Are MS lesions permanent?

Even without medical treatment, brain lesions in MS don't simply keep growing and growing. “The body calms down these lesions and surrounds them, and they stop,” says Cross. If a lesion forms but doesn't develop past a certain point, it may cause few or even no symptoms.
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Do MS brain lesions go away?

Will MS brain lesions go away? It might be possible to one day heal lesions in addition to slowing the growth of them. Scientists are working to develop myelin repair strategies, or remyelination therapies, that might help regrow myelin.
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How long do MS lesions last?

Most symptoms develop abruptly, within hours or days. These attacks or relapses of MS typically reach their peak within a few days at most and then resolve slowly over the next several days or weeks so that a typical relapse will be symptomatic for about eight weeks from onset to recovery.
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Can MS lesions improve?

Can Lesions Heal Once They Appear? “Absolutely,” says Dr. Hua. “It's not specific to MS, but in any process where there's some sort of brain injury, there will always be healing, as well.
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Do MS lesions repair themselves?

With regular scans, a neurologist can tell how active your MS is, and to what extent your nerves are being damaged. Sometimes, lesions will repair themselves and not be seen on subsequent scans. Persistent lesions may eventually show up as 'black holes', where the underlying neuron has suffered irrepairable damage.
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Types of MS Lesions - National MS Society



Can MS lesions shrink?

Lesion accrual in multiple sclerosis (MS) is an important and clinically relevant measure, used extensively as an imaging trial endpoint. However, lesions may also shrink or disappear entirely due to atrophy.
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Do MS patients always have brain lesions?

About 5 percent of people who are confirmed to have MS do not initially have brain lesions evidenced by MRI. However, the longer a person goes without brain or spinal cord lesions on MRI, the more important it becomes to look for other possible diagnoses.
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Can MS stay mild?

After the first round of symptoms, multiple sclerosis can stay mild without causing major problems for decades, a 30-year British study indicates.
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Can MS disappear?

Relapsing-remitting MS is marked by relapses that last at least 24 hours. During a relapse, symptoms get worse. A relapse will be followed by a remission. During a remission, symptoms partly or completely go away.
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How many MS lesions are normal?

For the diagnosis of multiple sclerosis, there should be at least one typical multiple sclerosis lesion in at least two characteristic regions [periventricular (abutting the lateral ventricles), juxtacortical/cortical, infratentorial, spinal cord] to support dissemination in space (Thompson et al., 2018).
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Does MS ever stop progressing?

Over time, symptoms stop coming and going and begin getting steadily worse. The change may happen shortly after MS symptoms appear, or it may take years or decades. Primary-progressive MS: In this type, symptoms gradually get worse without any obvious relapses or remissions.
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Can you stop the progression of MS?

Multiple sclerosis (MS) is difficult to diagnose, and, as yet, it has no cure. However, according to new research, it may be possible to slow its progression without some of the health risks associated with current treatments.
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How quickly does MS deteriorate?

Between 8 and 9 of every 10 people with MS are diagnosed with the relapsing remitting type. Someone with relapsing remitting MS will have episodes of new or worsening symptoms, known as relapses. These typically worsen over a few days, last for days to weeks to months, then slowly improve over a similar time period.
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Does MS go away and come back?

People with multiple sclerosis (MS) tend to have their first symptoms between the ages of 20 and 40. Usually the symptoms get better, but then they come back. Some come and go, while others linger. No two people have exactly the same symptoms.
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What happens when MS lesions disappear?

"When the lesions decrease over time, it's not because the patient lesions are healing but because many of these lesions are disappearing, turning into cerebrospinal fluid."
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How often should you have MRI with MS?

New lesions might occur in patients with progressive MS and adjusting therapy can be considered. Patients with untreated CIS should be scanned every 1–3 months for the initial 6 months and if stable repeating MRIs every 6–12 months is recommended, unless new clinical symptoms occur.
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Is MS curable if caught early?

There's no drug or treatment yet that can cure MS. The drugs prescribed for people with MS usually target their overactive immune system; many different medications work this way. Is one of these drugs better than others? Not across the board, Keegan says.
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Can you lead a normal life with MS?

You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
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Can MS come and go?

MS symptoms can come and go and change over time. They can be mild, or more severe. The symptoms of MS are caused by your immune system attacking the nerves in your brain or spinal cord by mistake. These nerves control lots of different parts of your body.
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What is the mildest form of MS?

There's no cure for multiple sclerosis, but benign MS is the mildest form of the condition.
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Can you have MS for 20 years and not know it?

Benign MS can't be identified at the time of initial diagnosis; it can take as long as 15 years to diagnose. The course of MS is unpredictable, and having benign MS doesn't mean that it can't progress into a more severe form of MS.
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Does all MS become progressive?

Most people with relapsing-remitting MS -- about 80% -- eventually get secondary progressive MS. The relapses and remissions that used to come and go change into symptoms that steadily get worse. The shift typically begins 15 to 20 years after you're first diagnosed with MS.
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Can you feel brain lesions?

Typical symptoms may include: Headaches are usually the first symptom to appear with brain lesions. The pain appears suddenly and worsens as time passes. Over-the-counter medicine usually offers no relief for the pain.
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Is white matter the same as lesions?

Axons are surrounded by a fatty material called myelin, which insulates them like a sheath and gives white matter its color. Abnormalities in white matter, known as lesions, are most often seen as bright areas or spots on MRI scans of the brain. They can reflect normal aging; white matter deteriorates as people age.
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Can MS symptoms get worse without new lesions?

After a certain amount of time, “You look and see that you're not having the same kind of relapses, there are no new MRI lesions, but there are certain symptoms that are gradually getting worse,” Shephard says of her gradual change to secondary-progressive MS.
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