Can you mix and match Pfizer and Moderna COVID-19 vaccine?

Mixing and Matching COVID-19 Vaccine Booster Doses. The FDA has authorized the use of mix-and-match booster doses for currently available COVID-19 vaccines based on the results of a NIAID-supported study.
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Can you mix COVID-19 vaccines?

Mixing and matching is OK for boosters Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters.
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Can you mix and match the vaccines for your mRNA (Pfizer or Moderna) primary vaccination series?


No, vaccines used for the primary vaccination series should be same. However, if the mRNA vaccine product given for the first two doses is not available or is unknown, either Pfizer-BioNTech or Moderna COVID-19 vaccine (mRNA COVID-19 vaccines) may be administered.

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Can I choose which COVID-19 vaccine I get?

Yes, depending on your age, you can choose which COVID-19 vaccine to get. For adults ages 18 years and older, the mRNA COVID-19 vaccines (Pfizer-BioNTech or Moderna) are preferred over Johnson & Johnson’s Janssen (J&J/Janssen) COVID-19 vaccine. You may get J&J/Janssen COVID-19 vaccine in some situations.

Currently, Pfizer-BioNTech COVID-19 vaccine is the only COVID-19 vaccine available to children ages 5 through 17 years old.

Learn more about your COVID-19 vaccination, including how to find a vaccination location, what to expect at your appointment, and more.

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Should I get the flu vaccine and the COVID-19 vaccine at the same time?

Even though both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine: If you haven't gotten your currently recommended doses of COVID-19 vaccine, get a COVID-19 vaccine as soon as you can, and ideally get a flu vaccine by the end of October.
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Can you get COVID-19 and the flu at the same time?

Yes. It is possible have flu, as well as other respiratory illnesses, and COVID-19 at the same time. Health experts are still studying how common this can be. Some of the symptoms of flu and COVID-19 are similar, making it hard to tell the difference between them based on symptoms alone.
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What medicine should you not take before COVID-19 vaccination?


It is not recommended you take over-the-counter medicine (such as ibuprofen, aspirin, or acetaminophen) before vaccination for the purpose of trying to prevent vaccine-related side effects. It is not known how these medications might affect how well the vaccine works.

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Is there a difference between the Moderna COVID-19 booster and Moderna third shot?


In the case of Moderna, the booster dose is only half of the original dose. Unlike boosters, third/additional doses of COVID-19 vaccines are for people who received the complete starter series of vaccines but then their immune systems didn't have a good enough response.

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Is it safe to take the Moderna, Pfizer-BioNTech, or J&J COVID-19 vaccine during pregnancy?

No safety concerns were found in animal studies: Studies in animals receiving a Moderna, Pfizer-BioNTech, or Johnson & Johnson (J&J)/Janssen COVID-19 vaccine before or during pregnancy found no safety concerns in pregnant animals or their babies.
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How do I know if I’ve been fully vaccinated if I was vaccinated in another country?

If you have received all recommended doses of a COVID-19 vaccine that has been authorized or approved by the U.S. Food and Drug Administration (FDA) or is listed for emergency use by the World Health Organization (WHO), then you are considered to be fully vaccinated.
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Are egg products used in COVID-19 vaccines?

The COVID-19 vaccines currently authorized by the FDA are not manufactured using egg products or egg culture. See COVID-19 vaccines for more information.
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Can you get another vaccine if you get the Johnson and Johnson COVID-19 vaccine?


If you got J&J as your initial vaccine and are 18 or older, you are eligible for a booster shot two months later, regardless of which one you choose (you're eligible six months later if you had Moderna or Pfizer-BioNTech as your primary series).

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Do mRNA COVID-19 vaccines cause heart inflammation?


These cases typically occur in male adolescents and young adults after the second dose, and within a week of vaccination. It is important to seek medical care if symptomatic (chest pain, shortness of breath, having a fast beating, fluttering, or pounding heart).

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How long does COVID-19 rebound last?

So far there have been no reports of severe illness in those who have experienced covid rebound, and most people seem to recover and stop testing positive around three days later without needing additional covid-19 treatment.
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How often can you take Paxlovid?

“With Paxlovid, you take three pills, twice a day, for a total of five days," says Rachel Kenney, a pharmacist at Henry Ford Health. "It helps your body fight off the virus, preventing it from replicating before it becomes serious.”
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How long does COVID-19 rebound usually last?

How long will a rebound last? In the cases that have been described, rebound symptoms improved and/or positive tests became negative within 3 days for most people.
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Is the COVID-19 vaccine safe for pregnancy?

Vaccination is recommended for pregnant women to prevent COVID-19, including severe illness and death. COVID-19 vaccination is safe and effective when administered during pregnancy
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What can you tell us about pregnancy after receiving the Pfizer COVID-19 shot?


What can you tell us about that? Results from published studies suggest there is no increased risk of first trimester pregnancy loss for patients who receive any of the three vaccines that currently have emergency use authorization: Pfizer, Moderna and Johnson & Johnson-Janssen.

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What are some of the risks of having COVID-19 while pregnant?


Effect on Pregnancy Outcomes. For example, COVID-19 during pregnancy increases the risk of delivering a preterm (earlier than 37 weeks) or stillborn infant. People with COVID-19 during pregnancy may also be more likely to have other pregnancy complications.

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When should you usually get a COVID-19 booster vaccine?

1st Booster: Most people, at least 5 months after the final dose in the primary series. People who are moderately or severely immunocompromised, at least 3 months after the final dose in the primary series.
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Is there an authorized booster for the Moderna COVID-19 vaccine?


The FDA-authorized Pfizer-BioNTech COVID-19 Vaccine and the FDA-approved Comirnaty can be used to provide the authorized booster dose(s). Similarly, the FDA-authorized Moderna COVID-19 Vaccine and the FDA-approved Spikevax are authorized to provide the authorized booster dose(s).

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How long does the protection from Pfizer and Moderna's COVID-19 booster vaccine last?


The most recent research from the CDC suggests that protection from the Pfizer and Moderna COVID-19 vaccines starts to fade around 4 months after a booster dose.

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What are some medications that are safe to take with the COVID-19 vaccine?

Taking one of the following medications is not, on its own, a reason to avoid getting your COVID-19 vaccination:

• Over-the-counter medications (non-prescription)
• Non-steroidal anti-inflammatory drugs (NSAIDs) (naproxen, ibuprofen, aspirin, etc.)
• Acetaminophen (Tylenol, etc.)

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Is it safe to take pain relievers before getting the COVID-19 vaccine?

To be extra cautious, it's best to avoid taking OTC pain relievers before you get your shot. But it's OK to take Tylenol after the COVID-19 vaccine.
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Should I take an antihistamine before the COVID-19 vaccine?

It is also not recommended to take antihistamines before getting a COVID-19 vaccine to try to prevent allergic reactions.
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