Can bupropion cause weight gain?

Though most antidepressants can cause weight gain, bupropion is a medication for depression that can lead to weight loss. If people with depression are concerned about weight gain, this might be a suitable option. People who do not have depression should not take bupropion to lose weight.
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Is bupropion making me gain weight?

Official answer. Wellbutrin XL and Wellbutrin SR are different formulations of the antidepressant bupropion. Both Wellbutrin XL and Wellbutrin SR may cause weight gain or weight loss, but weight loss is more common. Not everyone taking these drugs will experience a change in weight.
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How fast do you lose weight on bupropion?

How long does it take for Wellbutrin to work for weight loss? In people who lose weight as a side effect of Wellbutrin, it is possible to notice weight changes within eight weeks.
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Which antidepressants cause the most weight gain?

Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.
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How do you lose weight on Wellbutrin?

Wellbutrin for Weight Loss Dosage
  1. Patients may be prescribed a starting dose of Contrave, which is one tablet (naltrexone 8 mg/bupropion 90 mg) once daily in the morning for 1 week.
  2. This dosage is then increased at week 2 to 1 tablet twice daily, administered in the morning and evening.
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Why do you gain weight with antidepressants and mood stabilizers?



Does Wellbutrin affect metabolism?

This increases the level of both chemicals in the brain (Huecker, 2020). Experts aren't exactly sure how bupropion works to stimulate weight loss. It may act on receptors and neurotransmitters in the brain that affect metabolism and appetite.
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Is Wellbutrin an appetite suppressant?

It stimulates noradrenaline, dopamine, and (less-so) serotonin receptors. This gives you more energy, suppresses your appetite, and enhances your mood.
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How can I avoid gaining weight on antidepressants?

As simple as it may sound, the best chance of avoiding, or lessening further, undesirable weight gain when taking a prescribed antidepressant or antipsychotic medication, is to simultaneously participate in a formal weight management program.
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What are the side effects of bupropion?

Bupropion may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • drowsiness.
  • anxiety.
  • excitement.
  • difficulty falling asleep or staying asleep.
  • dry mouth.
  • dizziness.
  • headache.
  • nausea.
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What is the best antidepressant for weight loss?

Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.
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How can I tell if Wellbutrin is working?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
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Does bupropion give you energy?

Conclusions: Our results demonstrated that bupropion increased some enzymes of brain energy metabolism. These findings are in accordance with other studies which showed that some antidepressants may improve energy metabolism.
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Does bupropion cause hair loss?

The antidepressant Wellbutrin (bupropion) can cause hair loss, also called alopecia. This side effect can occur with other other antidepressants as well.
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What happens when you stop taking bupropion?

Common withdrawal symptoms of Wellbutrin include irritability, dizziness, headaches, aggression, flu symptoms, anxiety, depression, sleep changes, nausea, cramps, tremors, suicidal thoughts, excessive sweating, trouble balancing and difficulty tolerating warm temperatures.
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Can I stop taking bupropion?

If you no longer want to take bupropion, it's important to talk to your healthcare provider first. If you abruptly stop taking bupropion without first talking to your healthcare provider, you may experience a condition called antidepressant discontinuation syndrome.
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Is 300 mg bupropion a lot?

Adults—At first, 150 milligrams (mg) once a day for the first 3 days. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day.
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Is bupropion good for anxiety?

Also known as bupropion, Wellbutrin has been established as an effective antidepressant demonstrating an impressive ability to reduce anxiety levels. There are many benefits to Wellbutrin as an anxiety treatment, including its lack of common mood medication symptoms, like weight gain and sexual side effects.
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What are the benefits of bupropion?

Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.
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Why do people gain weight on antidepressants?

Antidepressants interfere with serotonin, the neurotransmitter that regulates anxiety and mood while also controlling appetite. In particular, these changes may increase cravings for carbohydrate-rich foods, such as bread, pasta, and desserts. When people are depressed, their appetites are affected.
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How can I lose weight after antidepressants?

How to lose weight after antidepressants
  1. Change medication. Some antidepressants aren't linked to weight gain. ...
  2. Look at your lifestyle. One study on SSRI use and weight gain found that weight gain was more likely in people who also had a Western diet, were sedentary, and smoked⁸. ...
  3. Get active. ...
  4. Get a good night's sleep.
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How can I lose weight while on antidepressants?

Increasing both aerobic exercise and strength training, ideally four times a week for a minimum of 30 to 45 minutes, can increase muscle tone and metabolism and reduce fat stores. Regular exercise has also been shown to reduce risk for depression relapse when combined with a stable medication regimen.
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Does bupropion XL make you lose weight?

Another study in 2016 also found compelling evidence that bupropion promotes weight loss, and a study in 2019 showed bupropion patients simply had no weight change compared to patients on other antidepressants.
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How long can you take Wellbutrin?

Overview of Wellbutrin Withdrawal

Some people take them for a few weeks or months, whereas others take them for years. About one in four people on antidepressants have been taking them for 10 or more years. 1 Once they find an antidepressant that works for them, many people continue taking it indefinitely.
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Can bupropion cause anger?

Bupropion may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed.
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Does Wellbutrin affect exercise?

Bupropion has a marked central noradrenergic effect on the hormonal response to exercise, but no effect on the outcome of performance.
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