Can HPV return after LEEP?

Conclusions. LEEP does not completely eradicate HPV infection. HPV persistence rate after LEEP is higher in infections with type 16 and in women older than 36.5 years.
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Can precancerous cells come back after LEEP?

LEEP works very well to treat abnormal cell changes on the cervix. If all of the abnormal tissue is removed, you won't need more surgery. In some studies, doctors were able to remove all the abnormal cells in almost every case. But abnormal cells may come back in the future.
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Do I still have HPV after a LEEP?

If necessary, cervical biopsy under colposcopy was performed. Results: LEEP can effectively eliminate HPV infection. Most patients cleared HPV infection within six months. The persistent HPV infection rates were 44.6%,10.6%, 5.7%, and 2.1% after three, six, nine, and 12 months, respectively.
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Can CIN come back after LEEP?

Definitely. A few women we spoke interviewed did have a recurrence of abnormal cells after treatment for CIN3, and this was often found at a follow-up appointment. Most were treated again by LLETZ.
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Can HPV come back after its cleared?

While HPV doesn't come back after clearing completely, it's difficult to know if an infection has actually been resolved or is simply dormant. Additionally, while you're unlikely to be reinfected with the exact same type of HPV, you can be infected with another strain.
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Danielle Was Diagnosed With HPV and Shares Her Story in Preventing Cervical Cancer



What causes HPV to reactivate?

What is the cause of reactivation? Among immunosuppressed individuals, oncogenic HPV present for many years at very low levels may be responsible for the high rate of HPV-related disease. The high rate of disease among these individuals may result from reactivation of low-level persistent HPV as immunity wanes [13].
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Why does my HPV keep coming back?

The most common reason for cell changes to come back would be your immune system not getting rid of high-risk HPV. We don't yet know why some people can clear HPV and others can't.
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How common is a second LEEP procedure?

3.2% (7 patients) were diagnosed with HSIL and underwent a second LEEP. This study found that 14.0% of patients (n = 31) required further follow up based on findings at the second colposcopy follow up visit.
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Can you get HPV 16 twice?

In theory, once you have been infected with HPV you should be immune to that type and should not be reinfected. However, studies have shown that natural immunity to HPV is poor and you can be reinfected with the same virus type.
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Will I always test positive for HPV?

People often never know they have caught it or passed it on. “HPV could've been there for years before it shows up, if it ever does,” says Ramondetta. When talking to your partner about your diagnosis, remember 80% of people will have HPV at some point in their life.
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How do I get rid of persistent HPV 16?

If your doctor decides to treat the abnormal cells, they may use one of these methods:
  1. Cryotherapy. This involves freezing the abnormal cells with liquid nitrogen or carbon dioxide.
  2. Conization. This procedure removes the abnormal areas.
  3. Laser therapy. ...
  4. Loop electrosurgical excision procedure (LEEP).
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Does high risk HPV go away?

High-risk HPV types

Infection with HPV is very common. In most people, the body is able to clear the infection on its own. But sometimes, the infection doesn't go away. Chronic, or long-lasting infection, especially when it's caused by certain high-risk HPV types, can cause cancer over time.
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How many times can you get a LEEP?

If the margins are positive, you may need a repeat procedure. In addition, six months following a LEEP, you'll have a follow-up appointment that includes Pap and HPV tests. In some cases, abnormal cells are found again. If this happens, you may require another LEEP.
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How do you get rid of chronic HPV?

Treatment
  1. Salicylic acid. Over-the-counter treatments that contain salicylic acid work by removing layers of a wart a little at a time. ...
  2. Imiquimod. This prescription cream might enhance your immune system's ability to fight HPV . ...
  3. Podofilox. ...
  4. Trichloroacetic acid.
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What is considered persistent HPV?

Most studies of HPV persistence have defined persistence as the detection of the same HPV type at 2–3 consecutive visits, each 2–24 months apart [10–18].
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Can you have 2 strains of HPV?

Of the more than 150 strains of HPV, 40 affect the genital area, but most don't pose a serious risk to health. A person can be infected with more than one HPV strain at a time.
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How have I got HPV in a long term relationship?

You can get HPV by having vaginal, anal, or oral sex with someone who has the virus. It is most commonly spread during vaginal or anal sex. It also spreads through close skin-to-skin touching during sex. A person with HPV can pass the infection to someone even when they have no signs or symptoms.
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What happens if you test positive for HPV twice?

Testing positive for HPV more than once

If you test positive for high-risk HPV but you don't have cell changes on your cervix, you'll be asked to come back for a cervical screening in one year. If you test positive for HPV three times in a row you'll be invited to a colposcopy.
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Can LEEP be repeated?

In conclusion, repeat LEEP could be safely performed 4-12 weeks after the first procedure without any impact on pathological specimen examination.
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Why do I need a second LEEP procedure?

In some instances, you may need a repeat procedure to remove all the cells completely. You may also need an additional LEEP if abnormal cells return. You're at a greater risk of recurrence if you're infected with a high-risk strain of the human papillomavirus, or HPV.
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Is LEEP curative?

The standard procedure for conservative management of high-grade CIN is large loop excision of the transformation zone (LEEP) or conization. Although this treatment is generally sufficient, resulting in a complete cure, Arbyn et al [9] reported an average of 10 % residual or recurrent disease in the treated cases.
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What happens if HPV doesn't go away?

Most people clear the virus on their own in one to two years with little or no symptoms. But in some people the infection persists. The longer HPV persists the more likely it is to lead to cancer, including cancers of the cervix, penis, anus, mouth and throat.
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What is the next step after a LEEP procedure?

The most common next step after a LEEP procedure is to get a pap smear in six months. It is Really Important to get a follow-up pap smear, after the LEEP procedure.
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Can my partner reinfect me with HPV?

7. Can partners reinfect each other? Reinfection with the same type of HPV is unlikely. Partners are likely to share the same HPV type.
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