Does Zoloft or Lexapro cause more weight gain?

While head-to-head comparisons for Zoloft vs Lexapro are not available, studies suggest that both can cause weight gain when taken long-term. A study published in the Journal of Clinical Medicine in 2016, for example, found that people taking Zoloft over a two-year period gained an average of 10.5 pounds.
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Which antidepressants cause the most weight gain?

Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.
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Does Zoloft cause you to gain weight?

Experts say that for up to 25% of people, most antidepressant medications -- including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft -- can cause a weight gain of 10 pounds or more.
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Which antidepressant causes least weight gain?

Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline.
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Will Lexapro make me fat?

Weight gain while taking Lexapro (escitalopram) is not uncommon. The medication, often prescribed to treat depression or anxiety disorders, belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). These medications all list weight gain as a possible side effect.
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Does Zoloft cause weight gain? | FNP Explains | Chat and Chill



Can you lose weight on Zoloft?

Weight gain is a common complaint of patients receiving antidepressant drug treatment. The antidepressant sertraline, a selective serotonin uptake inhibitor, has been reported to promote weight loss.
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How do I keep from gaining weight on Zoloft?

How to Avoid Sertraline Weight Gain
  1. Weigh yourself before you start. ...
  2. Maintain your normal eating habits. ...
  3. Stay active. ...
  4. Weigh yourself weekly, not daily. ...
  5. If you gain weight, tell your healthcare provider. ...
  6. If you lose weight, tell your healthcare provider.
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How do I not gain weight on Lexapro?

If you gain weight when taking Lexapro, you may be able to lose weight with regular exercise and healthy eating. Talk to your doctor or a registered dietitian for support and individual guidance.
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What is the difference between Zoloft and Lexapro?

The only difference between them and their brand-name counterparts is that they tend to cost significantly less. A generic version of Lexapro is available, which is called escitalopram. The generic version of Zoloft is called sertraline, and it is available in tablet and liquid forms.
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Does Zoloft increase appetite?

SSRIs can increase appetite. You may feel strong cravings for foods rich in carbohydrates. Be mindful of what you are eating when on Zoloft. Simply paying attention to what you're eating—on purpose, and without judging yourself—can often lead people to maintain a healthy weight.
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What is the best antidepressant that doesn't cause weight gain?

Antidepressants that do not cause weight gain

According to current scientific research, antidepressants that are least likely to cause weight gain are: Effexor (venlafaxine) Wellbutrin (bupropion) Nefazodone (however, this is rarely used because it can cause severe liver problems)
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How can I avoid gaining weight on antidepressants?

As simple as it may sound, the best chance of avoiding, or lessening further, undesirable weight gain when taking a prescribed antidepressant or antipsychotic medication, is to simultaneously participate in a formal weight management program.
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Which causes more weight gain Prozac or Zoloft?

That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.
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Which anti anxiety medication causes weight loss?

Bupropion is an antidepressant that may lead to weight loss in some people. Antidepressants are a common form of treatment for depression.
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Is it OK to switch from Zoloft to Lexapro?

Can you take Lexapro and Zoloft together? Lexapro and Zoloft should not be taken together. Because both medications are SSRIs, taking them together can lead to dangerously high levels of serotonin collecting in your body. This is called serotonin syndrome, and it can be fatal.
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What antidepressant is better than Lexapro?

Zoloft is approved by the U.S. Food and Drug Administration (FDA) to treat more conditions than Lexapro, but both may be prescribed for off-label uses.
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What is the best alternative to Lexapro?

Selective serotonin reuptake inhibitors (SSRIs).

SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro).
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Will I lose weight if I stop Lexapro?

If you decrease your daily calorie intake as a result, you could potentially lose weight by stopping your antidepressants. On the other hand, if you experience loss of appetite with depression, and your depression comes back after stopping antidepressants, you may also lose weight.
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Does Lexapro cause weight gain than Prozac?

While few head-to-head comparisons of Prozac vs Lexapro weight gain are available, studies indicate that both medications can cause weight gain. According to a 2011 study in the Journal of Obesity, people who took Lexapro over an 8-month (i.e. short-term) period gained around 4 pounds, on average.
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Does 50mg Zoloft cause weight gain?

Like any medication, antidepressants in the class of selective serotonin reuptake inhibitors (SSRIs) have potential side effects. For some people who take an SSRI such as Prozac (fluoxetine) or Zoloft (sertraline), one of these possible side effects is weight gain.
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Is 50mg of Zoloft a lot?

Most studies suggest that the most effective dose of Zoloft is 50 mg per day. This dose is proven to be the most effective and tolerable dose for most patients.
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How can I lose weight after antidepressants?

How to lose weight after antidepressants
  1. Change medication. Some antidepressants aren't linked to weight gain. ...
  2. Look at your lifestyle. One study on SSRI use and weight gain found that weight gain was more likely in people who also had a Western diet, were sedentary, and smoked⁸. ...
  3. Get active. ...
  4. Get a good night's sleep.
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Which SSRI is best for weight loss?

Most antidepressant medications are more commonly associated with weight gain, but there are three that have been connected to weight loss:
  • Bupropion (Wellbutrin)
  • Fluoxetine (Prozac)
  • Duloxetine (Cymbalta)
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Does serotonin cause weight gain?

According to the study published in Natural Medicine, there are 2 types of serotonin. The type that is known for its effects on mood and appetite only accounts for 5% of serotonin in the body, while the other 95%, called peripheral serotonin, plays a role in obesity.
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Why have I been gaining weight so fast?

Poor sleep, sedentary activities, and eating too many processed or sugary foods are just some of the habits that may increase your risk of weight gain. Yet, a few simple steps — such as mindful eating, exercise, and focusing on whole foods — can help you reach your weight loss goals and improve your overall health.
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