What is the most effective vaccine ever?

Smallpox vaccination with vaccinia virus is the most famous example of a highly effective vaccine and at the time when people were faced with smallpox outbreaks, this vaccine was associated with each of these characteristics that led to the implementation of a successful vaccine.
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What are the most successful vaccines?

Here are five of the most important vaccines ever developed:
  • The smallpox vaccine. Smallpox was the first successful vaccine, developed in 1796 by Edward Jenner. ...
  • The polio vaccine. ...
  • The MMR vaccine. ...
  • The Tdap vaccine. ...
  • The HPV vaccine. ...
  • Insider's takeaway.
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What is the most important vaccine?

1. Tdap or Td. Tetanus, diphtheria, and pertussis (whooping cough) are highly contagious and life-threatening, especially for infants under six weeks of age. You may have received the Tdap vaccine when you were a child.
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Is the polio vaccine 100% effective?

Two doses of inactivated polio vaccine (IPV) are 90% effective or more against polio; three doses are 99% to 100% effective.
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Which viruses have successful vaccines?

  • Polio. Polio is a crippling and potentially deadly infectious disease that is caused by poliovirus. ...
  • Tetanus. Tetanus causes painful muscle stiffness and lockjaw and can be fatal. ...
  • The Flu (Influenza) ...
  • Hepatitis B. ...
  • Hepatitis A. ...
  • Rubella. ...
  • Hib. ...
  • Measles.
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WATCH: Which COVID vaccine is most effective?



Does polio still exist?

Is it curable? Polio does still exist, although polio cases have decreased by over 99% since 1988, from an estimated more than 350 000 cases to 22 reported cases in 2017. This reduction is the result of the global effort to eradicate the disease.
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Which disease is completely eradicated from world?

The last known natural case was in Somalia in 1977. In 1980 WHO declared smallpox eradicated – the only infectious disease to achieve this distinction.
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How effective is the TB vaccine?

Key vaccine facts

This vaccine gives protection against tuberculosis (TB) infection. It is 70-80% effective against the most severe forms of TB, such as TB meningitis. However, it is less effective in preventing the form of TB that affects the lungs.
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How effective is the HPV vaccine?

The trials that led to approval of Gardasil 9 found it to be nearly 100% effective in preventing cervical, vulvar, and vaginal infections and precancers caused by all seven cancer-causing HPV types (16, 18, 31, 33, 45, 52, and 58) that it targets (10).
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How effective is the tetanus vaccine?

A complete vaccine series has a clinical efficacy of virtually 100% for tetanus and 97% for diphtheria. A complete series is 3 doses for people 7 years or older and 4 doses for children younger than 7. In regard to pertussis, there has been an overall increasing trend in reported cases since the 1980s.
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What is the oldest vaccine?

The smallpox vaccine is the first vaccine to be developed against a contagious disease. In 1796, the British doctor Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus.
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Which vaccine is the safest?

The Pfizer and Moderna vaccines are strongly recommended as safe and effective at preventing serious illness or death from COVID-19. From December 2020 to December 2021, about 470 million doses of COVID-19 vaccine have been given in the U.S.
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What are the 6 killer diseases?

These six are the target diseases of WHO's Expanded Programme on Immuni- zation (EPI), and of UNICEF's Univer- sal Childhood Immunization (UCI); measles, poliomyelitis, diphtheria, pertussis (whooping cough), tetanus and tuberculosis.
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Which is better Pfizer or Moderna?

While both vaccines were highly effective in preventing infection, hospitalization and death, the Moderna vaccine conferred a 21% lower risk of infection and a 41% lower risk of hospitalization. “Both vaccines are incredibly effective, with only rare breakthrough cases,” said research team member Dr.
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Does the smallpox vaccine last a lifetime?

Length of Protection

Smallpox vaccination provides full immunity for 3 to 5 years and decreasing immunity thereafter. If a person is vaccinated again later, immunity lasts even longer. Historically, the vaccine has been effective in preventing smallpox infection in 95% of those vaccinated.
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Is polio eradicated?

The United States has been polio-free since 1979, thanks to a successful vaccination program. However, poliovirus is still a threat in some countries. Get your child vaccinated on schedule to help keep the U.S. polio-free.
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What are the 5 types of vaccines?

The main types of vaccines that act in different ways are:
  • Live-attenuated vaccines.
  • Inactivated vaccines.
  • Subunit, recombinant, conjugate, and polysaccharide vaccines.
  • Toxoid vaccines.
  • mRNA vaccines.
  • Viral vector vaccines.
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Is HPV a lifetime vaccine?

Studies suggest that HPV vaccines offer long-lasting protection against HPV infection and therefore disease caused by HPV infection. Studies of the bivalent and quadrivalent vaccines have followed vaccinated individuals for more than 10 years and have found no evidence of protection decreasing over time.
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What are the 4 main types of vaccines?

Inactivated vaccines. Live-attenuated vaccines. Messenger RNA (mRNA) vaccines. Subunit, recombinant, polysaccharide, and conjugate vaccines.
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What is the 6 needle injection?

The 6-in-1 vaccine used in the UK gives protection against these six serious diseases: diphtheria, tetanus, whooping cough (pertussis), polio, Hib disease (Haemophilus influenzae type b) and hepatitis B.
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Why did BCG leave a scar?

The BCG vaccine contains live attenuated Mycobacterium bovis and following intradermal injection the BCG vaccine elicits a local immune response. This response most often results in an ulcer that heals over weeks and leaves a flat permanent scar at the injection site [2].
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Why is BCG not given anymore?

However, BCG is not generally recommended for use in the United States because of the low risk of infection with Mycobacterium tuberculosis, the variable effectiveness of the vaccine against adult pulmonary TB, and the vaccine's potential interference with tuberculin skin test reactivity.
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Which disease has no cure?

dementia, including Alzheimer's disease, advanced lung, heart, kidney and liver disease, stroke and other neurological diseases, including motor neurone disease and multiple sclerosis.
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What diseases no longer exist?

Eradicated diseases
  • So far, only two diseases have been successfully eradicated—one specifically affecting humans (smallpox), and one affecting a wide range of ruminants (rinderpest).
  • Smallpox is the first disease, and so far the only infectious disease of humans, to be eradicated by deliberate intervention.
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Can smallpox come back?

Because smallpox no longer occurs naturally, scientists are only concerned that it could reemerge through bioterrorism.
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