Can a child have cystic fibrosis if neither parent has it?

A person must inherit two CF genes to have CF disease. When your child was conceived,* he or she received a CF gene from both you and your partner. A child can inherit CF only if both parents carry a CF gene (that is, each parent either has CF or is a carrier*) and both parents pass the CF gene on to their child.
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Can a baby have cystic fibrosis if neither parent is a carrier?

Cystic fibrosis is inherited. This means it is passed down from parent to child through the genes. Your baby inherited a normal CF gene (N) from one parent, and a mutation of a CF gene (C) from the other parent. This means at least one parent (mother or father) is also a CF carrier.
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Can you get CF if no one in your family has it?

Can my children have CF even if it is not in my family? Yes. In fact, most couples who have a child with CF have no family history of cystic fibrosis and are surprised to learn that they carry a mutation in the CFTR gene, which causes the condition.
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What if only one parent is a carrier of cystic fibrosis?

People with one CF gene are called carriers. If a parent is a carrier, there's a 50 percent chance they'll pass on the gene with a mutation to their child. If both parents pass on a normal gene, or only one parent passes a gene with a mutation, the child will not have CF.
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Which parent carries the gene for cystic fibrosis?

Cystic fibrosis (CF) is a genetic disease. This means that CF is inherited. A child will be born with CF only if two CF genes are inherited - one from the mother and one from the father. A person who has only one CF gene is healthy and said to be a "carrier" of the disease.
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What Is Cystic Fibrosis | Health | Biology | FuseSchool



What gender is more likely to get cystic fibrosis?

Males account for slightly more than 50 percent of all cases of cystic fibrosis (CF) but generally have better outcomes than females until about age 20. After that, men and women experience roughly equal outcomes for long-term survival. Still, males with CF tend to live an average of 2 years longer than females.
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Can CF skip a generation?

one in four (25%). Some parents think that if they have had one child with CF, their other children will be born without the disease. This is not always true. With every pregnancy, parents who both carry the CF gene will always have a one in four (25%) chance of having a child with CF.
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How accurate is genetic testing for cystic fibrosis?

A positive genetic carrier test for CF means that a person has an altered copy of the CF gene; this result is more than 99% accurate.
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What is the probability at least one child will inherit cystic fibrosis?

There is a 1-in-4 chance (25% of the time) the child will receive a CF gene from each parent (two abnormal genes total) and will be born with CF disease. There is a 2-in-4 chance (50% of the time) the child will receive 1 CF gene from 1 parent and a non-CF normal gene from the other parent.
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Can you test fetus for cystic fibrosis?

Is it possible to find out if a fetus has cystic fibrosis? Testing can be done to learn if a fetus has CF or is a carrier. This is called prenatal diagnostic testing. This testing can be done as early as 10 weeks of pregnancy.
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How do I know if I carry the cystic fibrosis gene?

The only way to know for sure if you are a cystic fibrosis carrier is to get genetic testing for CF. This is done by taking a blood sample or cells from your cheek, and then sending it out to a lab for DNA testing.
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Are you born with CF or can you develop it?

It's an inherited condition. A child needs to inherit one copy of the mutated gene from each parent to develop cystic fibrosis. If they only inherit one copy from one parent, they won't develop it. However, they will be a carrier of that mutated gene, so they could pass it along to their own children in the future.
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Who is most likely to get cystic fibrosis?

The disease occurs mostly in whites whose ancestors came from northern Europe, although it affects all races and ethnic groups. Accordingly, it is less common in African Americans, Native Americans, and Asian Americans. Approximately 2,500 babies are born with CF each year in the United States.
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How early do babies show symptoms of cystic fibrosis?

Babies born with CF often show symptoms in the first year. But some children may not show symptoms until later in life. The symptoms below may indicate CF, and babies with these symptoms may be tested for CF: Diarrhea that doesn't go away.
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Can one sibling be a carrier for cystic fibrosis?

Since all of our genes are inherited from our parents on their chromosomes, individuals who are cystic fibrosis carriers have inherited their non- working gene from one of their parents. This means that brothers and sisters of a carrier have a 50% chance to be a carrier.
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How long is the average lifespan of a person with cystic fibrosis?

Today, the average life span for people with CF who live to adulthood is about 44 years. Death is most often caused by lung complications.
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What is the main cause of cystic fibrosis?

Cystic fibrosis (CF) is a disease that is passed down through families. It is caused by a defective gene that makes the body produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas.
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What would be the best way to predict the probability of a baby having cystic fibrosis?

The greatest risk factor for cystic fibrosis is a family history of the disease, especially if either parent is a known carrier. The gene that causes cystic fibrosis is recessive. This means that in order to have cystic fibrosis, children must inherit two copies of the gene, one from each parent.
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Can you be diagnosed with cystic fibrosis late in life?

While most cystic fibrosis patients are diagnosed by the time they are two years old, and others are diagnosed in adulthood. It's important to recognize that there are more than 1,800 mutations in the cystic fibrosis gene, which may complicate the diagnosis.
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What test confirms cystic fibrosis?

A sweat test checks for high levels of chloride in your sweat. The sweat test is the standard test for diagnosing cystic fibrosis.
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How often is cystic fibrosis misdiagnosed?

Abstract. On reassessment of 179 children who had previously been diagnosed as having cystic fibrosis seven (4%) were found not to have the disease. The importance of an accurate sweat test is emphasised as is the necessity to prove malabsorption or pancreatic abnormality to support the diagnosis of cystic fibrosis.
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What are 5 symptoms of cystic fibrosis?

Symptoms of cystic fibrosis include:
  • lung infections or pneumonia.
  • wheezing.
  • coughing with thick mucus.
  • bulky, greasy bowel movements.
  • constipation or diarrhea.
  • trouble gaining weight or poor height growth.
  • very salty sweat.
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What is the oldest age someone has been diagnosed with cystic fibrosis?

Recently, more and more people have been diagnosed with CF after age 50. The oldest person in the United States diagnosed with CF for the first time was 82.
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Can two people with CF be close to each other?

That's why it's important for people with CF to stay at least 6 feet away from others with CF and anyone with a cold, flu, or infection. For people with CF, being close to others with the disease puts them at greater risk of getting and spreading dangerous germs and bacteria. This is called cross‐infection.
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What race is cystic fibrosis most common in?

Cystic fibrosis is a common genetic disease within the white population in the United States. The disease occurs in 1 in 2,500 to 3,500 white newborns. Cystic fibrosis is less common in other ethnic groups, affecting about 1 in 17,000 African Americans and 1 in 31,000 Asian Americans.
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