Which is more serious basal cell or squamous cell carcinoma?

Though not as common as basal cell (about one million new cases a year), squamous cell is more serious because it is likely to spread (metastasize). Treated early, the cure rate is over 90%, but metastases occur in 1%–5% of cases. After it has metastasized, it's very difficult to treat.
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Is squamous cell carcinoma more malignant than basal cell carcinoma?

Squamous cell cancers can usually be removed completely (or treated in other ways), although they are more likely than basal cell cancers to grow into deeper layers of skin and spread to other parts of the body.
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Which grows faster basal cell or squamous cell carcinoma?

SCC is generally faster growing than basal cell cancers. About 20 out of every 100 skin cancers (20%) are SCCs. They begin in cells called keratinocytes, which are found in the epidermis. Most SCCs develop on areas of skin exposed to the sun.
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Is squamous cell or basal cell carcinoma more common?

Basal cell carcinoma and squamous cell carcinoma are the two most common types of skin cancers. According to the American Cancer Society, over 5 million cases of basal cell and squamous cell cancers are diagnosed every year. Though, basal cell carcinoma occurs more often, taking credit for about 80% of these cases.
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What is the difference between basal cell carcinoma and squamous cell carcinoma?

Basal cell carcinoma most commonly appears as a pearly white, dome-shaped papule with prominent telangiectatic surface vessels. Squamous cell carcinoma most commonly appears as a firm, smooth, or hyperkeratotic papule or plaque, often with central ulceration.
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Dermatology - basal cell carcinoma and squamous cell carcinoma



How serious is a squamous cell carcinoma?

Squamous cell carcinoma of the skin is usually not life-threatening, though it can be aggressive. Untreated, squamous cell carcinoma of the skin can grow large or spread to other parts of your body, causing serious complications.
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What is the survival rate for squamous cell carcinoma?

In general, the squamous cell carcinoma survival rate is very high—when detected early, the five-year survival rate is 99 percent. Even if squamous cell carcinoma has spread to nearby lymph nodes, the cancer may be effectively treated through a combination of surgery and radiation treatment.
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What are the chances of dying from squamous cell carcinoma?

Compared with skin BCCs, skin SCCs not only are more likely to metastasize but also to cause mortality. Although the case-fatality rate is only approximately 1%, the national NMSC mortality figures equal or exceed those for melanoma, which is far more lethal but less common.
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How long does squamous cell carcinoma take to metastasize?

Prior studies have demonstrated metastasis rates of 3-9%, occurring, on average, one to two years after initial diagnosis [6].
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How long can you wait to treat squamous cell carcinoma?

The median patient delay was 2 months. The highest quartile patients reported > 9 months between noticing the lesion and the first visit, defined as long patient delay. The median treatment delay was 2 months. The highest quartile patients reported > 4 months treatment delay, defined as long treatment delay.
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How long does it take for basal cell carcinoma to metastasize?

In one review of 170 cases, the median interval between onset of BCC and metastasis was 9 years, with a range of less than 1 year to 45 years. Despite the long period from onset to metastasis, the tumor behaves aggressively once metastasis occurs.
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What are the warning signs of basal cell carcinoma?

Basal Cell Carcinoma Warning Signs and Symptoms
  • A small spot with an indentation in the center.
  • Scaly patch, especially near the ears.
  • Sore that either doesn't heal or heals but keeps returning.
  • Round growth that can be pink, red, brown, tan, black, or skin-colored.
  • Scar-like skin that isn't from an injury.
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Is Mohs surgery serious?

Mohs surgery is generally considered very safe, but there are some risks: Bleeding from the site of surgery. Bleeding into the wound (hematoma) from surrounding tissue. Pain or tenderness in the area where skin was removed.
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Can basal or squamous cell turn into melanoma?

Basal cell carcinoma does not progress into melanoma. Each is a separate and distinct type of skin cancer. Basal cell carcinoma is the most common form of skin cancer and one of two major nonmelanoma skin cancer types (the other is squamous cell carcinoma).
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Can basal cell carcinoma change to squamous cell carcinoma?

A history of basal cell carcinoma may also increase the chance of developing other types of skin cancer, such as squamous cell carcinoma.
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How do you know if squamous cell carcinoma has spread?

How to Tell If Squamous Cell Carcinoma Has Spread
  • The tumor is thicker than 2 millimeters.
  • The tumor has grown into the lower dermis or subcutis layers of the skin.
  • The tumor has grown into the nerves in the skin.
  • The tumor is present on the ear or on a hair-bearing lip.
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Where does squamous cell carcinoma spread first?

Hanke: The first place SCCs metastasize to is the regional lymph nodes. So if you have a squamous cell carcinoma on your cheek, for example, it would metastasize to the nodes in the neck.
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What organs does squamous cell carcinoma affect?

Squamous cell carcinomas can form on your skin (epidermis) in the same way BCC does, but SCC can also form where you have mucus membranes on your body, which includes the inside of your mouth, throat, lungs and genitals.
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How long can you live with untreated squamous cell?

Once squamous cell carcinoma has spread beyond the skin, though, less than half of people live five years, even with aggressive treatment. There are many ways to treat squamous cell carcinoma that has not spread. These include: cutting away the cancer and a small amount of healthy tissue around it.
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How long can you live with basal cell carcinoma?

The 5-year relative survival for BCC is 100%. This means that, on average, all of the people diagnosed with BCC are just as likely to live at least 5 years after their diagnosis as people in the general population. The 5-year relative survival for SCC is slightly less at 95%.
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Is basal cell carcinoma fatal?

Basal cell cancer is the most common form of skin cancer, accounting for nearly 80% of all skin cancers. Basal cell cancers arise from abnormal basal cells in the skin. It is rarely fatal, but it can be locally aggressive.
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Should squamous cell carcinoma be removed?

Basal or squamous cell skin cancers may need to be removed with procedures such as electrodessication and curettage, surgical excision, or Mohs surgery, with possible reconstruction of the skin and surrounding tissue. Squamous cell cancer can be aggressive, and our surgeons may need to remove more tissue.
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How long does it take to recover from squamous cell carcinoma surgery?

The wound may take 3 to 6 weeks to heal. How long it takes depends on the size of the area treated. Good wound care may help the scar fade with time.
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What is the most common treatment for squamous cell carcinoma?

Surgery
  • Mohs Surgery. Mohs surgery has the highest cure rate of all therapies for squamous cell carcinomas. ...
  • Curettage and Electrodessication. This very common treatment for squamous cell carcinoma is most effective for low-risk tumors. ...
  • Cryosurgery. ...
  • Laser Surgery.
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What type of chemo is used for squamous cell carcinoma?

One drug that is commonly used for topical chemotherapy to treat squamous cell carcinoma is fluorouracil (5-FU). This drug is: Available in cream or lotion form. Applied by a patient at home over the course of approximately three to six weeks.
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