What are 3 characteristics of a pathogen that influence virulence?

By 1949, toxigenicity, infectivity, communicability, and inva- siveness were each considered to be attributes of virulence [4]. Replication and transmission. Contagiousness has been considered to be as important as replication for certain mi- crobes to persist in their hosts [18].
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What are 3 types of virulence factors?

Specific Virulence Factors
  • Adherence and Colonization Factors. To cause infection, many bacteria must first adhere to a mucosal surface. ...
  • Invasion Factors. ...
  • Capsules and Other Surface Components. ...
  • Endotoxins. ...
  • Structure of Endotoxin.
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What are the characteristics of virulence?

Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most contexts, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism—its ability to cause disease—is determined by its virulence factors.
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What are pathogen virulence factors?

A pathogen's ability to infect or damage its host tissues is determined by the virulence factors. These are often molecules synthesized by the bacteria or virus and encoded in their genome, but may also be acquired from the environment via transmissible genetic elements.
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How many virulence factors are there?

There are three general experimental ways for the virulence factors to be identified: biochemically, immunologically, and genetically.
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Virulence factors



What are virulence factors quizlet?

Virulence factors. Products needed by pathogens to infect. normal people and cause disease.
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What determines the virulence of a virus?

Virus virulence and host susceptibility are interdependent properties that are determined by the virus–host combination and that together result in the manifestations of infection.
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Which of the following virulence factors contributed to the pathology described in the case?

Which of the following virulence factors contributed to the pathology described in the case? Membrane-damaging toxins interfered with host immune function, allowing the pathogen time to replicate. Collagenase helped the pathogen breakdown tissues in the patient's arm to promote invasion.
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What features increase the virulence of a bacteria?

Bacterial characteristics that reduce host health and/or survival are considered “virulence factors.” Such factors include structural features like flagella and pili that facilitate attachment to host cells (Josenhans and Suerbaum, 2002; Kazmierczak et al., 2015), as well as secreted products like toxins and enzymes ...
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What factors determine the virulence of an organism quizlet?

Ch 15: Virulence factors
  • Dose - only need a small dose of organisms to cause a disease. ...
  • Adhesion to host cell - microbes stick to host. ...
  • Invasion of host cell. ...
  • Biofilm. ...
  • Capsule. ...
  • Enzyme - acts directly on host molecule.
  • Antigenic variation - antigen on the surface of microbe changes to trick the immune system.
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What are some examples of virulence factors?

Virulence factor refers to the components or structure of microorganism that helps in establishment of disease or infection.
...
Some examples of virulence factors are:
  • Attachment factors/ Adhesins.
  • Anti-phagocytic factors.
  • Spreading factors and enzymes.
  • Toxins; exotoxin and endotoxin.
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What are the virulence factors of bacterial and viral pathogens?

Virulence factors contribute to a pathogen's ability to cause disease. Exoenzymes and toxins allow pathogens to invade host tissue and cause tissue damage. Bacterial toxins include endotoxin and exotoxins. Endotoxin is the lipid A component of the LPS of the gram-negative cell envelope.
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What are the virulence factors in pathogenic bacteria and fungi?

Pathogenesis. Virulence factors characterized as important for attachment and invasion in human infection are CPS, β-hemolysin, C proteins, and pilus-like proteins. Experimental models of infection have demonstrated that antibodies to these surface structures are protective.
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Which of the following virulence factors contribute s to the ability of S. aureus to invade the body?

The virulence factors of Staphylococcus aureus include antigens, enzymes and toxins like: Antigens: Capsule. Adhesins.
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What virulence means?

Virulence is defined by the ability of a microorganism to cause disease in the host. Food can carry microorganisms that are virulent and are able to cause disease in the individuals who consume the food.
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Which of the following are virulence factors of S. aureus?

It is well known that S. aureus produces many virulence factors, such as hemolysins, leukocidins, proteases, enterotoxins, exfoliative toxins, and immune-modulatory factors (11, 12, 21, 31). The expression of these factors is tightly regulated during growth.
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Are enzymes virulence factors?

Therefore, certain housekeeping enzymes may act as putative virulence factors and targets for the development of new strategies to control the infection by using agents that can block their secretion and/or reassociation.
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What is an example of a virulence factor that is related to immune system evasion quizlet?

What is an example of a virulence factor that is related to immune system evasion? examples of virulence as an evolving property: -The 1918 influenza pandemic primarily killed young adults rather than elderly persons which is more typical of influenza both before and after that time.
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When the resident microbiota prevents the establishment of a pathogen what is it called?

Microbial antagonism occurs when members of the normal microbiota prevent pathogens from colonizing and becoming established in the body.
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Which of the following would be a portal of entry?

Portals of entry into the human body include: Inhalation (via the respiratory tract) Absorption (via mucous membranes such as the eyes) Ingestion (via the gastrointestinal tract)
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Which of the following are the most common members of the normal flora of the mouth?

which of the following are the most common members of normal flora of the mouth? Streptococcus mutans.
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How can we distinguish virulence from pathogenicity quizlet?

What is the difference between virulence and pathogenesis? Virulence is a quantitative description of how harmful a pathogen is, while pathogenesis describes the process of infection and the different components that contribute to carrying, transmitting, acquiring and developing an infection.
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What is the difference between virulence and pathogenesis?

Specifically, pathogenicity is the quality or state of being pathogenic, the potential ability to produce disease, whereas virulence is the disease producing power of an organism, the degree of pathogenicity within a group or species.
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What is highly virulent?

1a : marked by a rapid, severe, and destructive course a virulent infection. b : able to overcome bodily defensive mechanisms : markedly pathogenic virulent bacteria. 2 : extremely poisonous or venomous. 3 : full of malice : malignant virulent racists. 4 : objectionably harsh or strong virulent criticism.
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What causes high virulence?

However, in this system we found virulence to be very tightly correlated with viral load. This suggests virulence is a direct consequence of the damage caused by high parasite burdens, although it could also result from viral virulence factors resulting in the high viral loads.
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