Can metronidazole cause damage?

It can give you severe side effects such as feeling or being sick, stomach pain, hot flushes, difficulty breathing, a pounding heartbeat (palpitations) and headaches.

Can metronidazole cause permanent damage?

Serious side effects of Flagyl and Flagyl ER include brain disease, fevers, mouth sores, painful urination, nerve damage resulting in prickling or tingling sensations that may become permanent, cystitis, pelvic pain or pressure, decreased sex drive, inflammation of the lining of the rectum, inflammation of the mouth ...

What does metronidazole do to the body?

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis). Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth.

How long can you safely take metronidazole?

Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days.

Is metronidazole hard on your body?

It can give you severe side effects such as feeling or being sick, stomach pain, hot flushes, difficulty breathing, a pounding heartbeat (palpitations) and headaches.

Metronidazole - How it acts? | Mechanism, side effects and uses

Can metronidazole damage your liver?

The liver injury from metronidazole is rare, but can result in liver failure and death. In typical cases, recovery is expected in 1 to 3 months. Rechallenge results in prompt recurrence and should be avoided.

What happens if you take metronidazole for too long?

Patients should be monitored for adverse effects such as peripheral or central neuropathy (such as paraesthesia, ataxia, dizziness, convulsive seizures), particularly if metronidazole has been prescribed for long-term use.

Who should not take metronidazole?

You should not use this medicine if you are allergic to metronidazole, secnidazole, or tinidazole, or if: you drank alcohol in the past 3 days; you consumed foods or medicines that contain propylene glycol in the past 3 days; or. you took disulfiram (Antabuse) within the past 14 days.

Can you just stop taking metronidazole?

Carry on taking metronidazole tablets, liquid or suppositories until you have finished the course, even if you feel better. If you stop your treatment early, the infection could come back.

Can metronidazole weaken immune system?

Birth control: Ingredients in metronidazole vaginal cream may cause condoms and diaphragms to become less effective. Alternative forms of birth control should be considered while using this medication. Blood cell counts: This medication may cause low white blood cell counts, which can mean your immune system is weak.

What comes out after using metronidazole?

Does metronidazole vaginal gel cause white clumpy discharge? Depending on the brand, vaginal discharge can be a possible side effect of metronidazole vaginal gel. It should go away soon after completing a full course of treatment. If it doesn't, let your provider know.

Is metronidazole worth taking?

Metronidazole is a very safe and effective antibiotic medication used to treat bacterial vaginosis (BV). Many users will not experience any negative Metronidazole side effects at all and will have a very positive experience with the medication on the whole.

Is metronidazole cancerous?

MTZ is potentially carcinogenic to humans due to the following facts: it is a proven mutagen in bacterial systems, it is genotoxic to human cells and also, it is carcinogenic to animals.

Is metronidazole neuropathy reversible?

Peripheral neuropathy is the most common adverse neurologic effect caused by metronidazole. Most of the adverse effects are reversible within weeks of discontinuation of treatment.

How common is metronidazole toxicity?

Neurological toxicity is fairly common with this drug, however majority of these are peripheral neuropathy with very few cases of central nervous toxicity reported.

What should you not do while taking metronidazole?

You should not drink alcoholic beverages or take other alcohol-containing preparations while you are using this medicine and for at least 3 days after stopping it. If you have trichomoniasis: Using this medicine while you are pregnant (especially during the first 3 months of pregnancy) can harm your unborn baby.

Does metronidazole affect gut bacteria?

Metronidazole has a substantial impact on the gut microbiome. However, the recovery of the microbiome after discontinuation of administration, and the metabolic consequences of such alterations have not been investigated to date.

Is oral metronidazole safe?

This medicine may increase your risk of having serious liver problems, which may be life-threatening. This is more likely if you have Cockayne syndrome (rare form of dwarfism).

Can metronidazole affect your brain?

There have been several reported cases in which abnormalities of the brain on MRI were associated with metronidazole treatment: lesions involving the subcortical white matter, splenium, midbrain, and cerebellar dentate nuclei.

Does metronidazole have neurological side effects?

Though it is well tolerated in common setting, patient may experience serious neurologic side effects in both long term and short term use. This includes peripheral neuropathy, cerebellar dysfunction, visual impairment, vestibulotoxicity, cochleotoxicity, ataxic gait, dysarthria, seizures and encephalopathy [1–6].

Can metronidazole cause heart problems?

In cases of severe overdoses, it can cause some cardiac arrhythmias among other life-threatening complications. A common culprit of these cardiac complications is the co-ingestion of metronidazole with another medication that can cause these complications when present in excess.

What bacteria does metronidazole get rid of?

Metronidazole is highly active against gram-negative anaerobic bacteria, such as B. fragilis, and gram-positive anaerobic bacteria, such as C. difficile. The pharmacokinetic and pharmacodynamic properties of the drug are favorable, and it is available as oral, intravenous, vaginal, and topical formulations.

Does metronidazole always cure BV?

BV is treated with antibiotics, of which oral and vaginal formulations of metronidazole or clindamycin are most commonly used. Although short-term BV cure rates of multiday oral and vaginal metronidazole regimens are 65%–90%,^{11, 12} recurrence rates are high.

Should I stop taking metronidazole if I have side effects?

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. Metronidazole may cause dry mouth, an unpleasant or sharp metallic taste, and a change in taste sensation.