Is B12 level of 1500 too high?

Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10. Excess B12 is either stored in the liver, present in the blood without any adverse effects, or excreted.
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What is a dangerously high B12 level?

An abnormally high vitamin B-12 status is anything over 900 pg/mL. This result may suggest liver or kidney problems, diabetes, or certain forms of leukemia.
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What does a B12 of 1500 mean?

Understanding the Results

But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.
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Is B12 level of 1200 too high?

Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity.
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What causes very high levels of B12?

Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)
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Is Too Much B12 Bad (Can You Take Too Much b12?)



Why is my B12 over 2000?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don't worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.
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What cancers cause high B12?

Other studies focusing on specific cancers have shown a strong association between elevated B12 levels and liver cancers (OR 3.3 [95%CI: 1.1–10.4] for hepatocellular carcinomas and OR 4.7 [95%CI: 1.2–17.9] for other liver cancers) [16], a moderate association with prostate cancer (OR 1.1 [95%CI: 1.0–1.2]) [17], and no ...
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How long does it take to get rid of excess B12?

If a person stops consuming the vitamin, the body's stores of this vitamin usually take about 3 to 5 years to exhaust. People should not take high doses of vitamin B12 as a cure-all, but otherwise the vitamin does not appear to be toxic; consuming excess amounts of B12 is not recommended.
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What if B12 is more than 1000?

The association between elevated B12 and solid cancers was demonstrated by two population-based studies: a B12 > 800 pmol/L (1084 ng/L) was associated with a diagnosis of cancer in the following year with a Standardized Incidence Ratio of 6.3 [95% CI 5.7–6.9] in a Danish cohort16, and a B12 between 800 and 1000 pmol/L ...
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Can you overdose on vitamin B12?

No, you cannot overdose on B12

Vitamin B12 is a water-soluble vitamin, meaning it dissolves in water and is quickly absorbed by the body. It is stored in the liver and whatever your body doesn't use is excreted through urine, Allen says. Even in high doses, your body can only absorb a fraction of B12 supplements.
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How do I lower my vitamin B12?

Research has suggested that the consumption of alcohol may reduce vitamin B12 levels. An older study indicated that moderate alcohol intake diminished vitamin B12 by 5% among “healthy, well-nourished, postmenopausal women.” Alcohol-related liver disease may falsely increase vitamin B12 test levels.
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Is B12 a tumor marker?

Elevated Plasma Vitamin B12 Levels as a Marker for Cancer: A Population-Based Cohort Study. Affiliations of authors:Department of Clinical Epidemiology (JFBA, LP, HTS) and Department of Clinical Biochemistry (JFBA, EN), Aarhus University Hospital, Aarhus, Denmark. Corresponding author.
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Can autoimmune cause high B12?

Abnormally elevated B12 has been attributed many causes [5,6], e.g., myeloid blood malignancies [7,8,9], acute or chronic liver diseases [10,11,12], chronic kidney failure, autoimmune or inflammatory diseases [3], and Gaucher disease [13].
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Can B12 be falsely elevated?

Some studies have indicated that elevated serum levels of vitamin B12 might be a sign of a serious and life-threatening disease. Such falsely high valued of serum vitamin B12 levels are observed in myeloproliferative disease, acute hepatitis, severe alcoholic liver disease, and cirrhosis.
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Do Diabetics have high B12 levels?

Increasing duration of diabetes was associated with higher serum Vitamin B12 levels.
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Can fatty liver cause high B12 levels?

Six out of eight showed a higher B12 level in NAFLD patients (mean 223.5 to 473.1 pg/mL) when compared to controls (mean 171.9 to 448.0 pg/mL). Seven out of eight studies presented higher HCY levels in NAFLD patients (mean 9.18 to 56.3 umol/L) when compared to controls (mean 8.49 to 19.7 umol/L).
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Can Rheumatoid arthritis cause high B12?

Serum B12 level in patients with rheumatoid arthritis was significantly higher than that in patients with osteoarthritis and normal subjects.
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Is 1000mcg too much B12?

High doses of B vitamins over 1,000 mcg have also been associated with complications in people with kidney disease ( 22 ). Furthermore, extremely high blood levels of B12 in mothers was connected to a higher risk of autism in their children ( 23 ).
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Can too much B12 cause tingling?

Tingling sensation or Numbness

In some patients, tingling sensation is experienced mostly in the right side of the body. This symptom is one of the early warning indicators of Vitamin B12 overdose.
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What is normal level of vitamin B12 in elderly?

A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly.
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Can too much vitamin B hurt you?

Safety and side effects

Consuming vitamin B-6 through food appears to be safe, even in excessive amounts. When used as a supplement in appropriate doses, vitamin B-6 is likely safe. However, taking too much vitamin B-6 from supplements can cause: A lack of muscle control or coordination of voluntary movements (ataxia)
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Does vitamin B12 cause weight gain?

Despite the numerous processes in which vitamin B12 is involved, there's little evidence to suggest that it has any influence on weight gain or loss.
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What are the side effects of B12 1000 mcg?

Check with your doctor or nurse immediately if any of the following side effects occur while taking cyanocobalamin:
  • Abdominal or stomach pain.
  • bleeding from the gums or nose.
  • blue lips and fingernails.
  • chest pain.
  • coughing that sometimes produces a pink frothy sputum.
  • decreased urine output.
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Can anemia cause high B12 levels?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.
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Can too much B12 damage your liver?

Vitamin B12 therapy has not been linked to ALT elevations or to clinically apparent acute liver injury. Likelihood score: E (unlikely cause of liver injury).
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