Why is the 3/5 strand called the lagging strand quizlet?

This is because the phosphate group at the 5' end of the new strand and the 3' -OH group on the nucleoside triphosphate will not both fit in the active site of the polymerase. DNA replication always begins at an origin of replication.
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Why is the 3/5 strand called the lagging strand quizlet?

One of the strands is oriented in the 3' to 5' direction (towards the replication fork), this is the leading strand. The other strand is oriented in the 5' to 3' direction (away from the replication fork), this is the lagging strand.
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Why is the strand called the lagging strand?

The lagging strand is called the lagging strand because there is a substantial delay in the replication of that strand relative to the leading strand. That is, it literally "lags" behind the leading strand in the course of dsDNA replication.
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Why is one strand called the lagging strand quizlet?

One strand is synthesized continuously, in the same direction that helicase opens the double helix, and is known as the leading strand. The other strand is synthesized discontinuously, in the direction opposite that of helicase movement, and is known as the lagging strand.
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Why is the 3/5 template DNA strand called the leading strand?

One new strand, which runs 5' to 3' towards the replication fork, is the easy one. This strand is made continuously, because the DNA polymerase is moving in the same direction as the replication fork. This continuously synthesized strand is called the leading strand.
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Leading strand vs. lagging strand



Why is it called 3 and 5 end?

Each end of DNA molecule has a number. One end is referred to as 5' (five prime) and the other end is referred to as 3' (three prime). The 5' and 3' designations refer to the number of carbon atom in a deoxyribose sugar molecule to which a phosphate group bonds.
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What is the lagging strand of DNA also called?

The short, lagging strand fragments are called 'Okazaki fragments'. Figure 2. Both daughter DNA strands are replicated at the same time and in the 5′–3′ direction, but leading strand replication is continuous and lagging strand replication is discontinuous (a).
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Why are Okazaki fragments are made only on the 5 to 3 strand quizlet?

They are formed on the lagging strand of DNA. While DNA is synthesized continuously on the leading strand, Okazaki fragments are formed on the lagging strand because DNA synthesis always proceeds in the 5' to 3' direction.
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What is a lagging strand quizlet?

lagging strand. A discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5' to 3' direction away from the replication fork. DNA polymerase III. forms a phosphodiester bond to permanently incorporate the incoming DNA nucleotide into the new strand of DNA.
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What is meant by the lagging strand and why does that occur?

A lagging strand is one of two strands of DNA found at the replication fork, or junction, in the double helix; the other strand is called the leading strand. A lagging strand requires a slight delay before undergoing replication, and it must undergo replication discontinuously in small fragments.
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Is the lagging strand synthesized 5 to 3?

Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
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Why is there a lagging strand during DNA replication?

Explanation: The lagging strand exists because DNA is antiparallel and replication always occurs in the 5' to 3' direction.
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Why is the lagging strand discontinuous?

On the upper lagging strand, synthesis is discontinuous, since new RNA primers must be added as opening of the replication fork continues to expose new template. This produces a series of disconnected Okazaki fragments.
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What is the difference between the leading strand and the lagging strand in DNA replication quizlet?

What is the difference between the leading strand and the lagging strand in DNA replication? The leading strand is synthesized in the 3' → 5' direction in a discontinuous fashion, while the lagging strand is synthesized in the 5' → 3' direction in a continuous fashion.
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What is the difference between the leading strand and the lagging strand?

The separated DNA strands form a replication fork, where both the DNA strands get replicated forming a lagging and leading strand. The major difference between a lagging and leading strand is that the lagging strand replicates discontinuously forming short fragments, whereas the leading strand replicates continuously.
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Why is the lagging strand discontinuous quizlet?

On the lagging strand, since DNA moves from the 3' to 5' end, the synthesis is discontinuous because DNA polymerase III can only move from the 5' to the 3' and multiple primers are needed to synthesize the other strand from the origin of replication to the replication fork.
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Which strand is the lagging strand?

The lagging strand is the second strand of the DNA double helix. The strand opens up in the 5' to 3' direction. Therefore, the new strand growth has to occur away from the replication fork as the direction of DNA replication occurs only in the 5' to 3' direction.
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What are the fragments called on the lagging strand?

Okazaki fragments are pieces of DNA that are transient components of lagging strand DNA synthesis at the replication fork.
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How are the leading and lagging strands different quizlet?

the leading strand is synthesized continuously and in the same direction as the movement of the replication fork, while the lagging strand is synthesized in short fragments that are ultimately stitched together, in the opposite direction.
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Why are Okazaki fragments only found on the lagging strand?

Okazaki fragments are formed on the lagging strand for the synthesis of DNA in a 5′ to 3′ direction towards the replication fork. Only one of the two strands of DNA would be replicated in an entity if not for these fragments. This would reduce the efficiency of the process of replication.
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Why are Okazaki fragments made on the lagging strand quizlet?

Why are they only formed on the lagging strand, not the leading strand? The segments of the lagging strand. The Okazaki fragments are formed because the lagging strands are made of the discontinued fragments.
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How is the lagging strand built?

The lagging strand is synthesized discontinuously by DNA polymerase in sections called Okazaki fragments. These fragments are later connected together by DNA ligase to form a complete complementary strand.
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Why is it called a 3 prime end?

The 3′-end (three prime end) of a strand is so named due to it terminating at the hydroxyl group of the third carbon in the sugar-ring, and is known as the tail end.
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Why is it called 5 prime?

Glossary:5' (5-prime) A term that identifies one end of a single-stranded nucleic acid molecule. The 5' end is that end of the molecule which terminates in a 5' phosphate group. The 5' direction is the direction toward the 5' end.
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When you see 3 and 5 this is referring to the nucleic acids?

The 5' and 3' specifically refer to the 5th and 3rd carbon atoms in the deoxyribose/ribose sugar ring. The phosphate group attached to the 5' end of one nucleotide and the hydroxyl group at the 3' end of another nucleotide have the potential to form phospodiester bonds, and hence link adjacent nucleotides.
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