What is a Hemosiderotic dermatofibroma?

Abstract. A dermatofibroma (DF) is a common, benign tumor composed of fibroblastic and histiocytic cells. DF presents clinically with several different reported variants. One rare variant is hemosiderotic DF (HDF), which is made up of small blood vessels and hemosiderin
hemosiderin
Hemosiderin or haemosiderin is an iron-storage complex that is composed of partially digested ferritin and lysosomes. The breakdown of heme gives rise to biliverdin and iron. The body then traps the released iron and stores it as hemosiderin in tissues.
https://en.wikipedia.org › wiki › Hemosiderin
deposits
.
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Can dermatofibroma become cancerous?

However, if a person has a growth that looks like a dermatofibroma but is rapidly growing or changing, they should seek medical advice. This growth may be a sign of a rare type of cancer called dermatofibrosarcoma protuberans.
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What is dermatofibroma caused by?

Dermatofibromas are caused by an overgrowth of a mixture of different cell types in the dermis layer of the skin. The reasons why this overgrowth occurs aren't known. The growths often develop after some type of small trauma to the skin, including a puncture from a splinter or bug bite.
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Is dermatofibroma benign or malignant?

Dermatofibroma (cutaneous fibrous histiocytoma) represents a common benign mesenchymal tumor, and numerous morphological variants have been described. Some variants of dermatofibroma are characterized by an increased risk of local recurrences, and there are a few reported metastasizing cases.
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What does a dermatofibroma look like?

Cellular dermatofibromas look like small round or oval bumps. They're usually less than 1 centimeter (cm) in diameter. They may be flesh-colored, brown or reddish-brown. Usually, dermatofibromas form on your arms or legs.
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Cellular Dermatofibroma



Can you squeeze a dermatofibroma?

If you pinch a dermatofibroma, it creates a dimple because it is attached to the underlying subcutaneous tissue. 1 On the other hand, if you pinch a mole, it projects up away from the skin. Moles appear when skin cells grow in clusters.
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How do I get rid of dermatofibroma?

Symptomatic, protruding dermatofibromas can often be reduced in size by liquid nitrogen (freezing) therapy or steroid injections to the lesion. In patients with dark skin, freezing with liquid nitrogen and steroid injection of may cause pigmentary change that is usually temporary.
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Is dermatofibroma a cyst?

Dermatofibroma is a common benign mesenchymal skin tumor. Sweat duct cyst is an uncommon benign lesion containing squamous and glandular cells.
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Do dermatofibromas grow back?

If a dermatofibroma is not removed completely (for example if a shave removal clears the top of the lesion only) it will often grow back. Once the dermatofibroma is removed, the doctor will close the wound with stitches.
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Where do dermatofibromas occur?

Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma.
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Are dermatofibromas genetic?

Dermatofibromas are common among adults, more so in women. Their cause is probably genetic. Lesions are usually 0.5 to 1 cm in diameter, firm, and may dimple inward with gentle pinching. Most lesions are asymptomatic, but some itch or ulcerate after minor trauma.
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Do dermatofibromas appear suddenly?

There are specific situations where dermatofibromas can be associated with underlying health issues. Typically, multiple dermatofibroma lesions that arise suddenly are seen in these situations. If you have multiple skin lesions that have come on suddenly, you should discuss this with your physician.
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Is Dermatofibrosarcoma curable?

What is the prognosis for persons with DFSP? The general prognosis for DFSP is excellent. In the past, recurrence rates were high, but with the introduction of Mohs surgery, those rates have decreased. Even with recurrent DFSP, Mohs surgery has a 98% cure rate.
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How is Dermatofibrosarcoma treated?

Dermatofibrosarcoma protuberans treatment typically involves surgery to remove the cancer. Other treatments may be used to kill cancer cells that might remain after surgery.
...
Treatment options may include:
  1. Surgery to remove the cancer. ...
  2. Mohs surgery. ...
  3. Radiation therapy. ...
  4. Targeted therapy. ...
  5. Clinical trials.
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How much is it to remove dermatofibroma?

The Cost of Dermatofibroma Removal Procedure

Minor procedures at The Plastic Surgery Clinic range anywhere from $275-$350 depending on the complexity of your procedure.
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Do dermatofibromas get bigger?

Dermatofibromas are usually painless, but some people experience tenderness or itching. Most often, a single nodule develops, but some people can develop many dermatofibromas. They rarely grow larger than a half-inch in diameter. The cause of dermatofibromas is unknown.
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Does dermatofibroma cause pain?

Dermatofibromas are usually asymptomatic, but itching and pain often are noted. They are the most common of all painful skin tumors. Women who shave their legs may be bothered by the razor traumatizing the lesion in that region, causing pain, bleeding, erosive changes, and ulceration.
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Can you freeze off a dermatofibroma?

Benign skin lesions that are suitable for freezing include actinic keratosis, solar lentigo, seborrheic keratosis, viral wart, molluscum contagiosum, and dermatofibroma.
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Can you laser off dermatofibroma?

Dermatofibroma (DF), a common benign skin tumour, sometimes requires treatment either because of cosmetic concern or for associated symptoms. However, no effective treatment with optimal cosmetic outcomes has been reported. An effective and safe therapeutic option could be treatment with pulsed dye laser (PDL).
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Is Dermatofibrosarcoma malignant?

Dermatofibrosarcoma protuberans (DFSP) is a rare dermal malignancy affecting the deep dermis and subcutaneous tissues. It was first reported by Darier and Ferrand in 1924. This tumor is locally aggressive with high recurrence rates, but rarely metastasizes.
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Who treats Dermatofibrosarcoma?

Dermatologists also are studying new treatment options. One way to reduce DFSP from returning may be to treat patients with both excision and Mohs surgery.
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Can dermatofibroma turn into DFSP?

One year later, Hoffman (2) described the tendency of the dermatofibroma tumor to develop into protruding nodules and termed the condition dermatofibrosarcoma protuberans (DFSP).
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Can Dermatofibrosarcoma spread?

In dermatofibrosarcoma protuberans, the tumor has a tendency to return after being removed. However, it does not often spread to other parts of the body (metastasize ).
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Are dermatofibromas common?

Dermatofibroma (superficial benign fibrous histiocytoma) is a common cutaneous nodule of unknown etiology that occurs more often in women. Dermatofibroma frequently develops on the extremities (mostly the lower legs) and is usually asymptomatic, although pruritus and tenderness can be present.
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Is dermatofibroma safe?

Dermatofibromas are diagnosed by their appearance to the naked eye. The diagnosis may also be confirmed by removing and examining it under a microscope. Dermatofibromas do not go away by themselves. However, as they are harmless and do not turn into cancer, no treatment is usually needed.
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