Can you feel worse when you start taking sertraline?

Even though sertraline is a preferred medication to treat depression, it might actually make you feel worse before you feel better. After you start taking sertraline — or after your dose is changed — thoughts of suicide are possible. This mostly happens in people ages 24 or younger.
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Why does sertraline make you feel worse at first?

SSRIs release two chemicals in the brain that kick in at different times, causing a period of negative effects on mental health, the authors report. The first chemical is serotonin, which is released very soon after an SSRI is taken but might not lessen depressive symptoms until after a couple of weeks.
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How long does sertraline make you feel worse for?

Taking Zoloft may make you feel uncomfortable or weird at first as your body starts to process the medication. After a week or two these side effects will go away for most people as their bodies get used to the medication.
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How does sertraline make you feel when you first start?

Sertraline can make you feel very restless in the first few weeks that you take it and may affect you when you sit or stand still. It can also disturb your sleep, and your eyesight.
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How long does it take to adjust to taking sertraline?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
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What To Avoid When Taking Sertraline, Fluoxetine, Paroxetine, Escitalopram (SSRIs)



Why do you feel worse when starting antidepressants?

When you start an antidepressant medicine, you may feel worse before you feel better. This is because the side effects often happen before your symptoms improve. Remember: Over time, many of the side effects of the medicine go down and the benefits increase.
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Does Zoloft make anxiety worse at first?

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop ...
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What are the most common side effects of sertraline?

Sertraline side effects
  • nausea, loss of appetite, diarrhea, and indigestion.
  • change in sleep habits, including increased sleepiness and insomnia.
  • increased sweating.
  • sexual problems, including decreased sex drive and ejaculation failure.
  • tremor or shaking.
  • tiredness and fatigue.
  • agitation.
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How do you deal with the side effects of sertraline?

Consider these strategies:
  1. Take your antidepressant with food, unless otherwise directed.
  2. Eat smaller, more-frequent meals.
  3. Suck on sugarless hard candy.
  4. Drink plenty of fluids, such as cool water. ...
  5. Talk to your doctor about a dosage change or a slow-release form of the medication.
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How long does it take sertraline to work for anxiety?

The initial effects may begin within the first 1 to 2 weeks of treatment. Some patients may require a longer time period. Other uses for Zoloft, such as obsessive compulsive disorder (OCD) or posttraumatic stress disorder (PTSD), may take up to 12 weeks of continuous treatment.
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When do antidepressant side effects start?

During the first few weeks' people commonly experience some side effects or feel worse before they begin to feel better. Although the newer Selective serotonin reuptake inhibitors (SSRIs) usually have fewer or less severe side effects than tricyclic antidepressants, various side effects can occur with them all.
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How do I know if I have serotonin syndrome?

Serotonin Syndrome Symptoms

Gastrointestinal symptoms include diarrhea and vomiting. Nervous system symptoms include overactive reflexes and muscle spasms, said Su. Other serotonin syndrome symptoms include high body temperature, sweating, shivering, clumsiness, tremors, and confusion and other mental changes.
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Can sertraline make you depressed?

Suicidal thoughts and behavior

Zoloft (sertraline) can raise the risk of suicidal thoughts or behavior. Watch for new or worsening depression, suicidal thoughts or behavior, especially during the first few months of treatment or when the dose changes.
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When is the best time to take sertraline?

When is the best time to take sertraline (Zoloft)? Typically, your doctor will recommend that you take your prescribed dose of sertraline once a day, either in the morning or evening. If sertraline makes you drowsy, your doctor may suggest that you take it at bedtime.
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Does anxiety get worse before it gets better?

According to most experts, people with anxiety disorders put off seeking treatment for about 10 years. Instead of being proactive in treating an anxiety disorder, they delay getting help in the hopes that things will “get better” at some point. Truth be told, anxiety generally worsens over time.
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Can antidepressants make you more anxious?

Although they're often used to treat anxiety, antidepressants can potentially cause anxiety, especially when people begin taking them for depression.
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Can sertraline make you feel shaky?

Common side effects may include: indigestion, nausea, diarrhea, loss of appetite; sweating; tremors; or.
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Can sertraline worsen anxiety?

Psychiatrists should always bear in mind the possibility of the development of jitteriness/anxiety syndrome when prescribing sertraline. It should be noted that jitteriness/anxiety syndrome may develop rapidly after the initiation of oral administration of even low-dose sertraline.
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How long does it take to adjust to a new antidepressant?

Your new antidepressant might take a while to kick in

Antidepressants can take up to 1 month to start working in full effect. Until then, your symptoms may get better, worse, or stay the same. During this time, be sure to keep track of how you're feeling.
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What to expect when taking antidepressants for the first time?

Understand what to expect. There may be mild, short-term side effects in the first few weeks. Some people say the antidepressant makes them too drowsy or unable to sleep, that they feel agitated or nauseous, or have headaches. If you're concerned about side effects, call your doctor.
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Can too much serotonin cause anxiety?

It has long been suggested that over-activity of the serotonin system may relate to mood disorders such as depression and anxiety, as these seem characterized by too much withdrawal and avoidance.
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How long does serotonin syndrome take to start?

Most cases of serotonin syndrome start within 24 hours after starting or increasing a serotonergic medication and the majority of those start within six hours.
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What are the mild symptoms of serotonin syndrome?

Mild serotonin syndrome symptoms often includes the following: Shivering and tremors. Twitching or involuntary muscle movements. Excessive sweating.
...
More severe signs of serotonin syndrome include:
  • Fever.
  • Anxiety.
  • Confusion.
  • Agitation.
  • Varying heart rate or blood pressure.
  • Delirium.
  • Muscle rigidity.
  • Restlessness.
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Can antidepressants make you feel more depressed?

Antidepressants can make you feel tired, cause concentration problems, and lead to changes in sleep and appetite. These side effects can make you feel like your depression is getting worse, instead of getting better.
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How common are side effects of antidepressants?

Thirty-eight percent of the approximately 700 patients surveyed reported having experienced a side effect as a result of taking a selective serotonin reuptake inhibitor antidepressant; the most common side effects mentioned were sexual functioning, sleepiness, and weight gain.
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