Can vitamin d3 increase uric acid levels?

Vitamin D supplementation lowers serum uric acid in prediabetic patients with hyperuricaemia

hyperuricaemia

Introduction. Hyperuricemia is an elevated uric acid level in the blood. The normal upper limit is 6.8mg/dL, and anything over 7 mg/dL is considered saturated, and symptoms can occur. This elevated level is the result of increased production, decreased excretion of uric acid, or a combination of both processes.

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Hyperuricemia - StatPearls - NCBI Bookshelf

, and supplementation might be considered to help alleviate hyperuricaemia in these patients.

Can vitamin D cause high uric acid levels?

Coinciding with our results, a research among postmenopausal Chinese Han women found a significant association between the vitamin D insufficiency and elevated uric acid (29). Another similar study among elderly Egyptians found that the low level of vitamin D was significantly associated with high uric acid level (30).

Does vitamin D3 cause gout?

Among people with gout who took vitamin D supplements, 40.0% reported being advised by a doctor to take the supplement. Conclusion: In this large nationally representative population-based cross-sectional study, vitamin D was not associated with gout.

Which vitamin increases uric acid?

Previous evidence ^{23 24 25 26 27} showed that VIT D deficiency might increase the risk of high serum uric acid (SUA).

What happens if vitamin D3 increases?

The main consequence of vitamin D toxicity is a buildup of calcium in your blood (hypercalcemia), which can cause nausea and vomiting, weakness, and frequent urination. Vitamin D toxicity might progress to bone pain and kidney problems, such as the formation of calcium stones.

GOUT AND VITAMIN D

What are the negative effects of vitamin D3?

What happens if you take vitamin D3 everyday?

Taking vitamin D for long periods of time in doses higher than 4000 IU (100 mcg) daily is possibly unsafe and may cause very high levels of calcium in the blood. Pregnancy and breast-feeding: Vitamin D is likely safe during pregnancy and breast-feeding when used in daily amounts below 4000 IU (100 mcg).

Does vitamin d3 reduce uric acid?

Moreover, changes in the concentrations of both serum 1,25(OH)₂D and uric acid were demonstrated during vitamin D supplementation. Taken together, these results suggest that vitamin D may reduce serum uric acid concentration.

Which vitamin reduce uric acid?

Several metabolic studies and a recent double-blinded placebo-controlled randomized trial have shown that higher vitamin C intake significantly reduces serum uric acid levels.

Is vitamin D good for gout sufferers?

Vitamin D is very important for you as a gout sufferer, actually more than you think! Vitamin D is very important for your bone health by increasing the absorption of calcium and phosphorus.

Can vitamin d3 cause inflammation?

Low levels of vitamin D have been consistently linked to an increased risk of inflammatory diseases, such as cardiovascular disease, arthritis, multiple sclerosis (MS), and sepsis.

What vitamins should I avoid with gout?

Avoid taking extra niacin and vitamin A. Both may play a role in gout.

What causes sudden rise in uric acid?

Causes of a high uric acid level in the blood include: Diuretics (water retention relievers) Drinking too much alcohol. Drinking too much soda or eating too much of foods that contain fructose, a type of sugar.

Does zinc increase uric acid?

Both folic acid and zinc significantly reduce uric acid levels and alleviate hyperuricemia. However, whether the underlying mechanisms are associated with the regulation of the gut microbiota remain unknown.

Can vitamin D3 cause kidney stones?

The largest meta-analysis by Malihi et al. concluded that vitamin D2 and D3 supplementation resulted in changes in calcium metabolism, with increased risks of hypercalcemia and hypercalciuria, but no increase in the risk of reported kidney stones [14].

What foods break down uric acid?

Does b12 lower uric acid?

Long-term supplementation with folic acid and vitamin B-12 has no effect on circulating uric acid concentrations in Norwegian patients with coronary artery disease.

Does d3 affect kidney function?

"The public should know that taking more vitamin D than is recommended does not necessarily lead to added benefit. Rather, it can lead to increased harm and specifically kidney failure," he added.

How much vitamin D3 per day is OK?

In patients with vitamin D levels less than 20 ng/mL, start with 50,000 IUs of vitamin D3 once a week for 6 to 8 weeks. After that, a dose of 800 to 2000 IU per day should be taken to maintain vitamin D levels above 30 ng/mL.

Is it better to take vitamin D3 every day or once a week?

Oral vitamin D3 can be taken once a day but also with longer intervals because of its long half life, being around 25 days. It is not known whether equivalent doses once a week or once a month are equally effective.

How much vitamin D3 is OK daily?

Unless your doctor recommends it, avoid taking more than 4,000 IU per day, which is considered the safe upper limit.

Who should not take vitamin D3 supplements?

What organs does vitamin D3 affect?

Vitamin D undergoes further chemical changes, first in the liver and then in the kidneys, to become calcitriol. Calcitriol acts on the intestine, kidneys, and bones to maintain normal levels of blood calcium and phosphorus.