Can MS lesions shrink?

Lesion accrual in multiple sclerosis (MS) is an important and clinically relevant measure, used extensively as an imaging trial endpoint. However, lesions may also shrink or disappear entirely due to atrophy.
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Do MS lesions disappear?

Conclusions: Brainstem lesions in MS patients can disappear on subsequent imaging. Disappearing MRI lesions may delay the diagnosis. These results suggest that more weight should be given to the reported clinical brainstem events, especially in the initial diagnosis of MS.
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Can MS lesions improve?

Can Lesions Heal Once They Appear? “Absolutely,” says Dr. Hua. “It's not specific to MS, but in any process where there's some sort of brain injury, there will always be healing, as well.
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Can you reverse MS lesions?

Study takes research into area of reversing myelin damage

There is currently no cure for MS, although some approved drugs appear to reduce frequency of relapses and delay disease progression to some extent.
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Do MS lesions repair themselves?

With regular scans, a neurologist can tell how active your MS is, and to what extent your nerves are being damaged. Sometimes, lesions will repair themselves and not be seen on subsequent scans. Persistent lesions may eventually show up as 'black holes', where the underlying neuron has suffered irrepairable damage.
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Types of MS Lesions - National MS Society



How long does it take MS lesions to heal?

The brightness represents an area of swelling (e.g. increased fluid) as the region becomes inflamed. The excess fluid is slowly reabsorbed, so that enhancing lesions typically disappear within 3-4 weeks.
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How long are MS lesions active?

Most symptoms develop abruptly, within hours or days. These attacks or relapses of MS typically reach their peak within a few days at most and then resolve slowly over the next several days or weeks so that a typical relapse will be symptomatic for about eight weeks from onset to recovery.
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Can myelin sheath repair itself?

The human body has an amazing natural ability to repair myelin and get nerves working properly again. Myelin is repaired or replaced by special cells in the brain called oligodendrocytes. These cells are made from a type of stem cell found in the brain, called oligodendrocyte precursor cells (OPCs).
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Can vitamin D help MS symptoms?

Research over the years has shown that maintaining adequate levels of vitamin D may have a protective effect and lower the risk of developing multiple sclerosis (MS). A number of studies have shown that people who get more sun exposure and vitamin D in their diet have a lower risk of MS .
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Is MS reversible with diet?

( 4 ). Although diet cannot cure MS, some research suggests that making dietary changes may help people with MS better manage their symptoms. This, in turn, may improve their quality of life ( 5 , 6 ).
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Can MS stay mild?

After the first round of symptoms, multiple sclerosis can stay mild without causing major problems for decades, a 30-year British study indicates.
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Can you slow the progression of MS?

Multiple sclerosis (MS) is difficult to diagnose, and, as yet, it has no cure. However, according to new research, it may be possible to slow its progression without some of the health risks associated with current treatments.
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How do I know if my MS is progressing?

To figure out if disease is progressing, doctors use a scale called the Expanded Disability Status Scale (EDSS). The EDSS is a way of measuring physical disability. Two-thirds of those with MS will not progress past level 6 on the EDSS.
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Can MS come and go?

MS symptoms can come and go and change over time. They can be mild, or more severe. The symptoms of MS are caused by your immune system attacking the nerves in your brain or spinal cord by mistake. These nerves control lots of different parts of your body.
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Can B12 help MS?

You need vitamin B12 to help maintain your nerves' myelin sheath. If you are deficient in vitamin B12 you can get symptoms that are similar to some of the symptoms of MS, such as fatigue, weakness, numbness or tingling and problems with memory.
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Is Magnesium Good for MS?

Magnesium is often prescribed for nocturnal leg cramps or general muscle cramps, and some healthcare providers suggest it can be used to ease the muscle spasms of MS.
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How much vitamin D should I take if I have MS?

Vitamin D sources and supplements

Mattson tends to recommend 1,000 to 2,000 IU per day to people with MS, even if levels are normal, to boost the protective factor against MS activity. “If vitamin D levels are low, I tend to recommend 2,000 units per day.
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Can you reverse demyelination?

No cures exist for demyelinating diseases and their progression, and symptoms are different for everyone. Getting treatment early is important. Treatment focuses on: Minimizing the effects of the attacks.
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Does B12 repair myelin sheath?

These data suggested that vitamin B12 increased the level of MBP, which plays vital roles in the myelination process and the appropriate formation of myelin thickness and compactness. Meanwhile, LFB staining showed that vitamin B12 restored myelin by reducing the vacuolar changes in the myelin sheath after TBI.
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How close is a cure for MS?

After how long? Probably between 5-15 years. If cure means 'no more disease activity and no further treatment', this is likely to be achievable with the currently available high efficacy medications.
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How many lesions is alot for MS?

According to the team, patients with a combination of more than 13 lesions, with a maximal lesion diameter greater than 0.75 cm, and lesions perpendicular to the corpus callosum, had a 19 times greater chance of progressing to MS during the following year.
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Can MS symptoms get worse without new lesions?

After a certain amount of time, “You look and see that you're not having the same kind of relapses, there are no new MRI lesions, but there are certain symptoms that are gradually getting worse,” Shephard says of her gradual change to secondary-progressive MS.
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How long do MS flares last?

How long do they last? To qualify as a flare-up, symptoms must last for at least 24 hours. The duration of a flare-up can be different for each person and for each flare-up. Flare-ups may only last for a few days, but sometimes they can last for weeks and even months at a time.
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Do MS patients always have brain lesions?

About 5 percent of people who are confirmed to have MS do not initially have brain lesions evidenced by MRI. However, the longer a person goes without brain or spinal cord lesions on MRI, the more important it becomes to look for other possible diagnoses.
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Can MS get better?

MS is a chronic (long-term) condition. There's no cure, but effective treatments are available. Treatments for relapsing remitting MS can lengthen the time between relapses. They can also prevent or delay progression to another stage of MS.
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