Can CIN 2 come back after LEEP?

About 23% of patients develop CIN2+ after LEEP treatment due to residual or recurrent lesions. The majority of patients with HPV infection were HPV negative before treatment, but 16,4% were still HPV 16 positive after treatment, indicating that conization do not necessarily clear HPV infection rapidly.

Can abnormal cells come back after LEEP?

LEEP works very well to treat abnormal cell changes on the cervix. If all of the abnormal tissue is removed, you won't need more surgery. In some studies, doctors were able to remove all the abnormal cells in almost every case. But abnormal cells may come back in the future.

Can CIN 2 come back?

Women treated for CIN2 or CIN3 retain an elevated risk of recurrence or even invasive cancer for years following treatment (2, 3). Thus, heightened surveillance has been the rule, with uncertainty as to whether (and when) a return to normal screening intervals can be safely permitted.

How often does CIN 2 come back?

The reason for conization was CIN2 in 32.7% of patients and CIN3 in 66.9% of patients. Overall, 175 women received a second conization within the first 5 years after primary treatment, for a recurrence rate of 6%.

Can you still get cervical cancer after LEEP procedure?

LEEP does not completely eradicate HPV infection. HPV persistence rate after LEEP is higher in infections with type 16 and in women older than 36.5 years.

How I Healed Myself Naturally: Cervical Dysplasia CIN 3 (High Grade)

How often does CIN 2 become cancer?

The median time from CIN2/3 to cancer was estimated to be 23.5 years (95% confidence interval: 20.8, 26.6), and 1.6% of the lesions progressed to cancer within 10 years.

Why do I need a second LEEP procedure?

In some instances, you may need a repeat procedure to remove all the cells completely. You may also need an additional LEEP if abnormal cells return. You're at a greater risk of recurrence if you're infected with a high-risk strain of the human papillomavirus, or HPV.

How long does it take for CIN 2 to regress?

Conclusion: CIN2 lesions regress without treatment in one year, although an ablative procedure is more effective.

Should I be worried about CIN 2?

CIN 2 means two-thirds of the thickness of the cervical surface layer is affected by abnormal cells. There is a higher risk the abnormal cells will develop into cervical cancer. You may be offered treatment to stop this happening, or another colposcopy.

Can you have LEEP twice?

If the margins are positive, you may need a repeat procedure. In addition, six months following a LEEP, you'll have a follow-up appointment that includes Pap and HPV tests. In some cases, abnormal cells are found again. If this happens, you may require another LEEP.

Is CIN 2 precancerous?

CIN – The outer surface of the cervix is composed of cells called squamous cells. A precancerous lesion affecting these cells is called CIN. These changes are categorized as being mild (CIN 1) or moderate to severe (CIN 2 or 3).

Why does HPV keep coming back?

There's no guarantee that genital warts won't grow back again because HPV changes the cells of your body in a way that makes them likely to grow. If you have high-risk HPV that sticks around or goes dormant and keeps coming back, that's when it becomes cancer causing (or what doctors call oncogenic).

Can HPV come back once it has cleared?

While HPV doesn't come back after clearing completely, it's difficult to know if an infection has actually been resolved or is simply dormant. Additionally, while you're unlikely to be reinfected with the exact same type of HPV, you can be infected with another strain.

What is next after a LEEP procedure?

After LEEP, you may rest for a few minutes after the procedure before going home. You may want to wear a sanitary pad for bleeding. It is normal to have some mild cramping, spotting, and dark or black-colored discharge for several days. The dark discharge is from the medicine applied to your cervix to control bleeding.

Can you get the same strain of HPV twice?

For most people who become infected with genital HPV, the infection will clear on its own. Once a person has been exposed to a specific type of HPV, they cannot be reinfected with the same type again, but can be infected with other types of the virus.

Can HPV come back after LEEP?

Results. In our study, the rate of persistent infection from HPV 16, after LEEP, was 15.9% (29/182) with 94% (17/18) of the recurring disease occurring within 18 months of follow up.

Does CIN 2 mean I have HPV?

CIN 2 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated.

What type of HPV causes CIN 2?

Results: HPV was detected in 92.9% of women with CIN 2-3 and high-risk HPV (HR-HPV) was detected in 85.8% of them. In women with cervical cancer, HPV was positive in 96.5%, HR-HPV detected in 93%.

Does CIN 2 always need treatment?

Right now, CIN2 is typically treated. But some studies have suggested that CIN2 lesions often regress completely without treatment and should therefore be simply monitored instead.

Can HPV CIN 2 Go Away?

CIN 2 lesions often clear up on their own, but can also progress to CIN 3 lesions. CIN 3 is the most severe. It's a very slow-growing disease, though: fewer than half of CIN 3 lesions will have become cancer within 30 years.

How long does it take for CIN 2 to go away?

In a meta-analysis of 36 studies (both randomized trials and observational studies) including 3160 patients with CIN 2, at 24 months, lesions regressed in 50 percent of patients, persisted in 32 percent, and progressed to CIN 3+ in 18 percent [14].

What happens if CIN 2 is left untreated?

High-Grade Abnormalities CIN-2 & CIN-3

These cells are more likely to become cancerous and invade deeper layers of the cervix if left untreated. If high-grade abnormalities are detected on a Pap smear, the woman is advised to have a colposcopy and biopsy.

How often is LEEP successful?

Loop electrosurgical excision procedure (LEEP) is a common treatment for cervical intraepithelial neoplasia (CIN), with success rates of 60 to 95 percent reported.

What happens if LEEP doesnt work?

If LEEP doesn't remove all of the abnormal cells, you may have to have LEEP again, or your doctor or nurse may recommend more tests or a different treatment.

Can cervical dysplasia come back?

Once treated, cervical dysplasia can return. People who have severe cervical dysplasia, high-risk HPV, or whose condition goes untreated could develop cervical cancer.