Can you mix and match the vaccines for your mRNA (Pfizer or Moderna) primary vaccination series?

Booster shots have now been approved for all three of the COVID-19 vaccines available in the U.S. And the Centers for Disease Control and Prevention's (CDC) new guidelines say that people who are fully vaccinated against the coronavirus can now mix and match their immunizations when seeking a booster shot.

Can you mix COVID-19 vaccines?

Mixing and matching is OK for boosters Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters.

Can you mix and match COVID-19 booster doses?

The FDA has authorized the use of mix-and-match booster doses for currently available COVID-19 vaccines based on the results of a NIAID-supported study.

Should the booster shot be the same as the first two shots?

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The FDA has authorized three vaccine boosters — Pfizer-BioNTech, Moderna and Janssen/Johnson & Johnson — and determined that it is safe for individuals to receive a COVID-19 vaccine booster or additional dose that is a different brand than the initial dose or doses.

Can I choose which COVID-19 vaccine I get?

Yes, depending on your age, you can choose which COVID-19 vaccine to get. For adults ages 18 years and older, the mRNA COVID-19 vaccines (Pfizer-BioNTech or Moderna) are preferred over Johnson & Johnson’s Janssen (J&J/Janssen) COVID-19 vaccine. You may get J&J/Janssen COVID-19 vaccine in some situations.

Currently, Pfizer-BioNTech COVID-19 vaccine is the only COVID-19 vaccine available to children ages 5 through 17 years old.

Learn more about your COVID-19 vaccination, including how to find a vaccination location, what to expect at your appointment, and more.

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What is the best vaccine for COVID-19?

In most situations, mRNA COVID-19 vaccines (Pfizer-BioNTech or Moderna) are preferred over the J&J/Janssen COVID-19 vaccine for primary and booster vaccination due to the risk of serious adverse events.

Is it safe for women to take the Moderna or Pfizer COVID-19 vaccine?

The Centers for Disease Control and Prevention (CDC) recommend most adult women receive a two-shot primary series of either the Pfizer-BioNTech or Moderna mRNA COVID-19 vaccines, followed by a booster dose at least five months after the last primary dose.

How long after the COVID-19 booster is it effective?

The first COVID-19 booster shot is now in the rearview mirror for millions of Americans -- for the 28% who got it, at least -- but new data finds it's less effective after about 4 months. The CDC has already recommended a second booster for immunocompromised people.
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Is it recommended to take booster shot after primary J&J COVID-19 vaccine?

If you are age 18 or older, have been given one dose of the Janssen/Johnson & Johnson COVID-19 vaccine and it's been at least 2 months, you should get a single booster dose. The Pfizer-BioNTech or Moderna COVID-19 vaccine boosters are preferred in most situations.

Are side effects of the COVID-19 booster shot worse?

November 08, 2021 If you experienced side effects when you were vaccinated initially, you may wonder if you'll have any noticeable symptoms in response to your booster shot. While you may have some side effects, they should be no worse than what you experienced originally and may well be milder.

Do COVID-19 boosters use the same ingredients as existing vaccines?

Yes. COVID-19 boosters are the same ingredients (formulation) as the current COVID-19 vaccines. However, in the case of a Moderna COVID-19 vaccine booster, the dose is half of the amount of the vaccine people get for their primary series.

Are there any second COVID-19 vaccine booster available?

Recently, the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) authorized a second booster shot of the Pfizer-BioNTech and Moderna vaccines for everyone 50 and older and for people with certain conditions that make them immunocompromised.

Can you get another vaccine if you get the Johnson and Johnson COVID-19 vaccine?

If you got J&J as your initial vaccine and are 18 or older, you are eligible for a booster shot two months later, regardless of which one you choose (you're eligible six months later if you had Moderna or Pfizer-BioNTech as your primary series).

How do I know if I’ve been fully vaccinated if I was vaccinated in another country?

If you have received all recommended doses of a COVID-19 vaccine that has been authorized or approved by the U.S. Food and Drug Administration (FDA) or is listed for emergency use by the World Health Organization (WHO), then you are considered to be fully vaccinated.

Can you get COVID-19 from sex?

All close contact (within 6 feet or 2 meters) with an infected person can expose you to the virus that causes coronavirus disease 2019 (COVID-19) — whether you're engaged in sexual activity or not.

What medicine should you not take before COVID-19 vaccination?

It is not recommended you take over-the-counter medicine (such as ibuprofen, aspirin, or acetaminophen) before vaccination for the purpose of trying to prevent vaccine-related side effects. It is not known how these medications might affect how well the vaccine works.

Should you get a booster shot if you have COVID-19 symptoms?

Key takeaways: The CDC recommends booster shots — even in people who had a breakthrough case of COVID-19. If you have active symptoms of a COVID-19 infection, you shouldn't get a booster shot until your symptoms have fully resolved.

Should I still get the COVID-19 booster shot if I have a cold and test negative for COVID-19?

What if you have mild cold or flu-like symptoms (stuffy nose, headache) and test negative for COVID-19? You can still get boosted, according to the CDC. But be sure to wear a mask to the vaccine site in order to protect yourself and others.

Is it safe to take the Johnson and Johnson COVID-19 vaccine?

For many people, the benefits of the Johnson & Johnson vaccine outweigh the risks. It's effective at preventing severe illness, hospitalization, and death from COVID-19, and it's the only single-dose option available. However, you'll still need to get a booster shot 2 months later.

When does immunity start after the Pfizer COVID-19 vaccine?

Data released by the U.S. Food and Drug Administration (FDA) show that COVID-19 protection from the Pfizer/BioNTech vaccine was demonstrated in the clinical trials at about 14 days after the first shot. The FDA said some level of immunity may start sooner, but how much is not certain.

How long do COVID-19 vaccines last?

It is normal for virus-fighting antibodies—such as those that are stimulated by a COVID-19 vaccine—to wane over time. Monitoring antibody levels in the blood is one way to measure vaccine efficacy and research has found that protection remains high for six months after the second shot of a Pfizer or Moderna vaccine.

How long does it take for immunity to wane after receiving the COVID-19 vaccine?

A study published by the U.S. Centers for Disease Control and Prevention found that immunity against severe COVID-19 begins to wane four months after receiving a so-called "booster" third dose of the Pfizer or Moderna vaccines.

What are some of the side effects of the COVID-19 vaccine in women?

COVID-19 vaccines can cause swelling in your lymph nodes or arm. Women who have been vaccinated against COVID-19 can develop enlarged underarm lymph nodes on the same side where they had the shot. It's more common for this to happen after boosters and additional doses.

How does the COVID-19 vaccine affect menstruation?

Women who received COVID-19 vaccines had a less than one-day increase in the length of their menstrual cycles around the time of their doses. The findings suggest that women may have a slightly longer menstrual cycle after COVID-19 vaccination, but the change is temporary and within the range of normal variation.

Has anyone had severe reactions to the Moderna COVID-19 vaccine?

Monitoring of the Moderna COVID-19 vaccine has found 10 cases of anaphylaxis after the administration of 4,041,396 first doses of the Moderna COVID-19 vaccine. In 9 out of these 10 cases of anaphylaxis, the recipient of the vaccine had onset of symptoms within 30 min of administration.