Are there any calcium channel blockers that don't cause edema?

Edema will diminish upon conversion from a dihydropyridine CCB to a nondihydropyridine CCB such as verapamil or diltiazem. In addition, the newer, third-generation dihydropyridine CCBs such as lacidipine,^[32,33] manidipine, and lercanidipine^{[32,33,34,35]} are regularly reported to cause less peripheral edema.

Which calcium channel blocker causes least edema?

Diltiazem, a non-DHP agent, seems to be associated with the lowest incidence of ankle oedema.

Which calcium channel blocker causes the most edema?

Pedal edema is one of the most common adverse effects of calcium antagonists. It has been observed with all available dihydropyridine agents, but it also seems to occur to a lesser extent with verapamil and diltiazem.

Do all CCBs cause edema?

The frequency with which CCB treatment is accompanied by peripheral edema is both compound-specific and dose-dependent. Therefore, a more potent CCB like amlodipine will be associated with higher rates of edema development than a somewhat lower-potency CCB like diltiazem.

Do calcium channel blockers cause fluid retention?

Objective: Peripheral edema is considered to be a common and annoying adverse effect of calcium channel blockers (CCBs). It has been thought to occur secondary to arteriolar dilatation causing intracapillary hypertension and fluid extravasation.

How do you stop leg swelling from amlodipine?

Ways to reduce swelling from amlodipine include: Non-pharmacological interventions, such as using a footstool to raise your legs as often as possible; regularly doing foot exercises to promote better movement and circulation.

What calcium channel blocker has the least side effects?

Should you stop taking amlodipine If your ankles swell?

In those taking higher dose (10mg) amlodipine, about 10 people in every 100 reported leg swelling (10%). Interestingly, women are more likely to get the swelling, and most people tolerate this well and do not have to discontinue the medication.

Does amlodipine cause edema?

Amlodipine and nifedipine are common drugs associated with vasodilatory edema. When used as monotherapy, calcium channel blockers (CCBs) are associated with a substantial risk of peripheral edema, including pedal edema, which is the most common reason for its discontinuation.

How do you treat peripheral edema calcium channel blockers?

A number of strategies exist to treat CCB-related edema, including switching CCB classes, reducing the dosage, and/or adding a known venodilator such as a nitrate, an angiotensin-converting enzyme inhibitor, or an angiotensin-receptor blocker to the treatment regimen.

Does amlodipine cause leg swelling?

Amlodipine (Norvasc) is a medication used to lower blood pressure. The higher the dose, the more likely you are to have swelling in both of your legs and feet. One in 10 patients experience swelling when taking amlodipine at a dose of 10 mg daily.

Does Cardizem cause leg swelling?

rash, edema (swelling of the legs and feet with fluid), low blood pressure (hypotension), drowsiness, and.

What is the best medication for edema?

More-severe edema may be treated with drugs that help your body expel excess fluid in the form of urine (diuretics). One of the most common diuretics is furosemide (Lasix).

What are the alternatives to calcium channel blockers?

ACE inhibitors, sartans, alpha-blockers and thiazide diuretics are all possible alternatives.

Which is better diltiazem or amlodipine?

Although both agents were well tolerated and reduced blood pressures consistently over the 10-week test period, amlodipine was more effective than diltiazem in reducing systolic and diastolic blood pressures to the target pressures of < 140 mm Hg systolic and < 90 mm Hg diastolic over a range of doses widely used in ...

What medication can be used instead of amlodipine?

How do you get rid of swollen ankles from blood pressure medicine?

Examples of some treatment options include: keeping the legs raised to improve blood flow. wearing compression stockings to reduce swelling. taking medications, such as aspirin.

Why does amlodipine make my feet swell?

Edema commonly occurs with calcium channel blockers because the drugs trigger the dilation of blood vessels. The dilation, in turn, lowers the blood pressure and improves the flow of blood throughout the body.

Can metoprolol cause swelling in feet and ankles?

Metoprolol may worsen the symptoms of heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing or heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain.

Which is the best calcium channel blocker?

Dihydropyridine calcium-channel blockers

For people with hypertension alone, amlodipine may be preferred on the basis of cost. For people with hypertension and angina, amlodipine, felodipine, and modified-release nifedipine may be preferred.

When should you not take calcium channel blockers?

Here are some things to consider if you and your doctor are deciding whether you should take a calcium channel blocker. You have allergies to foods or dyes. You are thinking of becoming pregnant, you are pregnant, or you are breast-feeding your baby. You are over 60.

Why do blood pressure tablets make your ankles swell?

Swelling in your ankles and feet is called peripheral edema. Many medications can cause this swelling. Calcium channel blockers, which help to manage blood pressure, are a common cause, especially a type called dihydropyridines.

Can chronic edema be cured?

The back-up of blood from these conditions causes pressure, which forces fluid from tiny capillaries in the area and into the surrounding tissues. These types of edema cannot be cured, so the goal is management. Exercise, particularly involving the affected limbs, can help veins return blood to the heart.

How do you drain edema naturally?