Is HRT better than antidepressants?

Conclusions: The data suggest that antidepressant and antianxiety medications are more helpful than HRT in relieving peri- and postmenopausal depression or anxiety. However, most women managed the mood changes associated with menopause without psychopharmacologic intervention.
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Is HRT safer than antidepressants?

Depressive and anxiety symptoms also improved with HRT, which is safer and more effective than antidepressants.
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Does HRT help with depression?

If you're experiencing depression symptoms during menopause, HRT may be able to help. Estrogen injections may help increase the serotonin in your body, which may help boost your mood and reduce your risk for depression. If you're feeling depressed during menopause, treatments are available!
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Does HRT lift your mood?

Taking the right type of oestrogen can really help improve this low mood and other symptoms related to the menopause. Many women find that they feel calmer, have more energy, are more motivated and generally much happier when they take HRT.
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Can you take antidepressants and HRT at the same time?

In most cases, it's okay to take birth control pills or hormone replacement therapy (also called HRT) at the same time as depression medicines. Taking hormones may even help some depressed women feel better.
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HRT vs Antidepressants in Perimenopausal Depression by Prof Jayashri Kulkarni



Does HRT stop anxiety?

HRT with Estrogen May Lower Fear Response & Anxiety

They found that estrogen may have a calming effect on the fear response, including for women suffering from post-traumatic stress disorder (PTSD). Therefore, there is some evidence that increasing estrogen may reduce anxiety-like symptoms.
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Can HRT make anxiety worse?

There is evidence that some women experience unpleasant mood symptoms (such as irritability, depressed mood and anxiety) while receiving hormone replacement therapy (HRT) while taking the progestin / progesterone component of the HRT.
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Can lack of estrogen cause depression?

Depression: Estrogen is thought to increase serotonin, which is a chemical in the brain that boosts mood. Estrogen deficiency may cause a decline in serotonin that contributes to mood swings or depression.
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Can HRT make you feel worse at first?

Estrogen can give side effects of headache, breast tenderness and mild nausea. These tend to be common when you first start hormone replacement or increase the dose but often settle after a few weeks.
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How long does HRT take to improve mood?

It may take a few weeks to feel the effects of treatment and there may be some side effects at first. A GP will usually recommend trying treatment for 3 months to see if it helps. If it does not, they may suggest changing your dose, or changing the type of HRT you're taking.
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What does HRT do to you mentally?

While gender affirming hormone therapy usually results in an improvement in mood, some people may experience mood swings or a worsening of anxiety, depression, or other mental health conditions as a result of the shifts associated with starting a second puberty.
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How will HRT make me feel?

Some women who use HRT say they feel bloated or have breast soreness. Nausea, dizziness, headaches, and blurry vision are also possible side effects, as is vaginal bleeding.
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What are the benefits of taking HRT?

Benefits of HRT include:
  • Reduction in vasomotor symptoms.
  • Improvement in quality of life. ...
  • Improvement in mood changes.
  • Improvement of urogenital symptoms.
  • Reduction in osteoporosis risk.
  • Reduction in cardiovascular disease.
  • Lower risk of colorectal cancer.
  • Other benefits.
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Can antidepressants make menopause worse?

Women going through the menopause are being wrongly prescribed antidepressants which are making their symptoms worse and destroying their confidence, experts have warned. New research has found over a third of women going to their GP with symptoms of the menopause are being offered antidepressants.
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Does HRT cause weight gain?

Many women believe that taking HRT will make them put on weight, but there's no evidence to support this claim. You may gain some weight during the menopause, but this often happens regardless of whether you take HRT. Exercising regularly and eating a healthy diet should help you to lose any unwanted weight.
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How do you know if HRT is right for me?

Your family history and your personal medical history and risk of cancer, heart disease, stroke, blood clots, liver disease and osteoporosis are important factors in determining whether hormone replacement therapy is appropriate for you.
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Why do I feel awful on HRT?

When starting HRT, it's very common to experience some initial side effects or start-up symptoms such as breast tenderness or breast size increase. Some women describe slight nausea, headaches or abdominal bloating. Light erratic bleeding is also quite usual.
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Will I lose weight on HRT?

Many women actually find that they lose weight by using HRT as it shifts the metabolism back into a pre-menopausal metabolic state. Progesterone can sometimes cause fluid retention which can mimic weight gain, but there are alterations that can be made to the regime to minimise this impact.
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Does HRT make you look younger?

One of the benefits of hormone replacement therapy is that it can make you look younger. Hormone replacement therapy, or more specifically estrogen, can help reduce the appearance of fine lines and wrinkles on the skin. It can also promote hair growth, which can contribute to a more youthful appearance.
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What does low estrogen feel like?

Low estrogen can affect your body in various ways, depending on where you are in terms of your sexual development. Low estrogen: May delay puberty, slow or prevent sexual development. Occurs in perimenopause and menopause, often leading to painful sex, lower sexual desire and hot flashes.
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What is the best HRT for anxiety?

Conclusion: HRT with 17beta-estradiol and tibolone improves symptoms of anxiety and depression in menopausal women.
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What are the signs of low estrogen?

Common symptoms of low estrogen include:
  • painful sex due to a lack of vaginal lubrication.
  • an increase in urinary tract infection (UTIs) due to a thinning of the urethra.
  • irregular or absent periods.
  • shifts in mood.
  • hot flashes.
  • breast tenderness.
  • headaches or accentuation of pre-existing migraines.
  • depression.
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Does HRT help with sleep?

Hormone replacement therapy (HRT)

Systemic HRT can improve sleep quality, making it easier to get off to sleep, with less night-time waking; it has also been shown to improve chronic pain, mood and genitourinary symptoms.
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What is the best antidepressant for menopause?

SSRIs – The selective serotonin receptor inhibitors (SSRIs) are the class of antidepressants used most commonly for treating hot flashes. A form of paroxetine (sample brand name: Brisdelle) is an SSRI and is the only nonhormonal therapy that is specifically approved for hot flashes in the United States.
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Does HRT help with brain fog?

Fortunately, the right type and dose of hormone replacement therapy (HRT) (with testosterone for those who need it) can improve brain fog and help you think more clearly.
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