Can an 80 year old survive lymphoma?

Overall 5-year survival for the whole group was 39%, and median survival time was 26 months. Conclusion: A high response rate can be achieved in very elderly NHL patients despite aggressive histology, poor prognostic features, and reduced doses of chemotherapy.
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Is lymphoma curable in elderly?

3 And, as Drs Bron and Soubeyran point out, the incidence of most subtypes of the disease “increase after the age of 50, with a median age of onset of 67 years.” Hodgkin lymphoma is considered one of the most treatable forms of the disease, with 5-year overall survival rates around 85%.
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Can a 90 year old survive lymphoma?

Conclusions: The median OS is short in 90+ patients diagnosed with lymphoma but some patients experience prolonged survival. Lymphoma represents the main cause of death in these patients. Treatment may improve survival of selected patients with aggressive but not indolent NHL.
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What is the most common lymphoma in the elderly?

Follicular lymphoma (FL) is the most common indolent non-Hodgkin lymphoma, which typically affects mature adults and elderly, whose median age at diagnosis is 65 years.
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How is lymphoma treated in the elderly?

More than 50% of elderly DLBCL patients can be expected to be cured by modern immunochemotherapy. The standard chemotherapy partner of rituximab is the CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) regimen.
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Lymphoma Patients who Remain Event-Free Two Years after Diagnosis have a Normal Life Expectancy



How long can an 80 year old live with lymphoma?

For those who are 80 or older:

around 65 out of 100 (around 65%) will survive their lymphoma for 5 years or more after they are diagnosed.
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Should an 80 year old have chemo?

First, there is no reason to deny older people adequate cancer therapy — surgery, chemotherapy, radiation — based on age alone. Individualization is critical; one size does not fit all! While one 80-year-old may tolerate a standard course of chemotherapy perfectly well, the next may not.
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What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia.

It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured.
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Why do old people get lymphoma?

Age. Lymphoma can develop at any age, but most types of non-Hodgkin lymphoma are more common in older people. This is because genetic changes in your cells (mutations) tend to build up throughout your life. Some of these changes can lead to lymphoma.
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How fast does lymphoma progress?

Low-Grade Lymphoma

These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
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What are the final stages of lymphoma?

Stage 4. Stage 4 is the most advanced stage of lymphoma. Lymphoma that has started in the lymph nodes and spread to at least one body organ outside the lymphatic system (for example, the lungs, liver, bone marrow or solid bones) is advanced lymphoma.
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How does lymphoma cause death?

People with NHL most often die from infections, bleeding or organ failure resulting from metastases. A serious infection or sudden bleeding can quickly lead to death, even if someone doesn't appear very ill.
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How is Hodgkin's lymphoma treated in the elderly?

The antibody-drug conjugate brentuximab vedotin is a very effective option for elderly patients with a high response rate albeit limited durability. Anti-programed cell death protein 1 antibodies might also be effective in elderly Hodgkin lymphoma patients with a mechanism of action distinct from chemotherapy.
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Is lymphoma common in older adults?

Lymphoma in very elderly patients is common because approximately half of all lymphoma cases occur in patients more than 65 years old and one‐third of reported cases are aged over 75 years.
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What are the warning signs of lymphoma?

Signs and symptoms of lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Shortness of breath.
  • Unexplained weight loss.
  • Itchy skin.
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Where does lymphoma spread to first?

NHL usually starts in an area of lymph nodes. When it spreads to an organ or tissue outside of the lymph nodes, it is called extranodal spread.
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Can you live a normal life with lymphoma?

It takes time but most people adjust well to life after a diagnosis of lymphoma and find a 'new normal'. This might involve making some changes to your everyday life.
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Does lymphoma spread quickly?

Non-Hodgkin lymphoma grows and spreads at different rates and can be indolent or aggressive. Indolent lymphoma tends to grow and spread slowly, and has few signs and symptoms. Aggressive lymphoma grows and spreads quickly, and has signs and symptoms that can be severe.
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Can lymphoma go away by itself?

Sometimes a provider may choose to wait and observe the involved lymph nodes, which will usually go away on their own if a temporary infection is causing the swelling. (However, some lymphomas may go away and appear to be benign, only to reappear at a later time.)
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Is chemo harder on older people?

If you are an older adult, chemotherapy might affect you differently than someone younger. For example, older adults have a greater risk of physical side effects from chemotherapy, which can affect your quality of life.
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Should an 80 year old have radiation therapy?

It has been suggested that psychosocial support during and after radiation therapy may improve overall quality of life. We found that in our patients who were age 80 or older, radiation therapy could be safely administered with both curative and palliative intent.
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Can elderly tolerate chemotherapy?

Organ toxicities may be more problematic in the elderly, but in most tumours, the efficacy of chemotherapy is not age dependent. Chemotherapy, where indicated for advanced cancer, can therefore be safely and effectively used in selected elderly patients.
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How long can you live with Stage 4 lymphoma?

It is important to note that everyone is different, and many people can live much longer than these estimates suggest. Overall, the 5-year survival rate for stage 4 Hodgkin lymphoma is 65 percent .
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