Does clopidogrel affect sleep?

The organic nitrates (isosorbide) and the antiplatelet agents (acetylsalicylic acid, clopidogrel) are among the most prescribed drugs in cardiology and are not cited as causing insomnia or sleepiness.
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Is insomnia a side effect of blood thinners?

Abstract. Purpose: Insomnia is an important adverse event of mechanical thromboprophylaxis. This sleep disorder has been reported as one of the commonest adverse events of the new oral anti-Xa anticoagulant darexaban, with similar rates to mechanical thromboprophylaxis in a randomized controlled trial (RCT).
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Do statins keep you awake at night?

How they can cause insomnia: The most common side effect of all types of statins is muscle pain, which can keep people who take them awake at night and unable to rest. In the worst cases, the pain caused by statins can be immobilizing.
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Can clopidogrel cause anxiety?

headache, fever, weakness, feeling tired; little or no urination; a seizure; low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or.
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What medication causes sleeplessness?

Medications that can cause insomnia include:
  • Selective serotonin reuptake inhibitors (antidepressants such as Prozac® and Zoloft®)
  • Dopamine agonists (includes some medications for Parkinson's disease)
  • Psychostimulants and amphetamines.
  • Anticonvulsants.
  • Cold medicines and decongestants.
  • Steroids.
  • Beta agonists.
  • Theophylline.
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How Do Antidepressants Affect Sleep?



Why I Cannot sleep at night?

Common causes of chronic insomnia include: Stress. Concerns about work, school, health, finances or family can keep your mind active at night, making it difficult to sleep. Stressful life events or trauma — such as the death or illness of a loved one, divorce, or a job loss — also may lead to insomnia.
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Why can't I sleep even though I'm tired?

If you're tired but can't sleep, it may be a sign that your circadian rhythm is off. However, being tired all day and awake at night can also be caused by poor napping habits, anxiety, depression, caffeine consumption, blue light from devices, sleep disorders, and even diet.
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Does clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.
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What are the most common side effects of clopidogrel?

Common side effects

bleeding more easily than normal – nosebleeds, bruising more easily or bleeding that takes longer to stop. diarrhoea. stomach pain. indigestion or heartburn.
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What is the most serious adverse effect of clopidogrel?

Serious side effects

severe stomach ache or abdominal pain. uncontrolled bleeding or unusual bruising. vomiting with blood. weakness or numbness in an arm or leg.
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Can cholesterol tablets cause insomnia?

The current evidence, from well-run research trials of more than 100,000 patients, is that statins do not cause insomnia or any other sleep disturbance, compared with a dummy pill (placebo).
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Which statins must be taken at bedtime?

To maximize the effects of statins with a short half-life, fluvastatin, lovastatin, and simvastatin should be dosed at bedtime allowing the greatest drug concentration to be present during peak endogenous cholesterol synthesis.
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What medication keeps you awake?

Stimulants. If necessary, a GP or specialist may prescribe a type of medicine known as a stimulant, such as modafinil, dexamphetamine, methylphenidate or pitolisant. These medicines stimulate your central nervous system, which can help keep you awake during the day.
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Do blood thinners make you feel tired?

Aside from bleeding-related issues, there are several side effects that have been linked to blood thinners, such as nausea and low counts of cells in your blood. Low blood cell count can cause fatigue, weakness, dizziness and shortness of breath. Be careful mixing medications.
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How can I cure insomnia fast?

Basic tips:
  1. Stick to a sleep schedule. Keep your bedtime and wake time consistent from day to day, including on weekends.
  2. Stay active. ...
  3. Check your medications. ...
  4. Avoid or limit naps. ...
  5. Avoid or limit caffeine and alcohol and don't use nicotine. ...
  6. Don't put up with pain. ...
  7. Avoid large meals and beverages before bed.
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Do statins make you sleep better?

Conclusions. The results indicated that statins have no significant adverse effect on sleep duration and efficiency, entry to stage I, or latency to stage I sleep, but significantly reduce wake time and number of awakenings.
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Do the side effects of clopidogrel go away?

Some side effects of clopidogrel may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
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What should I monitor with clopidogrel?

HPR while on this drug is associated with major adverse cardiovascular events. The best assays to monitor clopidogrel therapy include VerifyNow and Multiplate ADP test.
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What should you not take with clopidogrel?

Clopidogrel may interact with other medications
  • Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
  • Stomach acid drugs (proton pump inhibitors) ...
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
  • Blood thinners.
  • Drugs used to treat depression. ...
  • Salicylates (aspirin) ...
  • Opioids.
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How do you know if clopidogrel is working?

Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.
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How long can you stay on clopidogrel?

The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.
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Does clopidogrel affect blood pressure?

You likely won't have blood pressure changes while you're taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.
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How can I fall asleep and stay asleep?

Advertisement
  1. Establish a quiet, relaxing bedtime routine. ...
  2. Relax your body. ...
  3. Make your bedroom conducive to sleep. ...
  4. Put clocks in your bedroom out of sight. ...
  5. Avoid caffeine after noon, and limit alcohol to 1 drink several hours before bedtime. ...
  6. Avoid smoking. ...
  7. Get regular exercise. ...
  8. Go to bed only when you're sleepy.
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Why do I keep waking up at night?

Stress is one of the main reasons people wake up in the night. It makes your sleep lighter and keeps you from getting deep and REM sleep. Other mental health problems can also cause sleep problems, including: Anxiety disorders such as post-traumatic stress disorder (PTSD)
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How can I sleep better at night naturally?

Five tips for better sleep
  1. Drink up. No, not alcohol, which can interfere with sleep. ...
  2. Exercise . Physical activity can improve sleep, though researchers aren't completely sure why. ...
  3. Use melatonin supplements . ...
  4. Keep cool. ...
  5. Go dark.
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