Can you have brain lesions and not have MS?

The diagnosis of MS cannot be made solely on the basis of MRI because there are other diseases that cause lesions in the CNS that look like those caused by MS. And even people without any disease — particularly the elderly — can have spots on the brain that are similar to those seen in MS.
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How do I know if my brain lesions are MS?

Diagnosing MS

More than 90% of people with MS have scar tissue that shows up on an MRI scan. A spinal tap can check for abnormalities in the fluid that bathes the brain and spinal cord. Tests to look at electrical activity of nerves can also help with diagnosis.
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What diseases can cause lesions on the brain?

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  • Brain aneurysm.
  • Brain AVM (arteriovenous malformation)
  • Brain tumor (both cancerous and noncancerous)
  • Encephalitis (brain inflammation)
  • Epilepsy.
  • Hydrocephalus.
  • Multiple sclerosis.
  • Stroke.
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Can you have MS with only brain lesions?

Multiple Sclerosis: It's in Your Head

While many symptoms of MS throughout the body can be caused by lesions in either the brain or the spinal cord, cognitive symptoms of MS — those related to your memory, language, and problem solving — are believed to be caused only by lesions in the brain.
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Do lesions always show up with MS?

MRI scans are an important way to help health care providers figure out if a person has MS or not, but MRI scans cannot diagnose MS by themselves. While it is true that almost all people with MS will have lesions on MRI, not all people with MRI lesions have MS.
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MS with No Lesions - National MS Society



Can you have a clear MRI and still have MS?

MS can be present even with a normal MRI and spinal fluid test although it's uncommon to have a completely normal MRI. Sometimes the MRI of the brain may be normal, but the MRI of the spinal cord may be abnormal and consistent with MS, so this also needs to be considered.
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How quickly do lesions appear in MS?

Most symptoms develop abruptly, within hours or days. These attacks or relapses of MS typically reach their peak within a few days at most and then resolve slowly over the next several days or weeks so that a typical relapse will be symptomatic for about eight weeks from onset to recovery. Resolution is often complete.
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Can some brain lesions be harmless?

Brain lesions are areas of abnormal tissue that have been damaged due to injury or disease, which can range from being relatively harmless to life-threatening.
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How many brain lesions do you need to be diagnosed with MS?

For the diagnosis of multiple sclerosis, there should be at least one typical multiple sclerosis lesion in at least two characteristic regions [periventricular (abutting the lateral ventricles), juxtacortical/cortical, infratentorial, spinal cord] to support dissemination in space (Thompson et al., 2018).
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What do brain lesions on MRI mean?

Brain lesions seen on MRI may indicate any number of possible conditions. Here the brain lesion depicts tissue damage from an ischemic stroke — a state of severely reduced blood flow to the brain, which deprives brain cells of vital oxygen and nutrients.
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Can a healthy person have brain lesions?

Brain lesions can happen with any condition or circumstance that can damage your brain. Medical conditions that can cause brain lesions include: Brain tumors (including cancer). Congenital disorders (conditions you have at birth) and metabolic disorders.
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Are brain lesions something to worry about?

A brain lesion may involve small to large areas of your brain, and the severity of the underlying condition may range from relatively minor to life-threatening.
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What is the most common cause of lesions in the brain?

Injury, infection or disease can damage brain tissue

An intracranial lesion or brain lesion is damage to the brain tissue because of illness, injury, disease or infection, or some other cause. The cause of a brain lesion is sometimes unknown.
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Where do MS lesions show up first?

Signs and Symptoms

Characteristic lesions are located in the periventricular and juxtacortical regions, in addition to the brainstem, cerebellum, spinal cord, and optic nerve.
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How common are brain lesions?

They are not common, but they are life threatening. Brain abscesses often occur after an infection, usually in a nearby area, such as an ear, sinus, or dental infection. They can also appear after injury or surgery to the skull. Read more about the causes of abscesses.
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Where are the most common places for MS lesions?

Lesions may be observed anywhere in the CNS white matter, including the supratentorium, infratentorium, and spinal cord; however, more typical locations for MS lesions include the periventricular white matter, brainstem, cerebellum, and spinal cord.
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Are brain lesions from MS permanent?

Can Lesions Heal Once They Appear? “Absolutely,” says Dr. Hua. “It's not specific to MS, but in any process where there's some sort of brain injury, there will always be healing, as well.
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Can stress cause brain lesions?

Psychological stress is linked to multiple sclerosis (MS) severity (e.g., to a heightened risk of brain lesion development). The exact mechanisms underlying this association are unknown.
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How do you rule out MS?

Tests to diagnose MS
  1. Neurological examination. Your neurologist will ask you lots of questions about your health problems and symptoms, now and in the past. ...
  2. Magnetic resonance imaging (MRI) ...
  3. Evoked potentials tests. ...
  4. Lumbar puncture or spinal tap. ...
  5. Blood tests and tests for other conditions.
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Can you live a long life with a brain lesion?

Some brain tumours grow very slowly (low grade) and cannot be cured. Depending on your age at diagnosis, the tumour may eventually cause your death. Or you may live a full life and die from something else. It will depend on your tumour type, where it is in the brain, and how it responds to treatment.
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What treatment is available for brain lesions?

Treatment options for people with brain metastases often include medication, surgery, stereotactic radiosurgery, whole-brain radiation therapy or some combination of these. In certain situations, your treatment team may consider drug treatments for brain metastases.
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What percentage of brain lesions are benign?

And an estimated 90,000 people will receive a primary brain tumor diagnosis in 2022. Here's a breakdown that may surprise many: About 71 percent of all brain tumors are benign and about 29 percent are malignant.
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What can mimic MS lesions?

Conditions That Can Seem Like MS
  • Epstein-Barr Virus.
  • Vitamin B12 Deficiency.
  • Diabetes.
  • Nerve Damage.
  • Eye Problems.
  • Stroke.
  • Lupus and Other Autoimmune Diseases.
  • Parkinson's Disease.
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Does early MS show up on MRI?

An MRI scan can detect MS activity early on , sometimes before an individual experiences any worsening symptoms.
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How do you confirm MS diagnosis?

Brain MRI is often used to help diagnose multiple sclerosis.
...
MRI multiple sclerosis lesions
  1. Blood tests, to help rule out other diseases with symptoms like MS . ...
  2. Spinal tap (lumbar puncture), in which a small sample of cerebrospinal fluid is removed from your spinal canal for laboratory analysis.
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