Can HPV cervical cancer come back?

Most of the time, cervical cell changes (abnormal cells) don't come back after treatment. However, sometimes they do and may need further treatment. These cell changes are also called persistent or recurrent cell changes.
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What are the odds of cervical cancer returning?

The recurrence rates of cervical cancer are 11% to 22% and 28% to 64% for those with Federation of Gynecology and Obstetrics (FIGO) stage IB-IIA and IIB-IVA disease, respectively (2). Some studies have reported that the recurrence rate for those with stage III to IVB is as high as 70% (3, 4).
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Does cervical cancer usually come back?

Approximately a third of women treated for cervical cancer will have recurrence during follow-up (11), with most relapses occurring in the first two to three years after treatment (7, 12).
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Can cervical HPV come back?

This means you should not get it again. However, studies have shown that natural immunity to HPV is poor and you can be reinfected with the same HPV type. In some cases, some people will not get the same type of HPV again, but in some cases other people will get the same type of HPV again.
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How do I know if my cervical cancer has come back?

Discharge from your vagina. Pelvic pain – pain in your lower abdomen (tummy) Leg swelling – lymphoedema can also cause leg swelling, but it is important to get any new swelling checked out. Bowel/bladder changes – particularly bleeding.
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Cervical Cancer, HPV, and Pap Test, Animation



How fast can cervical cancer recur?

Approximately 80% of recurrences will manifest within 2 years of initial diagnosis, therefore it is important that women who have been diagnosed and treated for cervical cancer undergo regular surveillance with physical and pelvic exam and Pap smear for at least five years after diagnosis.
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What are the signs of cancer coming back?

Warning signs of a distant recurrence tend to involve a different body part from the original cancer site. For example, if cancer recurs in the lungs, you might experience coughing and difficulty breathing, while a recurrence of cancer in the brain can cause seizures and headaches.
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Can HPV come back once cleared?

There's no guarantee that genital warts won't grow back again because HPV changes the cells of your body in a way that makes them likely to grow. If you have high-risk HPV that sticks around or goes dormant and keeps coming back, that's when it becomes cancer causing (or what doctors call oncogenic).
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Why has my HPV come back?

The most common reason for cell changes to come back would be your immune system not getting rid of high-risk HPV. We don't yet know why some people can clear HPV and others can't.
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Can HPV come back after hysterectomy?

It is important to counsel these patients that surgery is not a treatment for high-risk HPV infection, which is the underlying etiology of their disease. With that etiology, HPV infection is likely to persist after hysterectomy and they may develop vaginal or vulvar dysplasia.
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Can cervical cancer come back after a hysterectomy?

Patients who've had a minimally invasive radical hysterectomy for cervical cancer treatment have an 8% chance of the cancer coming back. In other words, one out of 10 patients will have a recurrence.
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Can cervical cancer be cured completely?

Cervical cancer is curable, but it is difficult for doctors to know for sure that it will never come back following treatment. Therefore, doctors often use the term “remission” to describe cancer that has gone away and is no longer causing symptoms.
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Can cervical cancer come back after LEEP?

A LEEP procedure is exceptionally effective at removing any abnormal or precancerous cells from your cervix. However, depending upon your individual situation, it is possible that abnormal cells will return again, which is why we want to have follow-up appointments and regular cervical cancer screenings with you.
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Can you get HPV cancer twice?

Most recurrences occur within the first 2 years after treatment, but some patients remain at risk of recurrence for as long as 5 years, or even longer in rare cases. Salvage therapy for recurrent HPV-positive OPSCC leads to better outcomes as compared with salvage therapy for recurrent HPV-negative disease.
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Can you live a long life after cervical cancer?

Survival for all stages of cervical cancer

more than 60 out of every 100 (more than 60%) will survive their cancer for 5 years or more after diagnosis. more than 50 women out of every 100 (more than 50%) will survive their cancer for 10 years or more after diagnosis.
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Will I always test positive for HPV?

People often never know they have caught it or passed it on. “HPV could've been there for years before it shows up, if it ever does,” says Ramondetta. When talking to your partner about your diagnosis, remember 80% of people will have HPV at some point in their life.
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What happens if you test positive for HPV twice?

Testing positive for HPV more than once

If you test positive for high-risk HPV but you don't have cell changes on your cervix, you'll be asked to come back for a cervical screening in one year. If you test positive for HPV three times in a row you'll be invited to a colposcopy.
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How many times can LEEP be performed?

If the margins are positive, you may need a repeat procedure. In addition, six months following a LEEP, you'll have a follow-up appointment that includes Pap and HPV tests. In some cases, abnormal cells are found again. If this happens, you may require another LEEP.
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Will I have HPV forever?

Most HPV infections in young men and women are transient, lasting no more than one or two years. Usually, the body clears the infection on its own. It is estimated that the infection will persist in only about 1% of women. It is those infections that persist which may lead to cancer.
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Why hasn't my body cleared HPV?

Around 90% of HPV infections clear within 2 years. For a small number of women and people with a cervix, their immune system will not be able to get rid of HPV. This is called a persistent infection. A persistent HPV infection causes the cells of the cervix to change.
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Can you get reinfected with the same strain of HPV?

For most people who become infected with genital HPV, the infection will clear on its own. Once a person has been exposed to a specific type of HPV, they cannot be reinfected with the same type again, but can be infected with other types of the virus.
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Can stress cause cancer to come back?

Study Suggests a Link between Stress and Cancer Coming Back. Stress hormones can alter the behavior of some neutrophils, potentially causing dormant cancer cells to reawaken, a study suggests. For many cancer survivors, their worst nightmare is finding out that their cancer has come back.
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Are cancers more aggressive when returning?

Cancer recurrence may seem even more unfair then. Worse, it's often more aggressive in the younger cancer survivor – it may grow and spread faster. This aggressiveness means that it could come back earlier and be harder to treat.
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What percentage of cancer survivors get cancer again?

One to three percent of survivors develop a second cancer different from the originally treated cancer. The level of risk is small, and greater numbers of survivors are living longer due to improvements in treatment. However, even thinking about the possibility of having a second cancer can be stressful.
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