Can you crush Prascend?

PRASCEND tablets should not be crushed due to the potential for increased human exposure and care should be taken to minimize exposure when splitting tablets.

Can you dissolve Prascend in water?

As the data sheet for Prascend suggests that Prascend can be dissolved in water and/or mixed with molasses or other sweetener, as far as we are aware it should be ok to use Coca Cola to dissolve the tablet.

Can you touch Prascend?

Not for use in humans. Do not ingest the product. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Pergolide, like other ergot derivatives, may cause emesis, dizziness, lethargy or low blood pressure.

How do I get my horse to eat pergolide?

Dissolve the tablet in apple juice or water and add to a small amount of feed. Ensure the horse eats every last bit. Buy empty gelatine pill capsules (size one) online and place the tablet inside. Then just add them to a feed.

Does Prascend have to be given at the same time every day?

Does it matter what time of day I give Prascend/pergolide? A. No. There is currently no recommendation for giving Prascend/pergolide at any particular time of day - this was confirmed by Dr Marian Little in The Horse.com's Ask the Vet Live Managing Horses with PPID in February 2014 - see notes.

6 Stages of Having a Crush

Can Prascend be dissolved?

If your horse doesn't have laminitis you could add a small amount of molasses or honey to a handful of feed and put the tablet in. 7. Dissolve the tablet in water and add to the feed or syringe directly into their mouth. (NB Do NOT crush the tablets).

How long does Prascend take to work in horses?

How long until I see an improvement with my horse after beginning treatment with PRASCEND? Depending on the specific clinical sign, improvement may be observed beginning within 30 days and continue through 6 months of initial treatment.

Can you crush pergolide?

Do not ingest the product. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Pergolide, like other ergot derivatives, may cause emesis, dizziness, lethargy or low blood pressure. Pregnant or lactating women should wear gloves when administering this product.

Does Prascend stop laminitis?

Several studies report improvement in the clinical signs of laminitis during treatment with pergolide. However, such improvements cannot be attributed to pergolide rather than other interventions such as farriery, rest or analgesia.

Does pergolide need to be refrigerated?

Compounded pergolide formulations in aqueous vehicles should be stored in a dark container, protected from light, and refrigerated and should not be used >30 days after produced.

What happens if a human takes Prascend?

Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary.

Can Prascend cause colic?

Prascend® is well tolerated in horses. Potential adverse reactions in horses include inappetence, transient anorexia and lethargy, mild central nervous system signs (e.g. mild depression, mild ataxia and mild hyperexcitability), diarrhoea and colic. These signs are usually mild and transient in nature.

What hay should you feed a horse with Cushings?

Alfalfa averages 10-15% NSC, and oat hay is very high, averaging 22%. Alfalfa can be a good option for a horse with Cushings if they are a hard time holding their weight because it is more calorie-dense than grass hay.

Can a horse overdose on PRASCEND?

Pergolide overdose in horses is rare. Side effects of pergolide overdose in horses are related to dopaminergic central nervous effects. Paraffin oil and activated charcoal via a nasogastric tube might prevent systemic absorption of pergolide if overdosed.

Can Prascend cause lameness?

Increased or decreased sweating may occur. Reproductive cycles may be abnormal or absent, potentially leading to infertility. A cause of lameness in both forelimb and hindlimb of athletic horses.

What is a normal ACTH level in horses?

Samples taken during this time period may have up to 3 times reference levels of ACTH in normal horses." Their normal cut-off is 35 pg/ml (outside of the seasonal rise), therefore up to 3 times this might mean an ACTH of up to 105 pg/ml might be considered negative for PPID between August and October.

What does Prascend do for Cushings horses?

What is Prascend? Prascend is a medicine licensed to treat the clinical signs associated with Equine Cushing's disease in horses. It contains the active ingredient pergolide. Prascend works by mimicking the action of dopamine and therefore regulating the production of hormones from the pituitary gland.

Is beet pulp good for horses with Cushings?

Triple Crown Senior (http://www.triplecrownfeed.com/products/feeds/senior-horse-feed- formula-seniorhorsefeed) is a beet pulp-based, textured feed recommended for Cushing's horses that have a hard time maintaining weight and need a little extra fat, without the extra carbohydrates.

Can Cushings horses have grass?

Pasture grasses can have a high NSC content, especially during the spring and fall seasons, and the risk of colic and laminitis is greater when horses are on pasture. Since laminitis and founder are more common in horses with Cushing's disease, pasture grazing should be severely limited or totally avoided.

Can you feed oats to horses with Cushings?

Even though oats are the grain lowest in sugar and starch, at around 45 to 50% starch they are still far too high in starch for horses on a low sugar and starch diet, eg insulin resistant horses, horses prone to laminitis, those with disorders like Cushings or PSSM etc, as well as many horses who are prone to ulcers, ...

How do you give a horse a Prascend?

The product should be administered orally, once daily. To facilitate administration, the required daily dose should be placed in a small amount of water and/or mixed with molasses or other sweetener and agitated until dissolved.

How much Prascend should I give my horse?

Starting dose:

Administer orally at a starting dose of 2 mcg/kg once daily. Dosage may be adjusted to effect, not to exceed 4 mcg/kg daily. Most horses respond to therapy at an average dose of 2 mcg pergolide/kg body weight. Initial clinical improvement with pergolide is expected within 6 to 12 weeks.

What does chasteberry do for horses?

“True to its name, chasteberry is purportedly useful for making mares a little more cheerful and easier to handle, supporting hormone levels, and promoting balanced behavior,” relayed Kathleen Crandell, Ph. D., a nutritionist for Kentucky Equine Research (KER).

Why was pergolide taken off the market?

FDA today announces that manufacturers of pergolide drug products, which are used to treat Parkinson's disease, will voluntarily remove these drugs from the market because of the risk of serious damage to patients' heart valves.

Does pergolide increase dopamine?

Abstract. When used to treat patients with Parkinson's disease pergolide acts at dopamine receptors in the corpus striatum to improve locomotor activity, reducing the tremor, gait disturbances, bradykinesia or akinesia and rigidity experienced by such patients.