How common is Cushings in horses?

Equine Cushing's disease, also known as PPID

PPID

Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, and is classically associated with the formation of a long, wavy coat (hirsutism) and chronic laminitis.

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Pituitary pars intermedia dysfunction - Wikipedia

, is thought to affect 20% of horses over the age of 15, and is the 5th most common disease syndrome recognised in horses and ponies in the UK*.

What percentage of horses get Cushings?

Equine Cushing's is one of the most commonly diagnosed equine endocrine (hormonal) disorders. It is estimated to affect approximately 0.1% to 0.5% of all horses. Cushing's is usually diagnosed in older horses (the average age of affected horses is 19 years), but it also can occur in young horses.

What triggers Cushings in horses?

Causes. The underlying cause of PPID is loss of inhibition of the pars intermedia region of the pituitary gland. As a result, the gland becomes enlarged and there is a marked increase in the production of certain hormones.

How many horses have Cushing's?

All horses are at risk for PPID. Current estimates suggest that between 20 and 33% of all horses develop PPID by the age of 20. This makes PPID the most common endocrine condition of horses. In days gone by, veterinarians and owners relied heavily on the classic signs of PPID to make a diagnosis.

What age do horses get Cushing's?

Equine Cushing's Disease is a condition of older horses and typically develops in horses over 15 years of age, although it can develop in younger animals.

Ask the Vet - What is Cushing's Disease in horses?

How do you prevent Cushings in horses?

Although Cushing's disease cannot always be prevented, there are precautions you can take to lower the risk. “The most important thing is to keep your horse's weight down, providing proper nutrition, which means to feed him only what he really needs,” Langer says. Sugar intake should be minimized.

How can you tell if a horse has Cushings?

Do all horses get Cushings?

All breeds of horses can be diagnosed with Cushing's disease, but ponies and Morgan breeds may be predisposed.

Can you reverse Cushings in horses?

The Right Medicine PPID cannot be cured, but its effects can be controlled with medication and management. The drug most commonly used to treat horses with PPID is pergolide mesylate, a dopamine agonist that helps to regulate the pituitary gland.

Can you still ride a horse with Cushings?

What should be the cut-off sign not to ride him? You should first consult with your veterinarian before beginning an exercise or riding program. However, generally speaking, horses with Cushing's can be ridden like any other horse, particularly if the Cushing's syndrome is well controlled with medication.

Do all Cushings horses get laminitis?

Equine Cushing's cases always develop laminitis if they live long enough. They may become immunosuppressed and subject to a variety of parasitic or infectious agents such as helminthiasis or pneumonia. Many cases show muscle loss and become polydipsic and polyphagic; they may be diabetic.

How much does it cost to treat Cushings in horses?

Pergolide and cyproheptadine are the most commonly used medications. Pergolide is typically most effective. Treatment for a full-sized horse usually costs between $80-$100 per month. Cyproheptadine is less effective, but is also less expensive, at about $35 per month.

What is the best hay to feed a horse with Cushing's?

Alfalfa averages 10-15% NSC, and oat hay is very high, averaging 22%. Alfalfa can be a good option for a horse with Cushings if they are a hard time holding their weight because it is more calorie-dense than grass hay.

When is the best time of year to test a horse for Cushing's?

If a horse is showing symptoms of Cushing's Disease and has a normal ACTH level, then we recommend either re-testing ACTH levels during Mid-August to Mid-February, or a TRH stimulation test.

Does a horse with Cushings need medication?

How do you treat Equine Cushing's disease? Treatment is fairly simple. It consists of an oral medication (Pergolide) in the form of a tablet given once daily. PRASCEND is a FDA-approved formulation of pergolide.

Can Cushings in horses be treated naturally?

Good hoof-care combined with nutritional management and the application of other modalities, including acupuncture and Chinese and Western herbs, can complete the healing process. The successful treatment of equine Cushing's syndrome is one of the best examples of treating a disease using the holistic approach.

Can horses with Cushings eat grass?

Pasture grasses can have a high NSC content, especially during the spring and fall seasons, and the risk of colic and laminitis is greater when horses are on pasture. Since laminitis and founder are more common in horses with Cushing's disease, pasture grazing should be severely limited or totally avoided.

What happens if you don't treat Cushings in horses?

If a horse has untreated Cushing's Disease, it is more likely to develop laminitis and the laminitis will be more difficult to control. If an equine has any of the clinical signs suggestive of Cushing's, a blood sample can be taken to check ACTH levels in the blood.

What should I feed my senior horse with Cushings?

Increased energy requirements can be met by feeding alfalfa (lucerne) hay or chaff, super-fibers such as beet pulp and soy hulls, or a low- to moderate-NSC feed. Feeds that are higher in fat (greater than 6%) are preferred as they are less reliant on carbohydrates for energy.

Can you feed oats to horses with Cushings?

Even though oats are the grain lowest in sugar and starch, at around 45 to 50% starch they are still far too high in starch for horses on a low sugar and starch diet, eg insulin resistant horses, horses prone to laminitis, those with disorders like Cushings or PSSM etc, as well as many horses who are prone to ulcers, ...

How quickly does Prascend work?

Clinical improvement is usually expected within 6-12 weeks of starting Prascend treatment, however the length of time between initiation of treatment to being able to see a response can vary from one horse or pony to another.

Does Cushing's shorten a horse's life?

Cushing's disease is not a death sentence. Despite the fact that there is no cure, there are several management practices that can keep an affected horse in use and in good health for many years following diagnosis.

Does Cushing's cause laminitis?

Recurrent and often unexplained bouts of laminitis along with an abnormal hair coat are two of the most common clinical signs of a horse with Cushing's.

How long can horses be on PRASCEND?

24-month stability at labeled storage conditions which allows for consistent, reliable dosing. PRASCEND is for use in horses only.

Can you PRASCEND every other day?

Giving 0.5 mg every other day - the datasheet states that Prascend should be given once daily. As the average half life of pergolide has been found to be around 6 hours in horses (Abra Wright Pharmacokinetics of pergolide in normal mares, MSc thesis 2009), extending the time between doses seems counter-intuitive.