How common is twin to twin syndrome?

Twin-twin transfusion syndrome affects approximately 5 to 15 percent of identical twin pregnancies, meaning that approximately 6,000 babies may be affected each year.
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Can twins survive TTTS?

The majority of TTTS twins who have appropriate treatment during pregnancy will survive and the majority of survivors will be normal and healthy. If untreated, the survival rate for TTTS twins is approximately 10 to 15 percent. Once TTTS babies are born, blood supply sharing is no longer a factor.
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How do you avoid twin to twin transfusions?

The exact cause of TTTS is not well understood; there are no known genetic causes of TTTS, and there's nothing a mother did to cause it. In the majority of cases, TTTS develops in the second trimester of pregnancy. While there's nothing anyone can do to prevent TTTS, there's plenty we can do to help your babies.
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What is the most common procedure to treat twin to twin syndrome?

In complicated cases of twin-to-twin transfusion syndrome (TTTS), minimally invasive surgery can offer the best chance of having two healthy babies. This surgery, known as endoscopic laser ablation, is performed in utero and can correct the blood-sharing imbalance caused by TTTS.
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What are the symptoms of twin-to-twin transfusion syndrome?

What are the Warning Signs of TTTS?
  • The sensation of a rapid growth of the womb.
  • A uterus that measures large for dates.
  • Abdominal pain or tightness, or uterine contractions.
  • Sudden increases in body weight.
  • Hand and leg swelling in early pregnancy.
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Twin To Twin Transfusion Syndrome | Q



When does twin-to-twin transfusion syndrome happen?

Twin-to-twin transfusion syndrome typically develops between weeks 16 and 26 of a woman's pregnancy. But an ultrasound as early as 10 to 14 weeks can put doctors on alert that there is a twin gestation, and if they are sharing a placenta. TTTS is diagnosed by measuring levels of amniotic fluid.
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How quickly does TTTS progress?

Results: Among 132 consecutive cases of TTTS, 46 women presented with Stage I disease. In the majority (69.6%), disease remained stable (28.3%) or regressed (41.3%). Of cases that progressed, 79% did so within 2 weeks and 93% progressed to at least Stage III.
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What is a daisy baby?

All babies affected by TTTS, including TAPS, SIUGR and TRAP are called Daisy Babies.
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How does the death of a twin affect the other twin?

Twins literally do not know how to exist as one. When a twin dies, the twinless twin longs to reconnect. The twinless twin may have phantom pain or feel half dead. He or she may feel a need to represent both him or herself and the deceased twin or may even take on behaviors of the deceased twin.
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Can non identical twins have TTTS?

Although all identical twins share a placenta, TTTS develops in about 10 to 15 percent of those pregnancies. The condition does not occur when the twins are non-identical (fraternal).
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Which parent carries twin gene?

The gene versions that increase the chance of hyperovulation can be passed down from parent to child. This is why fraternal twins run in families. However, only women ovulate. So, the mother's genes control this and the fathers don't.
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How early can TTTS be treated?

There are a few options to treat TTTS before birth, but only the most severe cases should be treated with fetal intervention. Observation, with or without bed rest. If TTTS occurs in the third trimester, conservative measures and early delivery are usually recommended.
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Can TTTS stay at Stage 1?

Among 132 consecutive cases of TTTS, 46 women presented with Stage I disease. In the majority (69.6%), disease remained stable (28.3%) or regressed (41.3%).
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Why does twin-to-twin transfusion happen?

Unequal sharing of blood flow can cause TTTS. It most often develops in the second trimester of pregnancy but can happen at any point. When babies are diagnosed with twin-to-twin transfusion syndrome, the baby sending more blood to the other will make less urine and have less fluid around them (oligohydramnios).
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What is a twinless twin called?

A twinless twin, or lone twin, is a person whose twin has died. Twinless twins around the world unite through organizations and online groups to share support and the status as a twinless twin. Triplets, quadruplets and higher order multiples can also experience this sort of loss.
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Can twins fight in womb?

Just like singleton babies, twins can sometimes get super-active in the womb. But not to worry — there's no real threat from it! Babies can kick or even hit each other (yes, really) in utero, but the good news is the amniotic fluid acts as a cushion to protect them from actually getting hurt by any of it.
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What do you say when one twin dies at birth?

simplest expression of sorrow is best, plus appreciation of the surviving baby as you do not want to detract from that. A donation to a neonatal charity would be appreciated I am sure and a present for the baby. It would be so sad if the joy at his/her birth were always to be overshadowed by the loss of the twin.
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What is Stage 3 twin-to-twin transfusion syndrome?

Stage 3: The imbalance of blood flow starts to affect the heart function in one or both babies. This is seen in abnormal blood flow in the umbilical cords or hearts of the twins.
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What happens when one twin is bigger than the other?

In roughly 30 percent all twin births, one baby will be larger than the other. Some studies suggest that if one of your babies is at least 25 percent heavier than the other, one or both of them may be more likely to have breathing problems or need intensive care.
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How is twin to twin transfusion treated?

Twin-twin transfusion syndrome can be treated with fetal laser photocoagulation (FLP), which selectively and sequentially ablates connections, depending on the type, to prevent the loss of one or both fetuses.
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Can TTTS regress?

Most cases of TTTS present in the early second trimester and are staged according to the system shown in the table (table 1), formerly called the Quintero classification system. The stage may remain stable, regress, or progress over time, and progression can occur rapidly.
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What is the survival rate of identical twins?

The survival of monochorionic twins diagnosed in the first trimester is 89%. Twin-to-twin transfusion syndrome (TTTS) occurs in 9% and is the most important cause of death.
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What is the difference between TTTS and TAPS?

TTTS and TAPS are both chronic forms of feto-fetal transfusion. TTTS is characterized by the twin oligo-polyhydramnios sequence (TOPS), whereas TAPS is characterized by large inter-twin hemoglobin differences in the absence of amniotic fluid discordances.
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What happens when one twin dies in the second trimester?

If the twin dies in the second or third trimester, there are increased risks to the surviving fetus, including a higher rate of cerebral palsy. When a twin dies after the embryonic period of gestation, the water within the twin's tissues, the amniotic fluid, and the placental tissue may be reabsorbed.
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What are the stages of TTS?

Quintero TTTS Staging System
  • Stage I: The fetal bladder of the donor twin remains visible on ultrasound.
  • Stage II: The bladder of the donor twin is not visible on ultrasound.
  • Stage III: Doppler studies in either twin are critically abnormal fetal. ...
  • Stage IV: Fetal hydrops is noted.
  • Stage V: Demise of one or both twins.
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