Are antidepressants safe long-term?

Antidepressants, specifically SSRIs which are considered the most tolerable and are therefore the most prescribed, are generally safe to take long-term.

Is it okay to be on antidepressants for years?

Long-term—even indefinite—use of antidepressants may be the best treatment for someone with multiple past episodes of depression, especially if they have a history of suicide attempts or have residual symptoms, like sleep problems, says Dr. Potash.

Can you stay on antidepressants for life?

MYTH: Once on antidepressants, I'll be on them for life. FACT: Not true. A general rule clinicians often use is that a person should be treated with antidepressants at least one-and-a-half times as long as the duration of the depressive episode before they can begin to be weaned off.

How long is it safe to stay on antidepressants?

Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you've had three or more recurrences of depression, make that at least two years.

Does your brain go back to normal after antidepressants?

"The fact that antidepressant withdrawal can be so prolonged suggests that the drug has changed the brain and that those changes are taking a very long time to return to normal and it may be the case that sometimes they don't go back to normal."

The 'extreme' side-effects of antidepressants - BBC News

Are antidepressants worth it?

In other words, antidepressants improved symptoms in about an extra 20 out of 100 people. Antidepressants can also relieve long-term symptoms of chronic depressive disorder (dysthymia) and chronic depression, and help make them go away completely. An antidepressant can already have an effect within one or two weeks.

Do antidepressants damage your brain?

We know that antipsychotics shrink the brain in a dose-dependent manner (4) and benzodiazepines, antidepressants and ADHD drugs also seem to cause permanent brain damage (5).

Is it hard to get off antidepressants?

It can be hard to stop taking antidepressants after taking them for a long time. People should seek a doctor's advice and support when planning to stop using these medications. The doctor will help make a plan that may involve reducing the dosage gradually or switching to another drug.

What are long-term effects of antidepressants?

Two recent reviews of research in this area concluded that discontinuation effects, sexual dysfunction, weight gain, and sleep disturbance (multiple long-wake periods) are adverse effects of long-term SSRI use.

Do antidepressants heal the brain?

Scientists have long known that SSRIs rapidly increase the available amount of the neurotransmitter serotonin, leading to changes that go well beyond brain chemistry: Research suggests the drugs help reverse the neurological damage associated with depression by boosting the brain's innate ability to repair and remodel ...

What is the truth about antidepressants?

In general, antidepressants work really well, especially when used along with psychotherapy. This combination may give you better results than using either treatment alone. Most people on antidepressants say they have eventual improvements in symptoms such as sadness, loss of interest, and hopelessness.

Do antidepressants affect intelligence?

Serretti et al. showed that using SSRIs even in healthy individuals leads to cognitive impairment [25]. The memory loss caused by SSRIs has not yet been convincingly explained; however, serotonin appears to play an important role in learning and memory [26].

How do you know when to go off antidepressants?

Your doctor might recommend stopping your antidepressant if: You're feeling better, and you and the doctor agree that it's time to stop. You have been taking the medicine for at least 6 months.

What are the benefits of coming off antidepressants?

Because some medical professionals theorize that antidepressants increase hunger and food cravings by adjusting neurotransmitters, it's possible that stopping antidepressants could make you feel less hungry.

What percentage of the population is on antidepressants?

Summary. During 2015–2018, 13.2% of Americans aged 18 and over reported taking antidepressant medication in the past 30 days. Antidepressant use was higher among women than men in every age group. Use increased with age, in both men and women.

Does brain fog from antidepressants go away?

These symptoms of brain fog may be short-term or ongoing as you take these medications. While antidepressants are generally intended to help with brain fog, some can cause brain fog as a side effect, depending on the medication and your unique response to it.

How can I get off antidepressants naturally?

Never stop "cold turkey." In many cases, the best way to stop taking most antidepressants is to slowly cut back your dose under the guidance of your doctor. This is called tapering. Tapering helps your brain adjust to the chemical changes and can help prevent discontinuation symptoms.

Can I go back on antidepressants after stopping?

Experts say some people need to keep taking antidepressants longer, while others can avoid relapses after stopping their medication use. They say people who do stop taking antidepressants should consult with their doctor first and perhaps participate in therapy sessions for at least a while.

Do antidepressants cause dementia?

Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer's Society and published today in the British Medical Journal.

What happens if you stop antidepressants?

It might seem like you don't need the medication anymore, but if you stop taking it, the medicine will leave your body and your symptoms might return. Quitting without consulting your doctor can be life-threatening. Suicide is a serious concern. It can also trigger withdrawal symptoms and relapse of your depression.

Do antidepressants change your personality?

Fact: When taken correctly, antidepressants will not change your personality. They will help you feel like yourself again and return to your previous level of functioning.

Do antidepressants do more harm than good?

Our review supports the conclusion that antidepressants generally do more harm than good by disrupting a number of adaptive processes regulated by serotonin. However, there may be specific conditions for which their use is warranted (e.g., cancer, recovery from stroke).

What are the cons of taking antidepressants?

Are antidepressants harmful?

Major adverse effects attributed to the tricyclic antidepressant drugs (TCAs) include conduction defects and lethal overdose. Most worrisome with the selective serotonin reuptake inhibitor drugs (SSRIs) is the serotonin syndrome. Although rare, this syndrome can be insidious and lethal.

Can antidepressants make you mean or angry?

SSRIs are the first line of therapy for anxiety and depressive disorders and for many other clinical diagnoses. One of the most disturbing side effects that is observed is a tendency towards aggressiveness among patients receiving medications from this group, mainly during the first month of therapy.