How serious is endometrial hyperplasia?

Untreated atypical endometrial hyperplasia can become cancerous. Endometrial or uterine cancer develops in about 8% of women with untreated simple atypical endometrial hyperplasia. Close to 30% of women with complex atypical endometrial hyperplasia who don't get treatment develop cancer.

How long does it take for endometrial hyperplasia to turn into cancer?

In one study, hyperplasia without atypia progressed to endometrial carcinoma in fewer than 5% of women; in comparison, atypical hyperplasia progressed to endometrial carcinoma in one in eight women within 10 years, and in one in three women within 20 years.

Is endometrial hyperplasia life threatening?

If left untreated, atypical endometrial hyperplasia can become cancerous. About 8% of women with simple atypical endometrial hyperplasia who don't get treatment develop cancer. Nearly 30% of those with untreated complex atypical endometrial hyperplasia develop cancer.

Is endometrial hyperplasia curable?

In most cases, endometrial hyperplasia is very treatable. Work with your doctor to create a treatment plan. If you have a severe type or if the condition is ongoing, you might need to see your doctor more often to monitor any changes.

What percentage of endometrial hyperplasia is cancer?

Endometrial hyperplasia

If the hyperplasia is called “atypical,” it has a higher chance of becoming a cancer. Simple atypical hyperplasia turns into cancer in about 8% of cases if it's not treated.

Endometrial hyperplasia - an Osmosis Preview

What are the warning signs of uterine cancer?

What were your first signs of uterine cancer?

What is the best treatment for endometrial hyperplasia?

In many cases, endometrial hyperplasia can be treated with progestin. Progestin is given orally, in a shot, in an intrauterine device (IUD), or as a vaginal cream. How much and how long you take it depends on your age and the type of hyperplasia. Treatment with progestin may cause vaginal bleeding like a period.

When should I worry about endometrial thickness?

If an endometrial thickness of ≥ 8 mm is considered abnormal, 0.9% of women without cancer and without bleeding and 12% of women without cancer and with bleeding will have endometrial measurements above this threshold, and 95% of women with cancer will have endometrial measurements above this threshold.

What is the most common age to get endometrial hyperplasia?

In our study, among women 18–90 years the overall incidence of endometrial hyperplasia was 133 per 100,000 woman-years, was most common in women ages 50–54, and was rarely observed in women under 30. Simple and complex hyperplasia incidences peaked in women ages 50–54.

What happens if your endometrial biopsy is positive?

Biopsy results may show cell changes linked to hormone levels, or abnormal tissues, such as fibroids or polyps. These can lead to abnormal bleeding. Your provider can also use endometrial biopsy to check for uterine infections, such as endometritis.

Is endometrial hyperplasia painful?

Some of the most common symptoms of endometrial hyperplasia include: Abnormal vaginal bleeding between menstrual periods or post-menopause. Abnormally heavy menstrual bleeding. Painful intercourse.

What is the most common cause of endometrial thickening?

The most common cause of endometrial hyperplasia is having too much estrogen and not enough progesterone. That leads to cell overgrowth. There are several reasons you might have a hormonal imbalance: You've reached menopause.

Is a thick uterine lining always cancer?

Thickened womb lining

Endometrial hyperplasia is a non cancerous (benign) condition where the lining of the womb becomes thicker. You have a higher risk of developing womb cancer if you have this thickening, especially if the extra lining cells are abnormal.

Should I get a hysterectomy if I have precancerous cells?

If the precancerous disease is more extensive or involves adenocarcinoma in situ (AIS), and the woman has completed childbearing, a total hysterectomy may be recommended. 1 During a total hysterectomy, the entire uterus (including the cervix) is removed.

Does hyperplasia mean cancer?

An increase in the number of cells in an organ or tissue. These cells appear normal under a microscope. They are not cancer, but may become cancer.

How painful is endometrial biopsy?

Most people have mild to moderate cramping. Some women have severe cramping during the procedure. The cramping will lessen shortly after the biopsy is finished. You can get pain medicine if you need.

How long does it take to get results from an endometrial biopsy?

The sample of tissue is put in fluid and sent to a laboratory for analysis. Your doctor should have the results approximately 7 to 10 days after the biopsy. You may experience some light spotting or bleeding after the procedure, so you'll be given a menstruation pad to wear. Mild cramping is also normal.

What happens if endometrial thickness is 20mm?

Transvaginal ultrasound showing thickened endometrial stripe is supportive of the diagnosis, with thickness approaching or exceeding 20mm being highly suggestive of malignancy, and less than 4mm being supportive of benign causes.

How do you get rid of endometrial hyperplasia naturally?

Can endometrial hyperplasia be reversed?

Based on four large series, more than 90% of endometrial hyperplasia caused by ERT can be reversed by medical treatment.

Can endometrial thickness be reduced?

Medical Treatments

Hormones may be used to moderate the thickness of the endometrial lining. Progesterone may be used in hyperplasia to decrease endometrial thickness. Estrogen may be used to thicken the endometrial lining of if it is too thin.

How do you feel when you have endometrial cancer?

Early symptoms include unusual bleeding, such as after menopause or between periods. Endometrial cancer can also cause pain in the pelvic area, less commonly during sexual intercourse. Some people also experience pain when urinating or difficulty emptying the bladder.

Can endometrial cancer be seen on ultrasound?

For Endometrial Cancer, Ultrasound is the Key to Early Detection. With endometrial cancer ultrasound, physicians are able to evaluate results and reach a diagnosis with speed and confidence.

Should I be worried about endometrial cancer?

Uterine cancer, also known as endometrial cancer, is the most common gynecologic cancer in the United States The good news is that if it's caught early, it's highly treatable. Don't ignore the signs. The most important thing you can do is to know the warning signs and bring them to your doctor's attention.