Are mRNA vaccines preferred over Johnson and Johnson vaccine for COVID-19?

In December 2021, the CDC updated its recommendations and stated that either of the two mRNA vaccines is preferred over the Johnson & Johnson (J&J) COVID-19 vaccine.
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Do mRNA Pfizer and BioNTech vaccines largely prevent severe disease from the COVID-19 Omicron variants?

Pfizer Inc. and BioNTechs Covid-19 vaccine appears to largely prevent severe disease from the coronavirus omicron variants sublineages BA. 4 and BA.
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Are mRNA COVID-19 vaccines safe?


mRNA vaccines are safe and effective.
mRNA vaccines have been held to the same rigorous safety and effectiveness standards as all other types of vaccines in the United States.

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What COVID-19 vaccines are using mRNA technology?


The vaccines made by Pfizer-BioNTech and Moderna use mRNA to fight COVID-19.

When these vaccines were rolled out, it was the first time mRNA was used on humans in vaccine technology. While the concept is new to the public, the research has been around since the early 1990s. What are mRNA Vaccines? 2/11

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Are severe reactions to mRNA COVID-19 vaccines common?


We found that reported reactions to mRNA vaccination were mostly mild in severity and transient in duration, and most reports were non-serious. Reactions and health impacts were reported more frequently in female than in male recipients, and in individuals younger than 65 years than in older individuals.

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What are some rare severe allergic reactions to mRNA COVID-19 vaccines?

“Overall, severe allergic reactions to COVID-19 mRNA vaccines, including life-threatening anaphylaxis reactions such as low blood pressure and difficulty breathing, are rare, on the order of five cases per million vaccine doses administered,” noted Dr. Guerrerio.
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Has anyone had severe reactions to the Moderna COVID-19 vaccine?


Monitoring of the Moderna COVID-19 vaccine has found 10 cases of anaphylaxis after the administration of 4,041,396 first doses of the Moderna COVID-19 vaccine. In 9 out of these 10 cases of anaphylaxis, the recipient of the vaccine had onset of symptoms within 30 min of administration.

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Are there any safety concerns concerning mRNA technology of the Pfizer-BioNTech COVID-19 Vaccine?

FDA does not have specific safety concerns with a vaccine that utilizes this technology.

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How long has the mRNA vaccine been around?

mRNA vaccines have been studied before for flu, Zika, rabies, and cytomegalovirus (CMV). As soon as the necessary information about the virus that causes COVID-19 was available, scientists began designing the mRNA instructions for cells to build the unique spike protein into an mRNA vaccine.
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Who makes Moderna's COVID-19 vaccine?


Manufacturer: ModernaTX, Inc.

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Do mRNA COVID-19 vaccines cause heart inflammation?


These cases typically occur in male adolescents and young adults after the second dose, and within a week of vaccination. It is important to seek medical care if symptomatic (chest pain, shortness of breath, having a fast beating, fluttering, or pounding heart).

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Are the COVID-19 vaccines safe?


All currently approved or authorized COVID-19 vaccines are safe and effective and reduce your risk of severe illness. Vaccination can reduce the spread of disease, which helps protect those who get vaccinated and the people around them.

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Are long-term side effects possible with COVID-19 vaccination?


Serious side effects that could cause a long-term health problem are extremely unusual following any vaccination, including COVID-19 vaccination. The benefits of COVID-19 vaccination outweigh the known and potential risks.

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Does the COVID-19 booster vaccine protect against the Omicron variant?


In adult populations, the protection conferred by two vaccine doses against Covid-19 wanes (more against milder infection than against severe disease) and is lower for omicron than for delta. However, a booster dose increases protection, including protection against omicron.

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Is the COVID-19 Omicron variant more transmissible than previous variants?

The good news was that the new variant caused less severe illness and death than Delta. But it was also highly transmissible—more contagious than any variant that came before it.
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Does the COVID-19 booster protect you from the omicron variant?


A COVID-19 booster shot will provide strong and broad antibody protection against the range of omicron sublineage variants of the SARS-CoV-2 virus in circulation, two new studies using serum from human blood samples suggest.

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Will a COVID-19 vaccine alter my DNA?

No. COVID-19 mRNA vaccines do not change or interact with your DNA in any way.
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How long does COVID-19 rebound last?

So far there have been no reports of severe illness in those who have experienced covid rebound, and most people seem to recover and stop testing positive around three days later without needing additional covid-19 treatment.
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What are the average ages of people who had myocarditis after mRNA-based COVID-19 vaccination during the first 8 months of 2021?

Of the 1626 reports that met the CDCs case definition for myocarditis, 1195 (73%) were younger than 30 years of age, 543 (33%) were younger than 18 years of age, and the median age was 21 years (IQR, 16-31 years) (Figure 1).
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Is it safe to take the Moderna, Pfizer-BioNTech, or J&J COVID-19 vaccine during pregnancy?

No safety concerns were found in animal studies: Studies in animals receiving a Moderna, Pfizer-BioNTech, or Johnson & Johnson (J&J)/Janssen COVID-19 vaccine before or during pregnancy found no safety concerns in pregnant animals or their babies.
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Is the Pfizer COVID-19 vaccine safe?


Pfizer-BioNTech COVID-19 Vaccine Ingredients. All COVID-19 vaccine ingredients are safe. Nearly all of the ingredients in COVID-19 vaccines are ingredients found in many foods – fats, sugars, and salts. The Pfizer-BioNTech COVID-19 vaccine (COMIRNATY) also contains a harmless piece of messenger RNA (mRNA).

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What are some of the common side effects of COVID-19 vaccines?

  • Injection-site pain occurred after dose 1 in 66.2% of participants and 68.6% after dose 2.
  • One third of participants (33.9%) reported fatigue after dose 1 and 55.7% after dose 2.
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Is it normal that I feel worse after second COVID-19 shot?


This is normal and expected, but it doesn't happen to everyone. Even if you feel worse after the second shot, the side effects should still resolve within a few days.

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What should I do if I have a severe allergic reaction to the COVID-19 vaccine?

If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911.
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Why do people who had COVID-19 have a strong reaction to the vaccine?


The next time you encounter the pathogen, these responses will kick in faster and stronger, because your immune system is already primed to recognise and respond to it. This is why people who have already recovered from COVID-19 may experience more of these mild reactions.

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