Can mono mimic leukemia?

Occasionally, this condition advances into infectious mononucleosis and can resemble or cause acute leukemia, lymphoma, and many other hematologic emergencies.

Can mono be misdiagnosed as leukemia?

The disease is usually self limiting in most cases. EBV is also the most common infectious trigger of hemophagocytic lymphohistiocytosis [2, 3]. The presentation of both diseases mimics lymphoreticular malignancies and frequently it can be mistaken for leukemia and lymphomas.

Can mono lead to leukemia?

The association of infectious mononucleosis and an immunocompromised host such as occurs in acute leukemia is reported. The most common cause of infectious mononucleosis is Epstein-Barr virus (EBV) and cytomegalovirus (CMV).

Can mono be confused with cancer?

Oct. 1, 2003 -- New research confirms a long-suspected link between infectious mononucleosis -- also known as the "kissing disease" -- and a cancer commonly found in young adults. Researchers are implicating the Epstein-Barr virus (EBV), the cause of mononucleosis, in roughly one-third of Hodgkin's disease cases.

Can mono be mistaken for something else?

Mononucleosis is frequently mistaken for other illnesses, such as strep throat, chronic fatigue, or another infection, because the symptoms can overlap, Ramilo says.

What is MONO? Symptoms, Diagnosis

What diseases can be mistaken for mono?

Can lymphoma cause a false-positive mono test?

In rare cases, the test is positive even though you do not have mono. This is called a false-positive result, and it may occur in people with: Hepatitis. Leukemia or lymphoma.

Can mono be mistaken for lymphoma?

The morphological features of EBV-infected lymphoid tissue can easily mimic lymphoma. Furthermore, the immunophenotype of the immunoblasts has not been well characterized.

Can mono look like lymphoma?

Unfortunately, these biopsies can lead to a misdiagnosis of lymphoma, as involvement of lymphoid tissue by acute EBV infection can resemble both Hodgkin lymphoma and non-Hodgkin lymphoma. This relatively common pitfall can result in inappropriate treatment.

Can Epstein Barr mimic lymphoma?

EBV mimicking lymphoma. Acute EBV infection may present in different ways and can mimic malignant lymphoma at presentation. Negative EBV serology can be misleading.

Can glandular fever cause leukemia?

If people pick up EBV when they are older, they can get glandular fever (sometimes called 'mono' or 'kissing disease'). Glandular fever can be very unpleasant, but it usually passes within a few weeks. Glandular fever itself doesn't cause cancer.

Can mono cause leukopenia?

Discussion: During the last 10 years only several cases of severe leukopenia with acute infectious mononucleosis had been reported in literature. In all cases it was associated with some other hematological complications and it occurred in young adults without previously registered immunodeficiency.

Can Lyme mimic leukemia?

There is some evidence that inflammation due to Lyme disease can sometimes cause certain forms of blood cancer, such as lymphoma. But most people with Lyme disease do not develop leukemia. Some people with leukemia develop a rash due to burst blood vessels.

What were your first signs of leukemia?

Does leukemia always show up in blood work?

Blood tests.

By looking at a sample of your blood, your doctor can determine if you have abnormal levels of red or white blood cells or platelets — which may suggest leukemia. A blood test may also show the presence of leukemia cells, though not all types of leukemia cause the leukemia cells to circulate in the blood.

Can leukemia be missed on blood test?

If your first alert to leukemia comes from routine blood testing, you're not alone. This happens because early symptoms of leukemia can be vague and easy to miss.

What can be misdiagnosed as lymphoma?

Reactive lesions such as Kikuchi lymphadenitis, infectious mononucleosis, autoimmune lymphoproliferative syndrome, and immunoglobulin G4-related sclerosing disease can be misdiagnosed as lymphomas.

What can be mistaken for lymphoma?

Would lymphoma show up on a CBC?

Complete blood count (CBC)

White blood cells, which fight infection. A low white blood cell count can occur due to lymphoma or other conditions, like an autoimmune disorder. Lymphoma sometimes shows in the blood as an abnormally high white blood cell count.

What were your first signs of lymphoma?

What is the most common early symptom of lymphoma?

The most common sign of lymphoma is a lump or lumps, usually in the neck, armpit or groin. These lumps are swollen lymph nodes, sometimes known as 'glands'. Usually, they're painless. Fatigue is different to normal tiredness.

Is there a link between glandular fever and lymphoma?

People who have had glandular fever have an increased risk of Hodgkin lymphoma. It's estimated that around 40 out of 100 cases (40%) of Hodgkin lymphoma in the UK are related to EBV infection. But it's important to remember that most people who have glandular fever will not develop cancer as a result.

What can cause false-positive mono?

What mimics EBV?

Epstein-Barr virus is the cause of classic infectious mononucleosis. Other infections may mimic Epstein-Barr virus infectious mononucleosis, for example, cytomegalovirus, human herpes virus-6, toxoplasmosis, lymphoma, cat scratch fever, and rubella.

What can cause false-positive EBV?

The false positives could be the result of EBV reactivation due to cross-reactions with IgM of other viruses or to the reappearance of EBV IgM due to polyclonal activation induced by cytomegalovirus, adenovirus, hepatitis A virus, Toxoplasma gondii, rubella virus, or other as yet unknown agents that produce an ...