What is Kleine Levin Syndrome?

Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male). It is characterized by recurring but reversible periods of excessive sleep
excessive sleep
Hypersomnia, defined as excessive daytime sleepiness (EDS) and/or total sleep time, commonly occurs in patients with mood disorders and is associated with treatment resistance, symptomatic relapse, increased risk of suicide, and functional impairment [2–7].
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC4526256
(up to 20 hours per day).
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What triggers Kleine-Levin syndrome?

The exact cause of Kleine-Levin syndrome is unknown. It is speculated that symptoms may develop due to malfunction or damage to the portion of the brain that helps to regulate functions such as sleep, appetite, and body temperature (hypothalamus).
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What triggers a KLS episode?

For example, KLS may arise from an injury in the hypothalamus, the part of the brain that controls sleep, appetite, and body temperature. A possible injury could be falling and hitting your head, although more research is needed to confirm this link. Some people develop KLS after an infection like the flu.
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How do you treat Kleine-Levin?

Treating Kleine-Levin Syndrome

There is no specific, definitive treatment to cure or control KLS. Some aspects of the disease can be managed with medication, such as stimulants to combat the EDS, but this is most effective only once the episodes have already decreased in severity.
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How do you know if you have KLS?

To be diagnosed with KLS, a person must meet first the criteria for recurrent hypersomnia: Episodes of excessive sleepiness lasting between two days and five weeks. Episodes occur at least once every 18 months and often more frequently. Normal behavior and cognition between episodes.
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Kleine-Levin Syndrome: Palm Beach Gardens teen has rare disorder that makes him sleep for weeks



How many people are affected by Kleine-Levin syndrome?

Kleine-Levin syndrome (KLS) is a rare disorder with an estimated prevalence of one to five cases per million population [2-8]. Patients with primary KLS can be found worldwide, with a higher prevalence among Ashkenazi Jews.
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How long do KLS episodes last?

While KLS episodes are most closely associated with large amounts of sleep, they can also bring about specific behavioral changes, increased hunger, and hypersexuality. Each episode can last a minimum of a week and a maximum of two months.
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How common is sleeping beauty syndrome?

Scientists estimate that the syndrome manifests in 1 to 5 people out of every million, according to the clinical resource UpToDate. Historically, more than 500 cases of the condition have been reported in the medical literature, although the unusual syndrome likely goes underdiagnosed.
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What are the 5 types of sleep disorders?

Thankfully, there are treatments available that you can talk to your patients about for the five most common sleep disorders:
  • Insomnia.
  • Sleep Apnea.
  • Narcolepsy.
  • Restless Legs Syndrome.
  • and REM Sleep Behavior Disorder.
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What does it mean when you sleep for days at a time?

Idiopathic hypersomnia – this sleep disorder is characterised by excessive night-time sleeping and the need for naps during the day. Unlike narcolepsy, it doesn't include cataplexy or sleep paralysis.
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What is the number one sleep disorder?

Insomnia - being unable to fall asleep and stay asleep. This is the most common sleep disorder.
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Why do I only sleep 4 hours a night?

If you cannot sleep for more than a few hours per night, you may have sleep deprivation. In addition, regular sleep interruptions from things like night terrors or "sleep starts" can also lead to sleep deprivation. If you have trouble falling asleep or staying asleep, your sleep deprivation may be caused by insomnia.
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Why do I wake up multiple times a night?

Most people wake up once or twice during the night. Reasons this might happen include drinking caffeine or alcohol late in the day, a poor sleep environment, a sleep disorder, or another health condition. When you can't get back to sleep quickly, you won't get enough quality sleep to keep you refreshed and healthy.
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What is the exploding head syndrome?

Exploding head syndrome (EHS) is a type of sleep disorder in which you hear a loud noise or explosive crashing sound in your head. The sound isn't real or heard by anyone else. The episode typically happens suddenly either when you're beginning to fall asleep or when you wake up during the night.
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Is Kleine-Levin syndrome genetic?

Kleine-Levin syndrome (KLS) is a rare periodic hypersomnia with associated behavioural abnormalities but with often favourable prognosis. There is excess risk of KLS in first-degree relatives, suggesting a strong genetic contribution.
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What organ is active at 4am?

The hours between 3am and 5am are governed by the lung meridian. Emotionally it is associated with grief and physically with the muscles around your lungs. The hours between 5am and 7am are governed by large intestine. Emotionally it is associated with being locked into a specific belief or way of thinking.
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Do you often wake up between 3 and 5 am a higher power is trying to tell you something?

But if you get up between 3 AM and 5 AM, then you should seriously consider that a sign that a higher power is trying to tell you something. when you wake up at this time during the night, you might pay closer attention as you could be getting an important message from the supernatural world.
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Why do I keep waking up at 3am?

People whose sleep is disrupted by waking up at 3 a.m. can try following healthy sleep tips to sleep through the night more consistently. Avoid caffeine and alcohol: Both caffeine and alcohol are associated with disrupted sleep, especially when they are consumed later in the day.
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Do short sleepers live longer?

Fu says researchers have found that short sleepers tend to be more optimistic, more energetic and better multitaskers. They also have a higher pain threshold, don't suffer from jet lag and some researchers believe they may even live longer.
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How Little sleep Can you survive on?

The longest recorded time without sleep is approximately 264 hours, or just over 11 consecutive days. Although it's unclear exactly how long humans can survive without sleep, it isn't long before the effects of sleep deprivation start to show. After only three or four nights without sleep, you can start to hallucinate.
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What is the best sleep aid?

What is the best sleep aid? While a lot of people might say melatonin is the best sleep aid, our experts actually point to lavender. Melatonin usually needs to be taken hours before sleep to help and really only helps if you have a clinical sleep issue.
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Why can't I sleep even though I'm tired?

If you're tired but can't sleep, it may be a sign that your circadian rhythm is off. However, being tired all day and awake at night can also be caused by poor napping habits, anxiety, depression, caffeine consumption, blue light from devices, sleep disorders, and even diet.
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How can I stay asleep all night?

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  1. Establish a quiet, relaxing bedtime routine. ...
  2. Relax your body. ...
  3. Make your bedroom conducive to sleep. ...
  4. Put clocks in your bedroom out of sight. ...
  5. Avoid caffeine after noon, and limit alcohol to 1 drink several hours before bedtime. ...
  6. Avoid smoking. ...
  7. Get regular exercise. ...
  8. Go to bed only when you're sleepy.
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How can I fall asleep in 10 seconds?

Relax your legs, thighs, and calves. Clear your mind for 10 seconds by imagining a relaxing scene. If this doesn't work, try saying the words “don't think” over and over for 10 seconds. Within 10 seconds, you should fall asleep!
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What is a person called who loves to sleep?

Clinophile is the word for those who love to sleep.
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