Can cetirizine cause depression?

The over-the-counter allergy medication cetirizine (Zyrtec and generic) has been linked to depression, as has another type of drug, montelukast (Singulair), which is often used to treat people with allergic asthma.

Does cetirizine cause anxiety and depression?

Results: Outpatients who received cetirizine and hydroxyzine treatments reported higher scores on the depression, anxiety, and fatigue sub-scales than those who received desloratadine, levocetirizine, and rupatadine.

Does cetirizine affect mood?

Can antihistamines cause depression? One study of 92 people with chronic itchiness saw that patients who took the antihistamines cetirizine and hydroxyzine reported an increase in depression and anxiety. The effects of all antihistamines on mood disorders have yet to be studied.

Is cetirizine a depressant?

Short-Term Effects

Cetirizine may cause central nervous system depression; avoid activities requiring mental alertness until accustomed to the medication.

Can cetirizine give you anxiety?

One study also suggests cetirizine and hydroxyzine have a greater chance of causing anxiety and mood changes than other antihistamines. Hydroxyzine can also be used to treat anxiety conditions. So if you notice your symptoms worsen after starting this medication, contact your provider to discuss it further.

Medications that can Cause Depression 2022

Can antihistamines cause mood swings?

In addition, changes in a person's mood and energy level could also be due to side effects from common allergy medications, such as antihistamines.

Why do antihistamines give me anxiety?

In some people, taking Benadryl can actually have a stimulant effect, which is called paradoxical excitation. People that experience this after taking Benadryl may report feeling: excitable. nervous.

Is it OK to take cetirizine everyday?

Is cetirizine (Zyrtec) safe to take every day? Cetirizine (Zyrtec) is safe to take every day if you have allergy symptoms on a daily basis. If you don't have allergy symptoms every day, you can take it as needed on days when these symptoms bother you.

What is the side effects of cetirizine?

Cetirizine is classed as a non-drowsy antihistamine, but some people still find it makes them feel quite sleepy. Common side effects include headaches, dry mouth, feeling sick, dizziness and diarrhoea. Some brands of cetirizine come as capsules. These may contain soya oil.

Which antihistamine is best for anxiety?

Hydroxyzine's unique effect on serotonin is likely why it's the only antihistamine used for anxiety. While hydroxyzine can be used to treat many different types of anxiety disorders, it is used most often for generalized anxiety disorder (GAD), especially when it is associated with insomnia.

Can allergies cause anxiety and depression?

Many people live with seasonal and year-long allergies. When you're unable to control their symptoms, allergies can lead to anxiety or depression.

Does histamine cause anxiety?

Histamine also promotes the release of adrenalin and noradrenalin from the adrenal glands. An increase in these hormones cause many of the physical symptoms of anxiety including heart palpitations, shortness of breath, sweating, shaking and nausea.

How long does it take for cetirizine to get out of your system?

Official answer. The elimination half-life of Zyrtec is between 8 to 9 hours. It takes approximately 5.5 x elimination half-life for a medicine to be cleared from your system. For Zyrtec this is 5.5 x 9 hours which is about 2 days.

Can allergy pills cause depression?

The over-the-counter allergy medication cetirizine (Zyrtec and generic) has been linked to depression, as has another type of drug, montelukast (Singulair), which is often used to treat people with allergic asthma.

Which medications can cause depression?

Can seasonal allergies cause depression?

Large-scale population studies suggest that allergy sufferers are roughly twice as likely to have depression as people without allergies. In one such study, adults with allergic rhinitis (hay fever) were twice as likely to have been diagnosed with major depression in the previous 12 months.

Is cetirizine good for sleep?

Second-generation antihistamines are less likely to cause drowsiness. People use them to treat long-term allergy symptoms, and they are not effective as sleeping aids. The following are nonsedating antihistamines: cetirizine, the active ingredient in Zyrtec.

When is the best time to take cetirizine?

Cetirizine can be taken at any time of the day. In most people it is non-sedating, so they take it in the morning. However, a percentage of people do find it to be sedating so if it does make you drowsy it is best to take it in the evening. Cetirizine can be taken with or without food.

Is it better to take antihistamines at night or in the morning?

For many people with allergies, symptoms are the worst around 4 a.m. to 6 a.m. Taking an antihistamine at bedtime may help you or your child feel better in the morning during allergy season.

What happens if you stop taking cetirizine?

For example, some people experience symptoms with cetirizine if they take it for a while and then stop suddenly. The main withdrawal symptom is called pruritus— itching and burning sensations of the skin ranging from moderate to severe.

Does cetirizine cause weight gain?

H1 receptor antihistamines such as cetirizine, fexofenadine, and desloratadine are among the most commonly prescribed medications for the treatment of allergies and have been shown to stimulate appetite and weight gain as side effects of treatment (6).

Can cetirizine be addictive?

People who take antihistamines regularly may build up a tolerance to the drug, which means they need to take higher and higher doses to get the same effect. This can lead to addiction. Antihistamines are often addictive because they work by blocking histamine receptors.

Can too much histamine cause depression?

Inflammation -- a blanket term describing an immune response -- triggers the release of histamine in the body. This increases blood flow to affected areas to flood them with immune cells. While these effects help the body fight infections, both long-term and acute inflammation is increasingly linked to depression.

Can high histamine cause depression?

In a study done at the Imperial college London and the University of South Carolina, it has been found that inflammation and release of the molecule histamine could be responsible for mood in the brain. This has become a molecule of interest where depression is a concern.

What does high histamine feel like?

The symptoms of histamine intolerance vary widely.

These include: Flushing, difficulty regulating body temperature, sudden excessive sweating. Hives, rashes, swelling, itchy skin, eczema. Racing heart, palpitations, arrhythmia.