attacks or strokes.
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Can you have a stroke while on blood thinners?

Unfortunately, the blood thinners used to prevent such blood clots can increase the risk of bleeding in the brain, a cause of hemorrhagic stroke.
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How much does clopidogrel reduce stroke risk?

The risk reduction was largely due to a significant reduction of ischemic strokes, with rates of 1.9% versus 2.8% per year in the clopidogrel and control groups, respectively (RR, 0.68; 95% CI, 0.57–0.80).
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Can you still get blood clots on clopidogrel?

If you're taking Plavix, you were probably started on the drug because you had an increased risk of having blood clots. Shortness of breath can be a sign of a dangerous side effect called thrombotic thrombocytopenic purpura (TTP). With TTP, blood clots are formed throughout your body.
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How do you know if clopidogrel is working?

Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.
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How Does Clopidogrel (Anti-platelets) Work? (+ Pharmacology)



Why do some people not respond to clopidogrel?

Some people with clopidogrel resistance have a reduced ability to convert the drug to its active form because of a polymorphism in one copy of the CYP2C19 gene that results in decreased enzyme activity. These individuals are described as intermediate metabolizers.
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Do you need regular blood tests with clopidogrel?

Clopidogrel doesn't require regular blood test monitoring, but it affects platelet function and bleeding times for up to 7–10 days. You may need to avoid elective dental work and elective operations while taking aspirin or clopidogrel due to risks of bleeding.
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Can a blood clot move while on blood thinners?

Blood thinners.

Blood thinners are also used to help prevent clots after a stroke or pulmonary embolism (when a blood clot travels to an artery in your lungs). Blood thinners don't dissolve the clot, but they can stop it from getting bigger and keep new ones from forming. That gives your body time to break up the clot.
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Can you still get blood clots on blood thinners?

Yes. Medications that are commonly called blood thinners — such as aspirin, warfarin (Jantoven), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa) and heparin — greatly decrease your risk of blood clotting. But they don't prevent blood clots completely.
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How do you know if you have blood clots?

Symptoms of a blood clot include: throbbing or cramping pain, swelling, redness and warmth in a leg or arm. sudden breathlessness, sharp chest pain (may be worse when you breathe in) and a cough or coughing up blood.
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How long is it safe to take clopidogrel?

Clopidogrel and low-dose aspirin

The key question for your doctor is whether the benefits outweigh the extra risk. This combination treatment is prescribed for a limited period of time, usually up to a maximum of 12 months.
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Which is a better blood thinner clopidogrel or aspirin?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).
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What is a breakthrough stroke?

'Aspirin failure' is defined as breakthrough stroke or TIA in patients taking aspirin. The reasons for aspirin failure are unclear, although insufficient platelet inhibition by aspirin is considered an important reason.
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Do blood thinners stop strokes?

Anticoagulants, often called blood thinners, are medications to prevent these strokes. They prevent harmful blood clots from forming. They also stop helpful blood clots, making you more likely to bleed. While rare, bleeding can be a serious problem.
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How effective are blood thinners at preventing strokes?

Blood thinners are among the most effective means of preventing a stroke. However, all blood thinners are known to have potential side effects, even over the counter blood thinners. While you are taking blood thinners, it is important that you are able to recognize the side effects.
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Can thin blood cause a stroke?

However, if the drug makes the blood too thin, it can increase the risk of brain hemorrhage, a type of stroke caused by bleeding in the brain.
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How long does it take for a blood clot to dissolve with blood thinners?

Blood clots can take weeks to months to dissolve, depending on their size. If your risk of developing another blood clot is low, your doctor may prescribe you 3 months of anticoagulant medication, as recommended by the American Heart Association . If you're at high risk, your treatment may last years or be lifelong.
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What are the symptoms of internal bleeding from blood thinners?

Signs of excessive bleeding can include:
  • passing blood in your urine.
  • passing blood when you poo or having black poo.
  • severe bruising.
  • prolonged nosebleeds (lasting longer than 10 minutes)
  • vomiting blood or coughing up blood.
  • sudden severe back pain.
  • difficulty breathing or chest pain.
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Is walking good for blood clots?

The Importance of Exercise if You Have DVT

Aerobic activity -- things like walking, hiking, swimming, dancing, and jogging -- can also help your lungs work better after a pulmonary embolism. Studies show that exercise also can improve symptoms of DVT, including swelling, discomfort, and redness.
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What is the safest blood thinning medication?

Safer Blood-Thinning Drugs to Prevent Stroke

The newer medications are Pradaxa (dabigatran), Xarelto (rivaroxaban), Eliquis (apixaban), and most recently Savaysa (edoxaban) — which work by preventing pooled blood in the heart from clotting. Unlike warfarin, the newer drugs are safer and easier for patients to use.
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What does a blood clot feel like?

The feeling can range from a dull ache to intense pain. You may notice the pain throbs in your leg, belly, or even your arm. Warm skin. The skin around painful areas or in the arm or leg with the DVT may feel warmer than other skin.
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How long does it take for a blood clot to travel through the body?

Living with DVT

It takes about 3 to 6 months for a blood clot to go away. During this time, there are things you can do to relieve symptoms. Elevate your leg to reduce swelling. Talk to your doctor about using compression stockings.
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What are the most common side effects of clopidogrel?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • excessive tiredness.
  • headache.
  • dizziness.
  • nausea.
  • vomiting.
  • stomach pain.
  • diarrhea.
  • nosebleed.
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What should you not take with clopidogrel?

Clopidogrel may interact with other medications
  • Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
  • Stomach acid drugs (proton pump inhibitors) ...
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
  • Blood thinners.
  • Drugs used to treat depression. ...
  • Salicylates (aspirin) ...
  • Opioids.
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What vitamins should be avoided when on blood thinners?

If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K. Blood thinners are often prescribed for people at risk for developing harmful blood clots.
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