Can ALS be caused by stress?

Findings were that high stress, a type A personality, and physical activity were present more often in people with ALS.
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Does stress lead to ALS?

Psychological stress does not appear to play a part in the development of amyotrophic lateral sclerosis (ALS), with patients showing similar levels of prior stressful events, occupational stress, and anxiety as a control group, as well as higher resilience, a study shows.
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What is the root cause of ALS?

The cause of ALS is not known, and scientists do not yet know why ALS strikes some people and not others. However, scientific evidence suggests that both genetics and environment play a role in motor neuron degeneration and the development of ALS.
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Can ALS start with anxiety?

Between 1 and 4 years before the first record of ALS, only bipolar disorder, depression, and anxiety were associated.
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Can ALS be triggered?

Environmental factors, such as the following, might trigger ALS . Smoking. Smoking is the only likely environmental risk factor for ALS . The risk seems to be greatest for women, particularly after menopause.
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ALS: The cell under stress



Who is most likely to get ALS?

Most people who develop ALS are between the ages of 40 and 70, with an average age of 55 at the time of diagnosis. However, cases of the disease do occur in people in their twenties and thirties. ALS is 20% more common in men than women.
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Why so many athletes get ALS?

Researchers have hypothesized that vigorous physical activity might increase exposure to environmental toxins, facilitate the transport of toxins to the brain, increase the absorption of toxins, or increase the athlete''''s susceptibility to motor neuron disease through added physical stress.
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Does ALS start suddenly?

Rapid-onset ALS has symptoms that appear quickly. Limb-onset ALS starts with symptoms in arms or legs. Bulbar-onset ALS starts with trouble swallowing or speaking.
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Can depression cause ALS?

Depression and the subsequent risk of ALS.

Within 1 year after depression diagnosis, there was a 3.6-fold risk of ALS. Higher risk of ALS was also noted for the second and third years after depression diagnosis (table 3). The same pattern was seen for antidepressant use and “any depression” (table 3).
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Why is ALS becoming more common?

Here we show that the number of ALS cases across the globe will increase from 222,801 in 2015 to 376,674 in 2040, representing an increase of 69%. This increase is predominantly due to ageing of the population, particularly among developing nations.
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Is there a way to prevent ALS?

There is no definite method to prevent ALS. However, people with ALS can participate in clinical trials, the National ALS Registry, and the National ALS Biorepository. This participation may help researchers learn about potential causes and risk factors of the disease.
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Can exercise prevent ALS?

This study revealed that physical activity and ALS may be connected in a more complex way than previously considered. The researchers found that only those who had high levels of physical activity from their occupation—but not from leisure activities—had an increased risk of ALS.
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Can diet cause ALS?

Approximately 90% of ALS cases are sporadic, suggesting there are multiple contributing factors that influence the disease risk, onset, and progression. Diet and sex are two factors that have been reported to alter ALS risk, onset and progression in humans and in animal models, providing potential modifiers of disease.
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Can ALS be caused by emotional trauma?

Findings were that high stress, a type A personality, and physical activity were present more often in people with ALS.
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Can mental stress cause MND?

There is strong evidence that oxidative stress plays an important role in the pathogenesis of motor neurone disease (MND).
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What were your first ALS symptoms?

Bulbar onset usually affects voice and swallowing first. The majority of ALS patients have limb onset. For these individuals, early symptoms may include dropping things, tripping, fatigue of the arms and legs, slurred speech and muscle cramps and twitches.
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What are the symptoms of anxiety?

Signs and Symptoms
  • Feeling restless, wound-up, or on-edge.
  • Being easily fatigued.
  • Having difficulty concentrating.
  • Being irritable.
  • Having headaches, muscle aches, stomachaches, or unexplained pains.
  • Difficulty controlling feelings of worry.
  • Having sleep problems, such as difficulty falling or staying asleep.
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What is the progression of ALS?

As ALS progresses, most voluntary muscles become paralyzed. As the muscles of the mouth and throat, and those involved in breathing, become paralyzed, eating, speaking, and breathing is compromised. During this stage, eating and drinking are usually require a feeding tube. Breathing is assisted via a ventilator.
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How does ALS affect mental health?

Despite the low rates of clinical depression and anxiety, patients with ALS have been shown to be at increased risk of being diagnosed with depression, anxiety and other neurotic or stress-related disorders following diagnosis (21–25), however this may be attributable to the clinicopathological overlap between ALS and ...
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How long can you have ALS without knowing?

And what tests are needed to make the diagnosis? A: You're asking very important questions. And you're right; it takes on average about nine to 12 months for someone to be diagnosed with ALS, from the time they first began to notice symptoms.
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Does ALS show up in blood work?

Blood test: Blood tests can look for early signs of ALS and rule out other conditions.
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Can ALS go into remission?

Although symptoms may seem to stay the same over a period of time, ALS is progressive and does not go into remission. It is terminal, usually within 2-5 years after diagnosis, although some people have lived with ALS for 10 years or longer.
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How many ex NFL players have ALS?

The study included more than 19,400 NFL players who began playing football between 1960 and 2019. Of these, 38 were diagnosed with ALS, and 28 died during the study period.
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Can weightlifting cause ALS?

Frequent strenuous exercise increases the risk of developing motor neuron disease (MND)/ALS in certain people, new research from the University of Sheffield has found.
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How did Hawking live so long?

Stephen Hawking dies at 76

Jeffrey Elliott, chief of the neuromuscular disorders section at the University of Texas Southwestern Medical Center. “I think part of his longevity may have been because he had a slowly progressive form. Probably it was also due to the exclusive nursing and medical care that he received.”
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