Can too much biotin cause thyroid problems?

Biotin is a common component of multivitamin preparations and at high doses it has been reported to cause interference in immunoassays resulting in abnormal thyroid function tests

thyroid function tests

A Thyroid function test (TFT) commonly refers to the quantitation of thyroid stimulating hormone (TSH) and circulating thyroid hormones in serum to assess the ability of the thyroid gland to produce and regulate thyroid hormone production.

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Does biotin cause thyroid issues?

Most commonly, biotin use can result in falsely high levels of T₄ and T₃ and falsely low levels of TSH, leading to either a wrong diagnosis of hyperthyroidism or that the thyroid hormone dose is too high.

Is 10000 mcg biotin too much?

Mayo Clinic states that 10,000 mcg is a safe dose, as no adverse side effects have been noted to date. Reassuringly, even “mega doses” of 300,000 mcg found no side effects in neurological research.

What supplements can affect thyroid test results?

Biotin supplements, for example, can interfere with thyroid function tests by showing falsely low TSH levels. The ATA recommends you stop taking biotin for at least two days before a thyroid test to avoid misleading results.

What vitamins affect thyroid levels?

How Biotin Interferes with Thyroid Lab Tests

How long should you stop biotin before thyroid test?

The biotin should be discontinued for at least 48-72 hours before thyroid assaying by any commonly used biotin-streptavidin immunoassay.

Can you get too much biotin?

Biotin supplements can cause problems if you take too much. Side effects can include skin rashes, digestive upset, problems with insulin release, and kidney problems. As with any supplement, the safety of long-term or high-dose use isn't known.

Does biotin skew thyroid tests?

Often, people don't realize that Biotin, a B vitamin, can skew the results of thyroid blood tests, resulting in a possible misdiagnosis. Studies have shown Biotin, even in low doses, can interfere with diagnostic blood tests leading to both false negatives and false positives.

Can you take biotin with thyroid medication?

Biotin doesn't interfere with your thyroid medication, but it does interfere with your thyroid blood test and can mess up your numbers. Stop taking biotin at least 2 days before having a TSH blood test done.

What does biotin interfere with?

Excess biotin in the blood from supplements can block that binding and the substance won't be measured accurately. Most of the published research on biotin interference covers hormone tests, such as parathyroid hormone (PTH), thyroid stimulating hormone (TSH), T4 and T3 tests, as well as tests for troponin.

Can I take 5000 mcg of biotin a day?

Biotin is generally safe even at high dosages. Side effects of biotin are minimal and easily reversed because excess biotin is easily passed by the body through urine. We recommend taking 500 mcg-5,000 mcg of biotin per day to support healthy hair, skin, and nails.

How much is too much biotin a day?

No toxicity of excess biotin intake has been described. “It is a B vitamin, so it is difficult to overdose on it—most people will urinate out what they do not need,” says Johnson. “With that said, I suggest not taking more than the daily recommended dose of 30-100 mcg per day for an adult.”

How much biotin should I take daily for hair loss?

The Takeaway

If you're experiencing hair loss or hair thinning, biotin supplements could help. Research suggests that increasing your biotin intake between 2mg and 5mg per day could improve the strength and thickness of your hair.

Does biotin help with thyroid hair loss?

Treat nutritional deficiencies. Nutritional deficiencies can contribute to hair loss even without a thyroid condition. Specifically, researchers explain that levels of the following may play a role in hair retention and hair loss: vitamins B-7 (biotin) and B complex.

Can vitamins cause thyroid problems?

For example, many thyroid supplements contain high amounts of iodine and may contain thyroid hormones. Taking these supplements can lead to dangerous side effects and create thyroid issues in people with healthy thyroid function ( 11 ).

Will 30 mcg of biotin affect thyroid tests?

Many patients are taking megadoses of biotin that can cause falsely high and falsely low results in a variety of laboratory tests, including thyroid tests. Patients are taking these supplements mainly to improve their hair, skin, and nails — and might not consider them medications to report on their list.

How much does biotin affect thyroid?

Biotin is a common component of multivitamin preparations and at high doses it has been reported to cause interference in immunoassays resulting in abnormal thyroid function tests [2].

Can too much vitamin D affect thyroid?

Importantly, both vitamin D and thyroid hormone bind to similar receptors called steroid hormone receptors. A different gene in the Vitamin D receptor was shown to predispose people to autoimmune thyroid disease including Graves' disease and Hashimoto's thyroiditis.

Does biotin affect iron levels?

Biotin in supplements can also affect tests for heart failure, pregnancy, cancer, and iron-deficiency anemia. Experts say the problem is not new. “In the lab community, people have known about this for a long time,” said Danni Li, PhD, director of clinical chemistry at the University of Minnesota Medical Center.

How long does it take to get biotin out of your system?

Your doctor also can advise you on whether you should stop taking your supplement ahead of an upcoming lab test. Most water-soluble vitamins flush out of your body in 24 to 48 hours, but it might take longer depending on the dose you're taking.

What are the symptoms of a overactive thyroid?

How much biotin should you take for hair growth?

Recommended dosage

The Food and Drug Administration (FDA) does not have a daily recommended dietary allowance for biotin. However, according to estimates, an intake of 30 micrograms (mcg) may be adequate. The average intake of biotin in Western countries, excluding the United States, is an estimated 35–70 mcg per day.

What are the symptoms of biotin overdose?

Excess in the body is rare, and since biotin is a water-soluble vitamin, it is excreted in the urine when in excess. Signs and symptoms of biotin overdose may include and are not limited to insomnia, excessive thirst, and urination.

Is 20000 mcg biotin too much?

Can You Take Too Much Biotin? Several studies have found no adverse effects of 10,000–50,000 mcg/day biotin. Doses up to 200,000 mcg/day oral biotin or 20,000 mcg/day are administered intravenously in patients with biotinidase deficiency without symptoms of toxicity.

What is the best multivitamin for hypothyroidism?